A truncation in the 14 kDa protein of the signal recognition particle leads to tertiary structure changes in the RNA and abolishes the elongation arrest activity of the particle

Nucleic Acids Research

Volumn 25, Issue 10, 1997, Pages 1920-1929

  Thomas, Yves ^a   Bui, Nazarena ^a   Strub, Katharina ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; RNA; SIGNAL RECOGNITION PARTICLE;

ALU SEQUENCE; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; PROTEIN SYNTHESIS REGULATION; RIBOSOME; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; CONSENSUS SEQUENCE; DIMERIZATION; DOGS; ESCHERICHIA COLI; HYDROXYL RADICAL; KINETICS; MICE; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PLANTS; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, RIBOSOMAL; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION; SIGNAL RECOGNITION PARTICLE;

EID: 0030785575     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.10.1920     Document Type: Article

References (36)

1. Walter,P. and Johnson,A.E. (1994) Annu. Rev. Cell Biol., 10, 87-119.
2. Lütcke.H. (1995) Eur. J. Biochem., 228, 531-550.
3. Bovia,F. and Strub,K. (1996) J. Cell Sci., 109, 2601-2608.
4. Bacher,G., Lütcke,H., Jungnickel,B., Rapoport,T.A. and Dobberstein,B. (1996) Nature, 381, 248-251.
5. Siegel,V. and Walter,P. (1985) J. Cell Biol. 100, 1913-1921.
6. Hauser,S., Bacher,G., Dobberstein,B. and Lutcke,H. (1995) EMBO J., 14, 5485-5493.
7. Wolin,S.L. and Walter,P. (1989) J. Cell Biol., 109, 2617-2622.
8. Wolin,S.L. and Walter,P. (1988) EMBO J., 7, 3559-3569.
9. Rapoport,T.A., Heinrich,R., Walter,P. and Schulmeister,T (1987) J. Mol. Biol., 195, 621-636.
10. Powers,T. and Walter,P. (1996) Curr. Biol., 6, 331-338.
11. Ogg,S.C. and Walter,P. (1995) Cell, 81, 1075-1084.
12. Siegel,V. and Walter,P. (1986) Nature, 320, 81-84.
13. Siegel,V. and Walter,P. (1988) Cell, 52, 39-49.
14. Strub,K. and Walter,P. (1990) Mol. Cell. Biol., 10, 777-784.
15. Studier,F.W., Rosenberg,A.H., Dunn,J.J. and Dubendorff,J.W. (1990) Methods Enzymol., 185, 60-89.
16. Strub,K., Wolff,N. and Oertle,S. (1993) In Nierhaus,K.H., Franceschi,F. Subramanian,A.R., Erdmann,V.A. and Wittmann-Liebold,B. (ed.), The Translational Apparatus. Plenum Press, New York, NY, pp. 635-645.
17. Bovia,F. Wolff,N., Ryser,S. and Strub,K. (1997) Nucleic Acids Res., 25, 318-325.
18. Lingelbach,K., Zwieb,C., Webb,J.R., Marshallsay,C., Hoben,P.J., Walter,P. and Dobberstein,B. (1988) Nucleic Acids Res., 16, 9431-9442.
19. Strub,K., Moss,J. and Walter,P. (1991) Mol. Cell. Biol. 11, 3949-3959.
20. Walter,P. and Blobel,G. (1983) Methods Enzymol., 96, 84-93.
21. Belin,D., Bost,S., Vassalli,J.-D. and Strub,K. (1996) EMBO J., 15, 468-478.
22. Bovia,F, Bui,N. and Strub,K. (1994) Nucleic Acids Res., 22, 2028-2035.
23. Strub,K. and Walter,P. (1989) Proc. Natl. Acad. Sci. USA, 86, 9747-9751.
24. Bovia,F., Fornallaz,M., Leffers,H. and Strub,K. (1995) Mol. Biol. Cell, 6, 471-484.
25. Walter,P. and Blobel,G. (1983) Cell, 34, 525-533.
26. Wiedmann,B., Sakai,H., Davis,T.A. and Wiedmann,M. (1994) Nature, 370, 434-440.
27. Latham,J.A. and Cech,T.R. (1989) Science, 245, 276-282.
28. Lentzen,G., Moine,H., Ehresmann,C., Ehresmann,B. and Wintermeyer,W. (1996) RNA, 2, 244-253.
29. Stern,S., Moazad,D. and Noller,H.F. (1988) Methods Enzymol., 164, 481-489.
30. Siegel,V. and Walter,P. (1988) EMBO J., 7, 1769-1775.
31. Birse,D.E.A., Kapp,U., Strub,K., Cusack,S. and Åberg,A. (1997) EMBO J., in press.
32. Zwieb,C., Müller,F. and Larsen,N. (1996) Folding Design, 1, 315-324.
33. Zwieb,C. (1985) Nucleic Acids Res., 13, 6105-6124.
34. Walter,P. and Lingappa,V.R. (1986) Annu. Rev. Cell Biol., 2, 499-516.
35. Brown,J.D., Hann,B.C, Medzihradszky,K.F., Niwa,M., Burlingame,A.L. and Walter,P. (1994) EMBO J., 13, 4390-4400.
36. Bui,N., Wolff,N., Cusack,S. and Strub,K., RNA, in press.