Effect of Intermittent and Continuous Exposure to Electromagnetic Fields on Cultured Hippocampal Cells

Bioelectromagnetics

Volumn 23, Issue 2, 2002, Pages 97-105

  Boland, A ^a   Delapierre, D ^a   Mossay, D ^a   Dresse, A ^a   Seutin, V ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

50 Hz; Cell death; Cultured nerve cells; ELF; Iron; Nitric oxide; Oxidative stress

Indexed keywords

CELL CULTURE; CELL DEATH; ELECTROMAGNETIC FIELDS; IRON OXIDES; NEURONS; NITRIC OXIDE;

50 HZ; CELL MORTALITY; CELL-BE; CELL/B.E; CELL/BE; CULTURED NERVE CELLS; ELF; EXPOSED TO; HIPPOCAMPAL CELLS; INTERMITTENT EXPOSURES;

OXIDATIVE STRESS;

FERROUS ION; LACTATE DEHYDROGENASE; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; FERROUS SULFATE;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ELECTROMAGNETIC FIELD; ENZYME ANALYSIS; HIPPOCAMPUS; MORTALITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIATION EXPOSURE; RAT; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; HUMAN; PHYSIOLOGY;

CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; ELECTROMAGNETIC FIELDS; FERROUS COMPOUNDS; HIPPOCAMPUS; HUMANS; NITRIC OXIDE DONORS; NITROPRUSSIDE; OXIDATIVE STRESS;

EID: 0036483863     PISSN: 01978462     EISSN: None     Source Type: Journal    
DOI: 10.1002/bem.102     Document Type: Article

References (65)

1. Ahlbom A, Day N, Feychting M, Roman E, Skinner J, Dockerty J, Linet M, Mc Bride M, Michaelis J, Olsen JH, Tynes T, Verkasalo PK. 2000. A pooled analysis of magnetic fields and childhood leukaemia. Br J Cancer 83:692-698.
2. Bianchi N, Crosignani P, Rovelli A, Tittarelli A, Camelli CA, Rossitto F, Vanelli U, Porro E, Berrino F. 2000. Overhead electricity power lines and childhood leukemia: a registry-based, case-control study. Tumori 86:195-198.
3. Blanc EM, Kelly JF, Mark RJ, Waeg G, Mattson MP. 1997a. 4-Hydroxynonenal, an aldehydic product of lipid peroxidation; impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on Gαq/11. J Neurochem 69:570-580.
4. Blanc EM, Toborek M, Mark RJ, Hennig B, Mattson MP. 1997b. Amyloid B-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells. J Neurochem 68:1870-1881.
5. Boland A, Delapierre D, Mossay D, Hans P, Dresse A. 2000. Propofol protects cultured brain cells from iron-induced death: comparison with trolox. Eur J Pharmacol 404: 21-27.
6. Cain CD, Thomas DL, Adey WR. 1993. 60 Hz magnetic field acts as co-promoter in focus formation of C3H/10T1/2 cells. Carcinogenesis 14:955-960.
7. Campbell-Beachler M, Ishida-Jones T, Haggren W, Phillips JL. 1998. Effect of 60 Hz magnetic field exposure on c-fos expression in stimulated PC12 cells. Mol Cell Biochem 189:107-111.
8. Chiang H. 1993. VDT pulse magnetic field enhances teratogenic effect of ara-c in mice. Chung. Hua. Yu. Fang. I. Hsueh. Tsa Chih. 27:215-217.
9. Dahiyat M, Cumming A, Harrington C, Wischik C, Xuereb J, Corringan F, Breen G, Shaw D, St Clair D. 1999. Association between Alzheimer's disease and NOS3 gene. Ann Neurol 46:664-667.
10. Dawson TM, Dawson VL, Snyder SH. 1994. Molecular mechanism of nitric oxide actions in the brain. Ann NY Acad Sci 738:76-85.
11. Feychting M, Pedersen NL, Svedberg P, Floderus B, Gatz M. 1998. Dementia and occupational exposure to magnetic fields. Scand J Work Environ Health 24:46-53.
12. Fiorani M, Biagiarelli B, Vetrano F, Guidi G, Dacha M, Stocchi V. 1997. In vitro effects of 50 Hz magnetic fields on oxidatively damaged rabbit red blood cells. Bioelectromagnetics 18:125-131.
13. 2+]i. Exp Neurol 133:153-163.
14. 2+ oscillations in human leukemia T-cells are reduced by 50 Hz magnetic fields. Bioelectromagnetics 20:269-276.
15. Garthwaite J. 1991. Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci 14:60-67.
16. Halliwell B, Gutteridge JMC. 1992. Biologically relevant metal ion-dependent hydroxyl radical generation an update. FEBS Lett 307:108-112.
17. Hémar A, Olivo JC, Williamson E, Saffrich R, Dotti CG. 1997. Dendroaxonal transcytosis of transferrin in cultured hippocampal and sympathetic neurons. J Neurosci 17:9026-9034.
18. Hensley K, Maidt ML, Hong Sang Y, Markesbery WR, Floyd RA. 1998. Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. J Neurosci 18:8126-8132.
19. Hintenlang DE. 1993. Synergistic effect of ionizing radiation and 60 Hz magnetic fields. Bioelectromagnetics 14:545-551.
20. Hurych J, Mirejovska E, Holusa R, Bubenikova D. 1996. Effects of magnetic field exposure on the development of lung fibrosis elicited by industrial pollutants. Toxicol Lett 88:305-311.
21. Johansen C, Olsen JH. 1998. Mortality from amyotrophic lateral sclerosis, other chronic disorders, and electric shocks among utility workers. Am J Epidemiol 148:362-368.
22. Katsir G, Parola AH. 1998. Enhanced proliferation caused by a low frequency weak magnetic field in chick embryo fibroblasts is suppressed by radical scavengers. Biochem Biophys Res Commun 252:753-756.
23. Koana T, Okada MO, Ikehata M, Nakagawa M. 1997. Increase in the mitotic recombination frequency in Drosophila melanogaster by magnetic field exposure and its suppression by vitamin E supplement. Mutat Res 373:55-60.
24. Koh JY, Choi D. 1987. Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J Neurosci Methods 20:83-90.
25. Lai H, 1996. Spatial learning deficit in the rat after exposure to a 60 Hz magnetic field. Bioelectromagnetics 17:494-496.
26. Lai H, Carino M. 1999. 60 Hz magnetic fields and central cholinergic activity: effects of exposure intensity and duration. Bioelectromagnetics 20:284-289.
27. Lindström E, Lindström P, Berglund A, Hansson MK, Lundgren E. 1993. Intracellular calcium oscillations induced in a T-cell line by a weak 50 Hz magnetic field. J Cell Physiol 156:395-398.
28. Linet MS, Hatch E, Kleinerman RA, Robinson RA, Kaune WT, Freidman DR, Severson RK, Haines CM, Hartsock CT, Niwa S, Wacholder S, Tarone RE. 1997. Residential exposure to magnetic fields and acute lymphoblastic leukemia in children. N Engl J. Med 337:1-7.
29. Litovitz TA, Penafiel M, Krause D, Zhang D, Mullins JM. 1997. The role of temporal sensing in bioelectromagnetic effects. Bioelectromagnetics 18:388-395.
30. Loomis A, Kromhout H, Kleckner RC, Savitz DA. 1998. Effects of the analytical treatment of exposure data on associations of cancer and occupational magnetic field exposure. Am J Ind Med 34:49-56.
31. Mailhes JB, Young D, Marino AA, London SN. 1997. Electromagnetic fields enhance chemically-induced hyperploidy in mammalian oocytes. Mutagenesis 12:347-351.
32. Mattson MP. 1998. Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity. Trends Neurosci 21:53-57.
33. Mattson MP, Barger SW, Begley JG, Mark RJ. 1995. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol 46:187-216.
34. Mattson MP, Cheng B, Culwell AR, Esch FS, Lieberburg I, Rydel RE. 1993a. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the B-amyloid precursor protein. Neuron 10:243-254.
35. Mattson MP, Lovell MA, Ehmann WD, Markesbery WR. 1993b. Comparison of the effects of elevated intracellular aluminium and calcium levels on neuronal survival and tau immunoreactivity. Brain Res 602:21-31.
36. Nordenson I, Hansson MK, Andersson G, Sandström M. 1994. Chromosomal aberration in human amniotic cells after intermittent exposure to fifty hertz magnetic fields. Bioelectromagnetics 15:293-301.
37. Olanow CW. 1993. A radical hypothesis for neurodegeneration. Trends Neurosci 16:439-444.
38. Oshiro S, Nozawa K, Cai Y, Hori M, Kitajima S. 1998. Characterization of a transferrin-independent iron uptake system in rat primary cultured cortical cells. J Med Dent Sci 45:171-176.
39. Phillips JL, Haggren W, Thomas WJ, Ishida-Jones T, Ross AW. 1992. Magnetic field-induced changes in specific gene transcription. Biochim Biophys Acta 1132:140-144.
40. Pieper AA, Verma A, Zhang J, Snyder SH. 1999. Poly (ADP-ribose) polymerase, nitric oxide and cell death. Trends Pharmacol Sci 20:171-181.
41. Rao S, Henderson AS. 1996. Regulation of c-fos is affected by electromagnetic fields. J Cell Biochem 63:358-365.
42. Richardson JS. 1993. Free radicals in the genesis of Alzheimer's disease. Ann NY Acad Sci 695:73-76.
43. Roy S, Noda Y, Eckert V, Traber MG, Mori A, Liburdy R, Packer L. 1995. The phorbol 12-myristate 13-acetate (PMA)-induced oxidative burst in rat peritoneal neutrophils is increased by a 0.1 mT (60 Hz) magnetic field. FEBS Lett 376:164-166.
44. Savitz DA, Checkoway H, Loomis DP. 1998a. Magnetic field exposure and neurodegenerative disease mortality among electric utility workers. Epidemiology 9:398-404.
45. Savitz DA, Loomis AP, Tse CK. 1998b. Electrical occupations and neurodegenerative disease: analysis of US mortality data. Arch Environ Health 53:71-74.
46. Scaiano JC, Cozens FL, McLean J. 1994a. Model for the rationalization of magnetic field effects in vivo. Application of the radical - pair mechanism to biological systems. Photochem Photobiol 59:585-589.
47. Scaiano JC, Cozens FL, Mohtat N. 1995. Influence of combined AC-DC magnetic fields on free radicals in organized and biological systems. Development of a model and application of the radical pair mechanism to radicals in micelles. Photochem Photobiol 62:818-829.
48. Scaiano JC, Mothat N, Cozens FL, McLean J, Thansandote A. 1994b. Application of the radical pair mechanism to free radicals in organized systems: can the effects of 60 Hz be predicted from studies under static fields? Bioelectromagnetics 15:549-554.
49. Schulte PA, Burnett CA. 1997. EMFs and Alzheimer's disease. Neurology 49:312.
50. Schulte PA, Burnett CA, Boeniger MF, Johnson J. 1996. Neurodegenerative diseases: occupational occurence and potential risk factors, 1982 through 1991. Am J Public Health 86:1281-1288.
51. Selmaoui B, Touitou Y. 1995. Sinusoidal 50-Hz magnetic field depress rat pineal NAT activity and serum melatonin: role of duration and intensity of exposure. Life Sci 57:1351-1358.
52. Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G. 1997. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci 17:2653-2657.
53. Smith MA, Sayre LM, Monnier VM, Perry G. 1995. Radical AGEing in Alzheimer's disease. Trends Neurosci. 18:172-176.
54. Sobel E, Davanipour Z, Sulkava R, Erkinjuntti T, Wikstrom J, Henderson VW, Buckwalter G, Bowman JD, Lee PJ. 1995. Occupations with exposure to electromagnetic fields: a possible risk factor for Alzheimer's disease. Am J Epidemiol 142:515-524.
55. Sobel E, Dunn M, Davanipour Z, Qian Z, Chui HC. 1996. Elevated risk of Alzheimer's disease among workers with likely electromagnetic field exposure. Neurology 47:1477-1481.
56. Stamler JS, Singel DJ, Locaslzo J. 1992. Biochemistry of nitric oxide and its redox-activated forms. Science 258:1898-1902.
57. Szabo C, Dawson VL. 1998. Role of poly(ADP-ribose) synthetase in inflammation and ischemia-reperfusion. Trends Pharmacol Sci 19:287-298.
58. Torreilles F, Salman-Tabcheh S, Guérin M-C, Toreilles J. 1999. Neurodegenerative disorders: the role of peroxynitrite. Brain Res Rev 30:153-163.
59. Tynes T, Andersen A, Langmark F. 1992. Incidence of cancer in Norwegian workers potentially exposed to electromagnetic fields. Am J Epidemiol 136:81-88.
60. VanDyke K. 1997. The possible role of peroxynitrite in Alzheimer's disease: a simple hypothesis that could be tested more thoroughly. Med Hypotheses 48:375-380.
61. Villeneuve PJ, Agnew DA, Miller AB, Corey PN. 2000a. Non-Hodgkin's lymphoma among electric utility workers in Ontario: the evaluation of alternate indices of exposure to 60 Hz electric and magnetic fields. Occup Environ Med 57:249-257.
62. Villeneuve PJ, Agnew DA, Miller AB, Corey PN, Purdham JT. 2000b. Leukemia in electric utility workers: the evaluation of alternative indices of exposure to 60 Hz electric magnetic fields. Am J Ind Med 37:607-617.
63. Wieraszko A. 2000. Dantrolene modulates the influence of steady magnetic fields on hippocampal evoked potential in vitro. Bioelectromagnetics 21:175-182.
64. Williams LR. 1995. Oxidative stress, age-related neurodegeneration, and the potential for neurotrophic treatment. Cerebr Brain Metab Rev 7:55-73.
65. Yost MG, Liburdy RP. 1992. Time-varying and static magnetic fields act in combination to alter calcium signal transduction in the lymphocyte. FEBS Lett 296:117-122.