Cloning and functional characterization of two glycine receptor α-subunits from the perch retina

European Journal of Neuroscience

Volumn 16, Issue 1, 2002, Pages 69-80

  Gisselmann, G ^a   Galler, A ^a   Friedrich, F ^a   Hatt, H ^a   Bormann, J ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

CDNA; Fish; Inhibition; Ion channel; Patch clamp

Indexed keywords

GLYCINE RECEPTOR; GLYCINE RECEPTOR ALPHA1; GLYCINE RECEPTOR ALPHA2; RECEPTOR SUBUNIT; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; MAMMAL; MOLECULAR CLONING; NONHUMAN; PERCH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN VARIANT; RECEPTOR AFFINITY; RETINA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SEQUENCE HOMOLOGY; SPINAL CORD; TISSUE DISTRIBUTION; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; BRAIN CHEMISTRY; CLONING, MOLECULAR; ELECTROPHYSIOLOGY; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLYCINE; GLYCINE AGENTS; MOLECULAR SEQUENCE DATA; PERCHES; PICROTOXIN; RECEPTORS, GLYCINE; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPINAL CORD; STRYCHNINE; TAURINE;

EID: 0036455147     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2002.02070.x     Document Type: Article

References (49)

1. Akagi, N., Hirai, K. & Hishinuma, F. (1991) Cloning of a glycine receptor subtype expressed in rat brain and spinal cord during a specific period of neuronal development. FEBS Lett., 281, 160-166.
2. Baev, K.V., Rusin, K.I. & Safronov, B.V. (1992) Primary receptor for inhibitory transmitters in lamprey spinal cord neurons. Neuroscience, 46, 931-941.
3. Betz, H. (1992) Structures and function of inhibitory glycine receptors. Quart. Rev. Biophys., 25, 381-394.
4. Betz, H., Kuhse, J., Schmieden, V., Laube, B., Kirsch, J. & Harvey, R.J. (1999) Structure and functions of inhibitory and exitatory glycine receptors. Ann. NY Acad. Sci. USA, 868, 667-676.
5. Bormann, J. (1990) Patch-clamp studies of glycine-gated chloride channels. In O. P. Ottersen & J. Storm-Mathisen. (eds), Glycine Neurotransmission. Wiley, Chichester, UK, pp. 111-137.
6. Bormann, J., Hamill, O.P. & Sakmann, B. (1987) Mechanism of anion permeation through channels gated by glycine and γ-aminobutyric acid in mouse cultured spinal neurones. J. Physiol. (London), 385, 243-286.
7. Bormann, J., Rundström, N., Betz, H. & Langosch, D. (1993) Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers. EMBO J., 12, 3729-3737.
8. Brünig, I., Sommer, M., Hatt, H. & Bormann, J. (1999) Dopamine receptor subtypes modulate olfactory bulb γ-aminobutyric acid type A receptors. Proc. Natl. Acad. Sci. USA, 96, 2456-2460.
9. Chalfie, M., Tu, Y., Euskirchen, G., Ward, W.W. & Prasher, D.C. (1994) Green fluorescent protein as a marker for gene expression. Science, 263, 802-805.
10. David-Watine, B., Goblet, C., De Saint Jan, D., Fucile, S., Devignot, V., Bregestovski, P. & Korn, H. (1999) Cloning, expression and electrophysiological characterization of glycine receptor α-subunit from zebrafish. Neuroscience, 90, 303-317.
11. De Saint Jan, D., David-Watine, B., Korn, H. & Bregestovski, P. (2001) Activation of human α1 and α2 homomeric glycine receptors by taurine and GABA. J. Physiol. (Lond.), 535, 741-755.
12. Enz, R. & Bormann, J. (1995) Expression of glycine receptor subunits and gephyrin in single bipolar cells of the rat retina. Vis. Neurosci., 12, 501-507.
13. Fucile, S., De Saint Jan, D., David-Watine, B., Korn, H. & Bregestovski, P. (1999) Comparison of glycine and GABA actions on the zebrafish homooligomeric glycine receptor. J. Physiol. (Lond.), 517, 369-383.
14. A receptors in the rabbit retina. Cell Tiss. Res., 276, 295-307.
15. Grenningloh, G., Rienitz, A., Schmitt, B., Methfessel, C., Zensen, M., Beyreuther, K., Gundelfinger, E.D. & Betz, H. (1987) The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors. Nature, 328, 215-220.
16. 1-glycine receptor channel-opening kinetics in the submillisecond time domain. Biophys. J., 77, 727-738.
17. Imboden, M., De Saint Jan, D., Leulier, F., Korn, H., Goblet, C. & Bregestovski, P. (2001a) Isolation and charactrization of an alpha 2-type zebrafish glycine receptor subunit. Neuroscience, 103, 799-810.
18. Imboden, M., Devignot, V., Korn, H. & Goblet, C. (2001b) Regional distribution of glycine receptor messenger RNA in the central nervous system of the zebrafish. Neuroscience, 103, 811-830.
19. Imboden, M., Devignot, V. & Goblet, C. (2001c) Phylogenetic relationship and chromosomal location of five distinct glycine receptor subunit genes in the teleost Danio rerio. Dev. Genes Evol., 211, 415-422.
20. Karschin, A. & Wässle, H. (1990) Voltage- and transmitter-gated currents in isolated rod bipolar cells of rat retina. J. Neurophysiol., 63, 860-876.
21. Kuhse, J., Betz, H. & Kirsch, J. (1995) The inhibitory glycine receptor: Architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex. Curr. Opin. Neurobiol., 5, 318-323.
22. Kuhse, J., Kuryatov, A., Maulet, Y., Malosio, M.L., Schmieden, V. & Betz, H. (1991) Alternative splicing generates two isoforms of the α2 subunit of the inhibitory glycine receptor. FEBS Lett., 283, 73-77.
23. Kuhse, J., Schmieden, V. & Betz, H. (1990) Identification and functional expression of a novel ligand binding subunit of the inhibitory glycine receptor. J. Biol. Chem., 265, 22317-22320.
24. Langosch, D., Thomas, L. & Betz, H. (1988) Conserved quaternary structure of ligand-gated ion channels: The postsynaptic glycine receptor is a pentamer. Proc. Natl. Acad. Sci. USA, 85, 7394-7398.
25. Legendre, P. (1998) A reluctant gating mode of glycine receptor channels determines the time course of inhibitory miniature synaptic events in zebrafish hindbrain neurons. J. Neurosci., 18, 2856-2870.
26. Lewis, T.M., Sivilotti, L.G., Colquhoun, D., Gardiner, R.M., Schoepfer, R. & Rees, M. (1998) Properties of human glycine receptors containing the hyperekplexia mutation α1 (K276E), expressed in Xenopus oocytes. J. Physiol. (Lond.), 507, 25-40.
27. Lynch, J.W., Han, N.L., Haddrill, J., Pierce, K.D. & Schofield, P.R. (2001) The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state. J. Neurosci., 21, 2589-2599.
28. Malosio, M.L., Marqueze Pouey, B., Kuhse, J. & Betz, H. (1991) Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain. EMBO J., 10, 2401-2409.
29. Marc, R.E., Murry, R.F. & Basinger, S.F. (1995) Pattern recognition of amino acid signatures in retinal neurons. J. Neurosci., 15, 5106-5129.
30. Marshall, R.D. (1972) Glycoproteins. Annu. Rev. Biochem., 41, 673-702.
31. Matzenbach, B., Maulet, Y., Sefton, L., Courtier, B., Avner, P., Guénet, J.-L. & Betz, H. (1994) Structural analysis of mouse glycine receptor a subunit genes. Identification and chromosomal localization of a novel variant, α4. J. Biol. Chem., 269, 2607-2612.
32. Pierce, K.D., Handford, C.A., Morris, R., Vafa, B., Dennis, J.A., Healy, P.J. & Schofield, P.R. (2001) A nonsense mutation in the alpha1 subunit of the inhibitory glycine receptor associated with bovine myoclonus. Mol. Cell. Neurosci., 17, 354-363.
33. Pribilla, I., Takagi, T., Langosch, D., Bormann, J. & Betz, H. (1992) The atypical M2 segment of the β subunit confers picrotoxinin resistance to inhibitory glycine receptor channels. EMBO J., 11, 4305-4311.
34. C and ρ subunit receptors from white perch retina. Vis. Neurosci., 14, 843-851.
35. Rajendra, S., Lynch, J.W. & Schofield, P.R. (1997) The glycine receptor. Pharmacol. Ther., 73, 121-146.
36. Rajendra, S., Vandenberg, R.J., Pierce, K.D., Cunningham, A.M., French, P.W., Barry, P.H. & Schofield, P.R. (1995) The unique extracellular disulfide loop of the glycine receptor is a principal ligand-binding element. EMBO J., 14, 2987-2998.
37. Ruiz-Gomez, A., Vaello, M.L., Valdivieso, F. & Mayor, F. Jr (1991) Phosphorylation of the 48-kDa subunit of the glycine receptor by protein kinase C. J. Biol. Chem., 266, 559-566.
38. Rundström, N., Schmieden, V., Betz, H., Bormann, J. & Langosch, D. (1994) Cyanotriphenylborate: Subtype-specific blocker of glycine receptor chloride channels. Proc. Natl. Acad. Sci. USA, 91, 8950-8954.
39. Sivilotti, L. & Nistri, A. (1991) GABA receptor mechanisms in the central nervous system. Prog. Neurobiol., 36, 35-92.
40. Sontheimer, H., Becker, C.M., Pritchett, D.B., Schofield, P.R., Grenningloh, G., Kettenmann, H., Betz, H. & Seeburg, P.H. (1989) Functional chloride channels by mammalian cell expression of rat glycine receptor subunit. Neuron, 2, 1491-1497.
41. Stroud, R.M., McCarthy, M.P. & Shuster, M. (1990) Nicotinic acetylcholine receptor superfamily of ligand-gated ion channels. Biochemistry, 50, 11009-11023.
42. Thompson, J.D., Gibson, T.J., Plewniak, F., Jeanmougin, F. & Higgins, D.G. (1997) The ClustalX windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucl. Acids Res., 24, 4876-4882.
43. Vandenberg, R.J., French, R.J., Barry, P.H., Shine, J. & Schofield, P.R. (1992b) Antagonism of ligand-gated ion channel receptors: Two domains of the glycine receptor α subunit form the strychnine-binding site. Proc. Natl. Acad. Sci. USA, 89, 1765-1769.
44. Vandenberg, R.J., Handford, C.A. & Schofield, R. (1992a) Distinct agonist- and antagonist-binding sites on the glycine receptor. Neuron, 9, 491-496.
45. Wässle, H., Koulen, P., Brandstätter, J.H., Fletcher, E.L. & Becker, C.-M. (1998) Glycine and GABA receptors in the mammalian retina. Vision Res., 38, 1411-1430.
46. Wellerdieck, C., Oles, M., Pott, L., Korsching, S., Gisselmann, G. & Hatt, H. (1997) Functional expression of odorant receptors of the zebrafish Danio rerio and of the nematode C. elegans in HEK293 cells. Chem. Senses, 22, 467-476.
47. A receptor channel-lining residues probed with cysteine mutants. Biophys. J., 69, 1858-1867.
48. Zhorov, B.S. & Bregestovski, P.D. (2000) Chloride channels of glycine and GABA receptors with blockers: Monte Carlo minimization and structure-activity relationships. Biophys. J., 78, 1786-1803.
49. Zufall, F., Hatt, H. & Firestein, S. (1993) Rapid application and removal of second messengers to cyclic nucleotide-gated channels from olfactory epithelium. Proc. Natl. Acad. Sci. USA, 90, 9335-9339.