Leukemia in electric utility workers: The evaluation of alternative indices of exposure to 60 Hz electric and magnetic fields

American Journal of Industrial Medicine

Volumn 37, Issue 6, 2000, Pages 607-617

  Villeneuve, Paul J ^a,b   Agnew, David A ^a,c   Miller, Anthony B ^a   Corey, Paul N ^a   Purdham, James T ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c ONTARIO POWER GENERATION   (Canada)

Author keywords

Cancer promoter; Electric fields; Exposure assessment; Leukemia; Magnetic fields

Indexed keywords

ARTICLE; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; ELECTRIC FIELD; HUMAN; LEUKEMIA; MAGNETIC FIELD; MALE; OCCUPATIONAL EXPOSURE; RISK ASSESSMENT;

ADULT; CASE-CONTROL STUDIES; ELECTROMAGNETIC FIELDS; FEMALE; HUMANS; LEUKEMIA; MALE; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; ONTARIO; RISK ASSESSMENT;

EID: 0034012350     PISSN: 02713586     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0274(200006)37:6<607::AID-AJIM5>3.0.CO;2-L     Document Type: Article

References (36)

1. Armstrong BG, Deadman JE, Thériault G. 1990. Comparison of indices of ambient exposure to 60-Hertz electric and magnetic fields. Bioelectromagnetics 11:337-347.
2. Baum A, Mevissen M, Kamino K, Mohr U, Loscher W. 1995. A histopathological study on alterations in DMBA-induced mammary carcinogenesis in rats with 50 Hz, 100 mT magnetic field exposures. Carcinogenesis 16:119-125.
3. Beniashvili DS, Bilanishvili VG, Menabde MZ. 1991. Low-frequency electromagnetic radiation enhances the induction of rat mammary tumors by nitrosomethyl urea. Cancer Lett 61:75-79.
4. Blask DE. 1990. The emerging role of the pineal gland and melatonin in oncogenesis. In: Wilson B, Stevens R, Anderson L, editors. Extremely low frequency fields: the question of cancer. Richland Wash: Battelle Press.
5. Byus CV, Pieper SA, Adey WR. 1987. The effects of low-energy 60-Hz environmental electromagnetic fields upon the growth-related enzyme ornithine decarboxylase. Carcinogenesis 8:1385-1389.
6. Coleman M, Bell J, Skeet R. 1983. Leukaemia incidence in electrical workers [letter]. Lancet 1:982-983.
7. Cridland NA. 1997. Effects of power frequency EMF exposures at the cellular level. Radiation Protection Dosimetry 72:279-290.
8. Deadman JE, Camus M, Armstrong BG, Heroux P, Cyr D, Plante M, Theriault G. 1988. Occupational and residential 60-Hz electromagnetic fields and high-frequency electric transients: exposure assessment using a new dosimeter. Am Ind Hyg Assoc J 49:409-419.
9. Dees C, Garrett S, Henley D, Travis C. 1996. Effects of 60-Hz fields, estradiol and xenoestrogens on human breast cancer cells. Radiat Res 146:444-452.
10. Feychting M, Forssen U, Floderus B. 1997. Occupational and residential magnetic field exposure and leukemia and central nervous system tumors. Epidemiology 8:384-389.
11. Floderus B, Persson T, Stenlund C, Wennberg A, Öst A, Knave B. 1993. Occupational exposure to electromagnetic fields in relation to leukemia and brain tumors: a case control study in Sweden. Cancer Causes Control 4:465-476.
12. Guénel P, Nicolau J, Imbernon E, Chevalier A, Goldberg M. 1996. Exposure to 50-Hz electric field and incidence of leukemia, brain tumors and other cancers among French electric utility workers. Am J Epidemiol 144:1107-1021.
13. Hardell L, Holmberg B, Malker H, Paulsson LE. 1995. Exposure to extremely low frequency electromagnetic fields - an evaluation of epidemiological and experimental findings. Eur J Cancer Prev 4 (Suppl. 1):3-107.
14. Héroux P. 1991. A dosimeter for assessment of exposures to ELF fields. Bioelectromagnetics 12:241-257.
15. Kheifets LI, London SJ, Peters JM. 1997. Leukemia risk and occupational electric field exposure in Los Angeles County, California. Am J Epidemiol 146:87-90.
16. Lacy-Hulbert A, Wilkins RC, Hesketh TR, Metcalfe JC. 1995. No effect of 60 Hz electromagnetic fields on MYC or beta-actin expression in human leukemic cells. Radiat Res 144:9-17.
17. London SJ, Bowman JD, Sobel E, Thomas DC, Garabrant DH, Pearce N, Bernstein L, Peters JM. 1994. Exposure to magnetic fields among electrical workers in relation to leukemia risk in Los Angeles County. Am J Ind Med 26:47-60.
18. Loscher W, Wahnschaffe U, Mevissen M, Lerchl A, Stamm A. 1994. Effects of weak alternating magnetic fields on nocturnal melatonin production and mammary carcinogenesis in rats. Oncology 51: 288-295.
19. Mantanoski GM, Elliott EA, Breyesse PN, Lynberg MC. 1993. Leukemia in telephone linemen. Am J Epidemiol 137:609-619.
20. McLean JR, Thansandote A, Lecuyer D, Goddard M. 1997. The effect of 60-Hz magnetic fields on co-promotion of chemically induced skin tumors on SENCAR mice: a discussion of three studies. Environ Health Perspect 105:94-96.
21. McDowall ME. 1983. Leukaemia mortality in electrical workers in England and Wales [letter]. Lancet 1:246.
22. Mevissen M, Stamm A, Buntenkotter S, Zwingelberg R, Wahnschaffe U, Loscher W. 1993. Effects of magnetic fields on mammary tumor development induced by 7,12-dimethylbenz(a)anthracene in rats. Bioelectromagnetics 14:131-143.
23. Mevissen M, Lerchl A, Szamel M, Loscher W. 1996. Exposure of DMBA-treated female rats in a 50-Hz, 50 microTesla magnetic field: effects of mammary tumor growth, melatonin levels and T-lymphocyte activation. Carcinogenesis 17:903-910.
24. Milham S, Hatfield JB, Tell R. 1999. Magnetic fields from steel belted radial tires: implications for epidemiologic studies. Bioelectromagnetics 20:440-445.
25. Milham S. 1982. Mortality from leukemia in workers exposed to electrical and magnetic fields [letter]. N Engl J Med 307:249.
26. Miller AB, To T, Agnew DA, Wall C, Green LM. 1996a. Leukemia following occupational exposure to 60-Hz electric and magnetic fields among Ontario electric utility workers. Am JEpidemiol 144:150-160.
27. Miller AB, To T, Wall C. 1996b.Technical report on the epidemiological study on the long-term effects of exposure to 60 Hertz electric and magnetic fields: Ontario Hydro sectorial analysis. Department of Preventive Medicine and Biostatistics, University of Toronto.
28. Rannug A, Holmberg B, Ekström T, Mild KH, Gimenez-Conti I, Slaga TJ. 1994. Intermittent 50 Hz magnetic field and skin tumor promotion in SENCAR mice. Carcinogenesis 1994;15:153-157.
29. Sahl JD, Kelsh MA, Greenland S. 1993. Cohort and nested case-control studies of haematopoetic cancers and brain cancer among electric utility workers. Epidemiology 1993;4:104-114.
30. Sahl JD, Kelsh MA, Smith RW, Aseltine DA. 1994. Exposure to 60 Hz magnetic fields in the electric utility work environment. Bioelectromagnetics 15:21-32.
31. Savitz DA, Ohya T, Loomis DP, Senior RS, Bracken TD, Howard R. 1994. Correlations among indices of electric and magnetic field exposure in electric utility workers. Bioelectromagnetics 15: 193-204.
32. Selvin S. 1996. Statistical analysis of epidemiologic data. 2nd ed.. New York: Oxford University Press, p 260-263.
33. Tenforde TS, Kaune WT. 1987. Interaction of extremely low frequency electric and magnetic fields with humans. Health Phys 53: 585-606.
34. Thériault G, Goldberg M, Miller AB, Armstrong B, Guenel P, Deadman J, Imbernon E, To T, Chevalier A, Cyr D, Wall C. 1994. Cancer risks associated with occupational exposure to magnetic fields among electric utility workers in Ontario and Quebec, Canada and France: 1970-1989. Am J Epidemiol 139:550-572.
35. Villeneuve PJ, Agnew DA, Corey PN, Miller AB. 1998. Alternate indices of electric and magnetic field exposures among Ontario electrical utility workers. Bioelectromagnetics 19:140-151.
36. Wright WE, Peters JM, Mack TM. 1982. Leukaemia in workers exposed to electrical and magnetic fields [letter]. Lancet 2; 1160-1161.