Towards the structure of the mammalian signal recognition particle

Current Opinion in Structural Biology

Volumn 12, Issue 1, 2002, Pages 72-81

  Wild, Klemens ^a   Weichenrieder, Oliver ^b,c   Sinning, Irmgard ^a   Cusack, Stephen ^d  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DOCKING PROTEIN; RIBONUCLEOPROTEIN; RNA BINDING PROTEIN; SIGNAL RECOGNITION PARTICLE;

BINDING SITE; CRYSTAL STRUCTURE; ESCHERICHIA COLI; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN RNA BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING; REVIEW; RNA STRUCTURE; SPECIES COMPARISON;

ALU ELEMENTS; ANIMALS; BASE SEQUENCE; ESCHERICHIA COLI; MAMMALS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA; RNA, BACTERIAL; RNA-BINDING PROTEINS; SIGNAL RECOGNITION PARTICLE;

ESCHERICHIA COLI; MAMMALIA;

EID: 0036468678     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(02)00292-0     Document Type: Review

References (47)

1. The signal recognition particle
2. Binding sites of the 19-kDa and 68/72-kDa signal recognition particle (SRP) proteins on SRP RNA as determined in protein-RNA 'footprinting'
3. Disassembly and reconstitution of signal recognition particle
4. Empty site forms of the SRP54 and SR αGTPases mediate targeting of ribosome-nascent chain complexes to the endoplasmic reticulum
5. SRPDB (Signal Recognition Particle Database)
6. Structure and assembly of the Alu domain of the mammalian signal recognition particle
7. Crystal structure of the ribonucleoprotein core of the signal recognition particle
8. Crystal structure of an early protein RNA assembly complex of the signal recognition particle
9. Identification of a minimal Alu RNA folding domain that specifically binds SRP9/14
10. The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14
11. Hierarchical assembly of the Alu domain of the mammalian signal recognition particle
12. Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein
13. A truncation in the 14 kDa protein of the signal recognition particle leads to tertiary structure changes in the RNA and abolishes the elongation arrest activity of the particle
14. Elongation arrest is a physiologically important function of signal recognition particle
15. Structural requirements of Bacillus subtilis small cytoplasmic RNA for cell growth, sporulation, and extracellular enzyme production
16. Depletion of Bacillussubtilis histone-like protein, HBsu, causes defective protein translocation and induces upregulation of small cytoplasmic RNA
17. Bacillus subtilis histone-like protein, HBsu, is an integral component of a SRP-like particle that can bind the Alu domain of small cytoplasmic RNA
18. Evidence for an extended 7SL RNA structure in the signal recognition particle
19. The Alu domain homolog of the yeast signal recognition particle consists of an Srp14p homodimer and a yeast-specific RNA structure
20. Structure of the 30S ribosomal subunit
21. The complete atomic structure of the large ribosomal subunit at 2.4 Å resolution
22. Crystal structure of the Ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA
23. Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 Å resolution: Evidence for the mechanism of signal peptide binding
24. SRPrises in RNA-protein recognition
25. Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle
26. The 2Å structure of helix 6 of the human signal recognition particle
27. Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains
28. Recognition of a tetranucleotide loop of signal recognition particle RNA by protein SRP19
29. Structure of the S15, S6, S18-rRNA complex: Assembly of the 30S ribosome central domain
30. Structure of the HIV-1 nucleocapsid protein bound to the SL3 Ψ-RNA recognition element
31. Signal recognition particle components in the nucleolus
32. Determinants of a protein-induced RNA switch in the large domain of signal recognition particle identified by systematic-site directed mutagenesis
33. Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix
34. RNA tertiary interactions in the large ribosomal subunit: The A-minor motif
35. A universal mode of helix packing in RNA
36. Visualizing induced fit in early assembly of the human signal recognition particle
37. Role of SRP19 in assembly of the Archeoglobus fulgidus signal recognition particle
38. Assembly of archaeal signal recognition particle from recombinant components
39. Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor
40. Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor
41. Functional divergence of the plastid and cytosolic forms of the 54-kDa of signal recognition particle
42. Ribbons
43. Structural basis for recognition of the tra mRNA precursor by the sex-lethal protein
44. Molecular basis of double-stranded RNA-protein interactions: Structure of a dsRNA-binding domain complexed with dsRNA
45. Crystal structure of the signal sequence binding subunit of the signal recognition particle
46. MOLSCRIPT - A program to produce both detailed and schematic plots of protein structures
47. Raster3D photorealistic molecular graphics