The genetic basis for psychiatric illness in man

European Journal of Neuroscience

Volumn 16, Issue 3, 2002, Pages 403-407

  Tandon, Kopal ^a   McGuffin, Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOPTION; ALLELE; BEHAVIOR; CONFERENCE PAPER; ENVIRONMENT; FAMILY; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC LINKAGE; HERITABILITY; HUMAN; INHERITANCE; MEDICAL RESEARCH; MENTAL DISEASE; MOLECULAR GENETICS; PERSONALITY; PRIORITY JOURNAL; TWINS;

CHROMOSOME MAPPING; DNA MUTATIONAL ANALYSIS; GENE FREQUENCY; GENETIC SCREENING; HUMANS; MENTAL DISORDERS; MOLECULAR BIOLOGY;

EID: 0036460105     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2002.02095.x     Document Type: Conference Paper

References (37)

1. Arranz, M.J., Munro, J., Birkett, J., Bolonna, A., Mancama, D., Sodhi, M., Lesch, K.P., Meyer, J.F., Sham, P., Collier, D., Murray, R.M. & Kerwin, R.W. (2000) Pharmacogenetic prediction of clozapine response. Lancet, 355, 1615-1616.
2. Bailey, A., Phillips, W. & Rutter, M. (1996) Autism: Towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives. J. Child Psychol. Psychiatry, 37, 89-126.
3. Bouchard, T.J. (1998) Genetic and environmental influences on adult intelligence and special mental abilities. Hum. Biol., 70, 257-280.
4. Cardon, L.R., Smith, S.D., Fulker, D.W., Kimberling, W.J., Pennington, B.F. & DeFries, J.C. (1994) Quantitative trait locus for reading disability on chromosome 6. Science, 266, 276-279.
5. Corder, E.H., Saunders, A.M., Strittmatter, W.J., Schmechel, D.E., Gaskell, P.C., Small, G.W., Roses, A.D., Haines, J.L. & Pericak-Vance, M.A. (1993) Gene dose of apolipoprotien E type 4 allele and the risk of Alzheimer's disease in late onset families. Science, 261, 921-923.
6. Craddock, N. & Jones, I. (1999) Genetics of bipolar disorder. J. Med. Genet., 36, 585-594.
7. Craddock, N., Khodel, V., Van Eerdewegh, P. & Reich, T. (1995) Mathematical limits of multilocus models: The genetic transmission of bipolar disorder. Am. J. Hum. Genet., 57, 690-702.
8. Daniels, J., Holmans, P., Williams, N., Turic, D., McGuffin, P., Plomin, R. & Owen, M.J. (1998) A simple method for analyzing microsatellite allelic image patterns generated from DNA pools and its application to allelic association studies. Am. J. Hum. Genet., 62, 1189-1197.
9. Edwards, J.H. (1960) The simulation of Mendelism. Acta Genetica, 10, 63-70.
10. Falconer, D.S. (1965) The inheritance of liability to certain diseases, estimated from evidence among relatives. Ann. Hum. Genet., 29, 51-76.
11. Farmer, A., Harris, T., Redman, K., Sadler, S., Mahmood, A. & McGuffin, P. (2000) The Cardiff Depression Study- A sib pair study of life events and familiality in major depression. Br. J. Psychiatry, 176, 150-155.
12. Farmer, A., Scourfield, J., Martin, N., Cardno, A. & McGuffin, P. (1999) Is disabling fatigue in childhood influenced by genes? Psychol. Med., 29, 279-282.
13. Fischer, P.J., Turic, D., Williams, N.M., McGuffin, P., Asherson, P., Ball, D., Craig, I., Eley, T., Hill, L., Chorney, K., Chorney, M.J., Benbow, C.P., Lubinski, D., Plomin, R. & Owen, M.J. (1999) DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children. Hum. Mol. Genet., 8, 915-922.
14. Heston, L.L. (1966) Psychiatric disorders in foster home reared children of schizophrenia mothers. Br. J. Psychiatry, 112, 819-825.
15. Jones, I., Kent, L. & Craddock, N. (2002) Genetics of affective disorders. In McGuffin, P., Owen, M.J. & Gottesman, I.I. (eds), Psychiatric Genetics and Genomics. Oxford University Press, Oxford, pp. 211-246.
16. Kendler, K.S., MacLean, C.J., Ma, Y., O'Neill, F.A., Walsh, D. & Straub, R.E. (1999) Marker-to-marker linkage disequilibrium on chromosome 5q, 6p, and 8p in Irish high-density schizophrenia pedigrees. Am. J. Med. Genet., 88, 29-33.
17. Kendler, K.S., Neale, M., Kessler, R., Heath, A. & Eaves, L. (1993) A twin study of recent life events and difficulties. Arch. Gen. Psychiatry, 50, 789-796.
18. Kety, S.S. (1983) Mental illness in the biological and adoptive relatives of schizophrenia adoptees. Findings relevant to genetic and environmental factors in etiology. Am. J. Psychiatry, 140, 720-727.
19. Kety, S.S., Wender, P.H., Jacobson, B., Ingraham, L.J., Jansson, L., Faber, B. & Kinney, D.K. (1994) Mental illness in the biological and adoptive relatives of schizophrenia adoptees. Replication of the Copenhagen Study in the rest of Denmark. Arch. Gen. Psychiatry, 51, 442-455.
20. Lander, E.S. & Schork, N. (1994) Genetic dissection of complex traits. Science, 265, 2037-2048.
21. Liddell, M.B., Lovestone, S. & Owen, M.J. (2001) Genetic risk of Alzheimer's disease: Advising relatives. Br. J. Psychiatry, 178, 7-11.
22. McGuffin, P. & Huckle, P. (1990) Simulation of Mendelism revisted: The recessive gene for attending Medical School. Am. J. Hum. Genet., 46, 994-999.
23. McGuffin, P., Katz, R., Watkins, S. & Rutherford, J. (1996) A hospital-based twin register of the heritability of DMS-VI unipolar depression. Arch. Gen. Psychiatry, 53, 129-136.
24. McGuffin, P., Owen, M.J. & Farmer, A.E. (1995) Genetic basis of schizophrenia. Lancet, 346, 678-682.
25. McGuffin, P., Riley, B. & Plomin, R. (2001) Toward behavioural genomics. Science, 291, 1232-1249.
26. O'Rourke, D.H., Gottesman, I.I., Suarez, B.K., Rice, J. & Reich, T. (1982) Refutation of the general single-locus model for the etiology of schizophrenia. Am. J. Hum. Genet., 34, 630-649.
27. Owen, M., O'Donovan, M. & Gottesman, I. (2002) Schizophrenia. In McGuffin, P., Owen, M.J. & Gottesman, I.I. (eds), Psychiatric Genetics and Genomics. Oxford University Press, Oxford, pp. 247-266.
28. Plomin, R., DeFries, J., McClearn, G. & McGuffin, P. (2001) Behavioural Genetics, 4th Edn. Freeman, San Francisco.
29. Risch, N. & Merikangas, K. (1996) The future of genetic studies of complex human diseases. Science, 273, 1516-1517.
30. Rutherford, J., McGuffin, P., Katz, R.J. & Murray, R.M. (1993) Genetic influences on eating attitudes in a normal female twin population. Psychol. Med., 23, 425-436.
31. Schulte-Korne, G., Grimm, T., Nothen, M.M., Muller-Myhsok, B., Cichon, S., Vogt, I.R., Propping, P. & Remschmidt, H. (1998) Evidence for linkage of spelling disability to chromosome 15. Am. J. Hum. Genet., 63, 279-282.
32. Spielman, R.S. & Ewens, W.J. (1996) The TDT and other family-based tests for linkage disequilibrium and association. Am. J. Hum. Genet., 59, 983-989.
33. Sullivan, P.F., Neale, M. & Kendler, K.S. (2000) Genetic epidemiology of major depression: Review and meta-analysis. Am. J. Psychiatry, 157, 1552-1562.
34. Thapar, A. (2002) Childhood disorders. In McGuffin, P., Owen, M.J. & Gottesman, I.I. (eds), Psychiatric Genetics and Genomics. Oxford University Press Ltd., Oxford, pp. xxx-xxx.
35. Thapar, A., Harrington, R., Ross, K. & McGuffin, P. (2000) Does the definition of ADHD affect heritability? J. Am. Acad. Child Adolesc. Psychiatry, 39, 1528-1536.
36. Williams, J. (2002) Language disorders. In McGuffin, P., Owen, M.J. & Gottesman, I.I. (eds), Psychiatric Genetics and Genomics. Oxford University Press, Oxford, pp. 129-146.
37. Williams, J., McGuffin, P., Nothen, M. & Owen, M.J. (1997) Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia. Lancet, 349, 1221.