Protein kinase C activation is required for the lead-induced inhibition of proliferation and differentiation of cultured oligodendroglial progenitor cells

Brain Research

Volumn 929, Issue 1, 2002, Pages 87-95

  Deng, Wenbin ^a   Poretz, Ronald D ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Differentiation; Lead toxicity; Oligodendrocyte; PKC; Proliferation; Survival

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BISINDOLYLMALEIMIDE; BISINDOLYLMALEIMIDE I; BISINDOLYLMALEIMIDE V; LEAD; PHORBOL DIDECANOATE; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DEVELOPMENTAL STAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; CARCINOGENS; CASPASE 3; CASPASES; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; LEAD; LEAD POISONING, NERVOUS SYSTEM; OLIGODENDROGLIA; PHORBOL ESTERS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS;

EID: 0036498264     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03385-6     Document Type: Article

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