The dynamin A ring complex: Molecular organization and nucleotide-dependent conformational changes

EMBO Journal

Volumn 21, Issue 3, 2002, Pages 240-250

  Klockow, Boris ^a   Tichelaar, Willem ^a   Madden, Dean R ^a,b   Niemann, Hartmut H ^a   Akiba, Toshihiko ^c   Hirose, Keiko ^d   Manstein, Dietmar J ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c NATL INST FOR ADV INTERDISC RES   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Conformational changes; Protease inhibitor; Protein assembly; Ring complex

Indexed keywords

DYNAMIN; DYNAMIN A; GUANOSINE TRIPHOSPHATASE; NUCLEOTIDE; PROTEINASE INHIBITOR; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CHEMICAL MODIFICATION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DICTYOSTELIUM DISCOIDEUM; HUMAN; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DOMAIN; SPECIES DIFFERENCE; STRUCTURE ANALYSIS;

ANIMALS; DICTYOSTELIUM; DIMERIZATION; DYNAMINS; GTP PHOSPHOHYDROLASES; HUMANS; PROTEIN CONFORMATION; PROTOZOAN PROTEINS;

ANIMALIA; DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; PROTOZOA;

EID: 0036469355     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.3.240     Document Type: Article

References (50)

1. Correlation between self-association modes and GTPase activation of dynamin
2. Dynamin is membrane-active: Lipid insertion is induced by phosphoinositides and phosphatidic acid
3. Dynamin assembles into spirals under physiological salt conditions upon the addition of GDP and T-phosphate analogues
4. The portal protein of bacteriophage SPP1: A DNA pump with 13-fold symmetry
5. The role of dynamin and its binding partners in coated pit invagination and scission
6. Dynamin spirals
7. Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding
8. Increased GTP-binding to dynamin II does not stimulate receptor-mediated endocytosis
9. Amino acid repeat patterns in protein sequences: Their diversity and structural-functional implications
10. Arabidopsis dynamin-like 2 that binds specifically to phosphatidylinositol 4-phosphate assembles into a high-molecular weight complex in vivo and in vitro
11. The tobacco mosaic virus particle: Structure and assembly
12. ts1 J
13. Dynamin: Possible mechanism of "Pinchase" action
14. Fission of biological membranes: Interplay between dynamin and lipids
15. GTPase activity of dynamin and resulting conformation change are essential for endocytosis
16. The dynamin family of mechanoenzymes: Pinching in new places
17. Interferon-induced Mx proteins form oligomers and contain a putative leucine zipper
18. Domain structure and intramolecular regulation of dynamin GTPase
19. Structure of mouse Mx1 protein. Molecular assembly and GTP-dependent conformational change
20. Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms
21. Multiple distinct coiled-coils are involved in dynamin self-assembly
22. Cytosolic ATPases, p97 and NSF, are sufficient to mediate rapid membrane fusion
23. Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins
24. Structure of Lambricus terrestris hemoglobin at 30 Å resolution determined using angular reconstitution
25. Dynamin and its partners: A progress report
26. Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid
27. Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel
28. Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis
29. Dynamin: GTP controls the formation of constricted coated pits, the rate limiting step in clathrin-mediated endocytosis
30. Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein
31. Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules
32. A model for dynamin self-assembly based on binding between three different protein domains
33. Dynamin-related protein DRP1 is required for mitochondrial division in mammalian cells
34. Nucleotide-dependent conformational changes in dynamin: Evidence for a mechanochemical molecular spring
35. Structural features of single amino acid repeats in proteins
36. Dynamin undergoes a GTP-dependent conformational change causing vesiculation
37. Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals
38. Generation of coated intermediates of clathrin-mediated endocytosis on protein-free liposomes
39. Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis
40. Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site
41. Functional diversity in the dynamin family
42. Multivariate statistical classification of noisy images (randomly oriented biological macromolecules)
43. Classification of very large electron microscopical image data sets
44. Use of multivariate statistics in analysing the images of biological macromolecules
45. A new generation of the IMAGIC image processing system
46. CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid
47. Disruption of a dynamin homologue affects endocytosis, organelle morphology and cytokinesis in Dictyostelium discoideum
48. Mammalian dynamin-like protein DLP1 tubulates membranes
49. Three-dimensional reconstruction of dynamin in the constricted state
50. Phragmoplastin polymerizes into spiral coiled structures via intermolecular interaction of two self-assembly domains