Poly(A) tail synthesis and regulation: Recent structural insights

Current Opinion in Structural Biology

Volumn 12, Issue 1, 2002, Pages 82-88

  Hall, Traci M Tanaka ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; MESSENGER RNA; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; SMALL NUCLEAR RIBONUCLEOPROTEIN;

3' UNTRANSLATED REGION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; REVIEW; RNA STABILITY; RNA TRANSLATION; TRANSLATION REGULATION;

EID: 0036469132     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(02)00293-2     Document Type: Review

References (48)

1. Physical and functional interactions between the mRNA cap structure and the poly(A) tail
2. The cap-to-tail guide to mRNA turnover
3. 3′-end processing of pre-mRNA in eukaryotes
4. DNA polymerase β belongs to an ancient nucleotidyltransferase superfamily
5. The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency
6. eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
7. Circularization of mRNA by eukaryotic translation initiation factors
8. Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation
9. Translational repression by a novel partner of human poly(A) binding protein, Paip2
10. Dual interactions of the translational repressor Paip2 with poly(A) binding protein
11. Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae - The prototype of the DEAD box protein family
12. Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase
13. Crystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicase
14. Cocrystal structure of the messenger RNA 5′ cap-binding protein (eIF4E) bound to 7-methyl-GDP
15. A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery
16. Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein
17. The structure and function of initiation factors in eukaryotic protein synthesis
18. Structure of yeast poly(A) polymerase alone and in complex with 3′-dATP
19. Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP
20. 2.3 Å crystal structure of the catalytic domain of DNA polymerase β
21. Structures of ternary complexes of rat DNA polymerase β, a DNA template-primer, and ddCTP
22. Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
23. Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases
24. Structure of the S15,S6,S18-rRNA complex: Assembly of the 30S ribosome central domain
25. The RNP domain: A sequence-specific RNA-binding domain involved in processing and transport of RNA
26. The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA
27. The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase
28. Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation
29. A complex secondary structure in U1A pre-mRNA that binds two molecules of U1A protein is required for regulation of polyadenylation
30. Fourteen residues of the U1 snRNP-specific U1A protein are required for homodimerization, cooperative RNA binding, and inhibition of polyadenylation
31. The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein
32. Repeating structure of cytoplasmic poly(A)-ribonucleoprotein
33. Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein
34. The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities
35. Xenopus poly(A) binding protein: Functional domains in RNA binding and protein-protein interaction
36. The Xenopus laevis poly(A) binding protein is composed of multiple functionally independent RNA binding domains
37. A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation
38. RNA recognition motif 2 of yeast Pab1p is required for its functional interaction with eukaryotic translation initiation factor 4G
39. Novel function of the eukaryotic polypeptide-chain releasing factor 3 (eRF3/GSPT) in the mRNA degradation pathway
40. Multiple portions of poly(A)-binding protein stimulate translation in vivo
41. Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro
42. Cleavage of poly(A)-binding protein by coxsackievirus 2A protease in vitro and in vivo: Another mechanism for host protein synthesis shutoff?
43. Recognition of polyadenylate RNA by the poly(A)-binding protein
44. X-ray structure of the human hyperplastic discs protein: An ortholog of the C-terminal domain of poly(A)-binding protein
45. Structure and function of the C-terminal PABC domain of human poly(A)-binding protein
46. The yeast poly(A)-binding protein Pab1p stimulates in vitro poly(A)-dependent and cap-dependent translation by distinct mechanisms
47. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
48. Raster3D: Photorealistic molecular graphics