Short term treatment with St. John's wort, hypericin or hyperforin fails to induce CYP450 isoforms in the Swiss Webster mouse

Life Sciences

Volumn 70, Issue 11, 2002, Pages 1325-1335

  Bray, B J ^a   Brennan, N J ^a   Perry, N B ^a   Menkes, D B ^a   Rosengren, R J ^a,b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

CYP1A2; CYP2E1; CYP3A; Hyperforin; Hypericin; Hypericum perforatum; St. John's wort

Indexed keywords

ALANINE AMINOTRANSFERASE; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; HYPERFORIN; HYPERICIN; HYPERICUM PERFORATUM EXTRACT;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DEMETHYLATION; DOSE RESPONSE; DRUG TOLERABILITY; DRUG TOLERANCE; ENZYME ACTIVITY; HYDROXYLATION; HYPERICUM PERFORATUM; IMMUNOBLOTTING; LIVER FUNCTION; LIVER INJURY; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; WEIGHT GAIN; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; ANTIDEPRESSIVE AGENTS; BICYCLO COMPOUNDS; BODY WEIGHT; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HYPERICUM; ISOENZYMES; LIVER; MALE; MICE; PERYLENE; PHLOROGLUCINOL; PLANT PREPARATIONS; TERPENES;

HYPERICUM; HYPERICUM PERFORATUM;

EID: 0036468848     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01499-0     Document Type: Article

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