TNF-α potentiates C5a-stimulated eosinophil adhesion to human bronchial epithelial cells: A role for α5β1 integrin

Journal of Immunology

Volumn 168, Issue 3, 2002, Pages 1380-1388

  Burke Gaffney, Anne ^a   Blease, Kate ^a   Hartnell, Adele ^a   Hellewell, Paul G ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5A; INTEGRIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASTHMA; BRONCHUS MUCOSA; CELL ADHESION; CONTROLLED STUDY; CROSS LINKING; EOSINOPHIL; EPITHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL;

EID: 0036467352     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.3.1380     Document Type: Article

References (69)

1. Epidemiology of asthma: The year in review
2. Eosinophils in asthma
3. The role of eosinophils in the pathogenesis of asthma
4. Eosinophilia
5. Pharmacology of the eosinophil
6. Mechanisms of eosinophil activation
7. Eosinophil degranulation in the presence of bronchial epithelial cells: Effect of cytokines and role of adhesion
8. Effects of human lung fibroblasts on eosinophil degranulation
9. Regulation of the release of eosinophil cationic protein by eosinophil adhesion
10. Airway-eosinophilic inflammation and bronchial hyperresponsiveness after allergen inhalation challenge in asthma
11. Adhesion of activated eosinophils to respiratory epithelial cells is enhanced by tumor necrosis factor-α and interleukin-1β
12. Respiratory syncytial virus infection enhances neutrophil and eosinophil adhesion to cultured respiratory epithelial cells: Roles of CD18 and intercellular adhesion molecule-1
13. Phenotyping and cytokine regulation of the BEAS-2B human bronchial epithelial cell: Demonstration of inducible expression of the adhesion molecules VCAM-1 and ICAM-1
14. A CD18/ICAM-1-dependent pathway mediates eosinophil adhesion to human bronchial epithelial cells
15. Mechanisms and regulation of polymorphonuclear leukocyte and eosinophil adherence to human airway epithelial cells
16. 1, very late activation antigen-6) on human eosinophils
17. Freezing adhesion molecules in a state of high-avidity binding blocks eosinophil migration
18. 2 integrin avidity by chemoattractants in eosinophils
19. Airway epithelial integrins: Why so many?
20. Complement fragments
21. Effect of exercise on complement activity
22. ELISA of complement C3a in bronchoalveolar lavage fluid
23. Identification of neutrophil chemotactic factors in bronchoalveolar lavage fluid of asthmatic patients
24. Guinea pigs with a natural C3a-receptor defect exhibit decreased bronchoconstriction in allergic airway disease: Evidence for an involvement of the C3a anaphylatoxin in the pathogenesis of asthma
25. A role for the C3a anaphylatoxin receptor in the effector phase of asthma
26. Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma
27. Role of chemokines in asthmatic airway inflammation
28. Eosinophil priming by cytokines: From cellular signal to in vivo modulation
29. Effects of interleukin (IL)-3 and IL-5 on human eosinophil degranulation induced by complement components C3a and C5a
30. Chemokine and cytokine cooperativity: Eosinophil migration in the asthmatic response
31. Augmentation of stimulated eosinophil degranulation by VLA-4 (CD49d)-mediated adhesion to fibronectin
32. Eosinophil adhesion to vascular cell adhesion molecule-1 activates superoxide anion generation
33. Cytokines as mediators of chronic asthma
34. Priming differentially regulates neutrophil adhesion molecule expression/function
35. Activation dependent and independent VLA-4 binding sites on vascular cell adhesion molecule-1
36. Modulation of phenotypic and functional properties of human peripheral blood monocytes by IL-4
37. 4/180 formation
38. Regulation of ICAM-1 by dexamethasone in a human vascular endothelial cell line EAhy926
39. CD66-dependent neutrophil activation: A possible mechanism for vascular selectin-mediated regulation of neutrophil adhesion
40. Regulation of polymorphonuclear neutrophil CD16 and CD11b/CD18 expression by matrix proteins during hypoxia is VLA-5, VLA-6 dependent
41. Eotaxin stimulates eosinophil adhesion to human lung microvascular endothelial cells
42. Eotaxin induces a sustained reduction in the functional adhesive state of very late antigen 4 for the connecting segment 1 region of fibronectin
43. Chemokines induce eosinophil degranulation through CCR-3
44. Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogenactivated protein kinases
45. Eosinophils maintain their capacity to signal and release eosinophil cationic protein upon repetitive stimulation with the same agonist
46. Eosinophil tethering to interleukin-4-activated endothelial cells requires both P-selectin and vascular cell adhesion molecule-1
47. Integrins take partners: Cross-talk between integrins and other membrane receptors
48. Integrin-mediated signaling in human neutrophil functioning
49. Integrins and signal transduction
50. Very late antigen-5 and complement receptor type 3 cooperatively mediate the interaction between Bordetella pertussis and human monocytes
51. 1 signaling pathways
52. + cells from cord blood to fibronectin is associated with the PI-3 kinase pathway
53. Induction of neutrophil respiratory burst by tumor necrosis factor-α: Priming effect of solid-phase fibronectin and intervention of CD11b-CD18 integrins
54. Cross-linking of CD18 primes human neutrophils for activation of the respiratory burst in response to specific stimuli: Implications for adhesion-dependent physiological responses in neutrophils
55. "Outside-in" signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils
56. In vivo priming of FcαR functioning on eosinophils of allergic asthmatics
57. 1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway
58. An improved method for the isolation of eosinophilic granulocytes from peripheral blood of normal individuals
59. T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density
60. Comparison of human eosinophil and neutrophil adhesion to endothelial cells under nonstatic conditions: Role of L-selectin
61. Cellular and biochemical characteristics of bronchoalveolar lavage fluid in symptomatic nonallergic asthma
62. Fibronectins
63. Segmental antigen challenge increases fibronectin in bronchoalveolar lavage fluid
64. Adhesion mechanisms involved in C5a-induced eosinophil homotypic aggregation
65. Fibronectin and its receptors
66. 1 (VLA-4, CD49d/CD29)
67. 1 (VLA-4)
68. Human eosinophils preferentially survive on tissue fibronectin compared with plasma fibronectin
69. VLA-4 and VLA-5 are required for leukocyte accumulation in the lungs of antigen-challenged mice