Developmental and food-access-dependent changes in effector systems activated by leptin

Pflugers Archiv European Journal of Physiology

Volumn 445, Issue 3, 2002, Pages 366-374

  Eiden, Sandra ^a   Doering, Heiko ^a   Schmidt, Ingrid ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Body composition; Food intake; Juvenile rats; Metabolic cold defense; Mice

Indexed keywords

FAT; LEPTIN;

AGE; ANIMAL EXPERIMENT; ARTICLE; BODY FAT; BODY WEIGHT; CONTROLLED STUDY; DEVELOPMENT; DIET RESTRICTION; FEEDING; FEMALE; FOOD INTAKE; MALE; METABOLIC RATE; NONHUMAN; PERINATAL PERIOD; PHYSIOLOGY; PRIORITY JOURNAL; RAT; TIME; ADIPOSE TISSUE; AGING; ANIMAL; ANIMAL FOOD; ANIMAL HUSBANDRY; BODY COMPOSITION; DRUG EFFECT; EATING; FOOD DEPRIVATION; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; METABOLISM; MOUSE; MOUSE STRAIN; NEWBORN; ORGAN SIZE; SUCKLING; WEANING; ZUCKER RAT;

ADIPOSE TISSUE; AGING; ANIMAL FEED; ANIMAL HUSBANDRY; ANIMALS; ANIMALS, NEWBORN; ANIMALS, SUCKLING; BODY COMPOSITION; EATING; FEMALE; FOOD DEPRIVATION; LEPTIN; MALE; MICE; MICE, INBRED STRAINS; ORGAN SIZE; RATS; RATS, ZUCKER; WEANING;

EID: 0036453605     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0944-4     Document Type: Article

References (35)

1. Ahima RS, Kelly J, Elmquist JK, Flier JS (1999) Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology 140:4923-4931
2. Buchberger P, Schmidt I (1996) Is the onset of obesity in suckling fa/fa rats linked to a potentially larger milk intake? Am J Physiol 271:R472-R476
3. Doering H (2000) Wirkung von Rekombinantem Leptin auf den Energiehaushalt von Mäusen in Abhängigkeit vom Nahrungsangebot. Dissertation, University of Marburg
4. Doering H, Schwarzer K, Nuesslein-Hildesheim B, Schmidt I (1998) Leptin selectively increases energy expenditure of food-restricted lean mice. Int J Obes Relat Metab Disord 22:83-88
5. Eiden S, Preibisch G, Schmidt I (2001) Leptin responsiveness of juvenile rats: Proof of leptin function within the physiological range. J Physiol (Lond) 530:131-139
6. Elmquist JK, Elias CF, Saper CB (1999) From lesions to leptin: Hypothalamic control of food intake and body weight. Neuron 22:221-232
7. Halaas JL, Boozer C, Blair-Wets J, Fidahusein N, Denton DA, Friedman JM (1997) Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc Natl Acad Sci USA 94:8878-8883
8. Harris RBS, Zhou J, Redmann SM Jr, Smagin GN, Smith SR, Rodgers E, Zachwieja JJ (1998) A leptin dose-response study in obese (ob/ob) and lean (+/?) mice. Endocrinology 139:8-19
9. Haynes WG, Morgan DA, Walsh SA, Mark AL, Sivitz WI (1997) Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest 100:270-278
10. Himms-Hagen J (1999) Physiological roles of the leptin endocrine system: Differences between mice and humans. Crit Rev Clin Lab Sci 36:575-655
11. Hwa JJ, Fawzi AB, Graziano MP, Ghibaudi LG, Williams P, Van Heek M, Davis H, Rudinski M, Sybertz E, Strader CD (1997) Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice. Am J Physiol 272:R1204-R1209
12. Kaul R, Schmidt I, Carlisle HJ (1985) Maturation of thermoregulation in Zucker rats. Int J Obes Relat Metab Disord 9:401-409
13. Kaul R, Heldmaier G, Schmidt I (1990) Defective thermoregulatory thermogenensis does not cause onset of obesity in Zucker rats. Am J Physiol 259:E11-E18
14. Kennedy GC (1953) The role of depot fat in the hypothalamic control of food intake in the rat. Proc R Soc Lond Ser B 140:578-592
15. Kowalski TJ, Houpt TA, Jahng J, Okada N, Chua SC Jr, Smith GP (1998) Ontogeny of neuropeptide Y expression in response to deprivation in lean Zucker rat pups. Am J Physiol 275:R466-R470
16. Kraeft S, Schwarzer K, Eiden S, Nuesslein-Hildesheim B, Preibisch G, Schmidt I (1999) Leptin responsiveness and gene dosage for leptin receptor mutation (fa) in newborn rats. Am J Physiol 276:E836-E842
17. Leveille GH, O'Hea EK (1967) Influence of periodicity of eating on energy metabolism in the rat. J Nutr 93:541-545
18. Levin N, Nelson C, Gurney A, Vandlen R, De Sauvage F (1996) Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc Natl Acad Sci USA 93:1726-1730
19. Markewicz B, Kuhmichel G, Schmidt I (1993) Onset of excess fat deposition in Zucker rats with and without decreased thermogenesis. Am J Physiol 265:E478-E486
20. Martinez V, Barrachina MD, Wang L, Taché Y (1999) Intracerebroventricular leptin inhibits gastric emptying of a solid nutrient meal in rats. Neuroreport 10:3217-3221
21. Meierfrankenfeld B, Abelenda M, Jauker H, Klingenspor M, Kershaw EE, Chua SC Jr, Leibel RL, Schmidt I (1996) Perinatal energy stores and excessive fat deposition in genetically obese (fa/fa) rats. Am J Physiol 270:E700-E708
22. Mistry AM, Swick AG, Romsos DR (1997) Leptin rapidly lowers food intake and elevates metabolic rates in lean and ob/ob mice. J Nutr 127:2065-2072
23. Mistry AM, Swick A, Romsos DR (1999) Leptin alters metabolic rates before acquisition of its anorectic effect in developing neonatal mice. Am J Physiol 277:R742-747
24. Müller G, Ertl J, Gerb M, Preibisch G (1997) Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J Biol Chem 272:10585-10593
25. Nuesslein-Hildesheim B, Schmidt I (1994) Is the circadian core temperature rhythm of juvenile rats due to a periodic blockade of thermoregulatory thermogenesis? Pflugers Arch 427:450-454
26. Pelleymounter MA (1997) Leptin and the physiology of obesity. Curr Pharm Des 3:85-98
27. Pelleymounter MA, Cullen MJ, Healy D, Hecht R, Winters D, McCaleb M (1998) Efficacy of exogenous recombinant murine leptin in lean and obese 10- to 12-mo-old female CD-1 mice. Am J Physiol 275:R950-R959
28. Scarpace PJ, Matheny M, Moore RL, Tumer N (2000) Impaired leptin responsiveness in aged rats. Diabetes 49:431-435
29. Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG (2000) Central nervous system control of food intake. Nature 404:661-671
30. Schwarzer K, Doering H, Schmidt I (1997) Different physiological traits underlying increased body fat of fatty (fa/fa) and heterozygous (+/fa) rats. Am J Physiol 272:E100-E106
31. Stehling O, Doering H, Ertl J, Preibisch G, Schmidt I (1996) Leptin reduces juvenile fat stores by altering the circadian cycle of energy expenditure. Am J Physiol 271:R1770-R1774
32. Stehling O, Doering H, Nuesslein-Hildesheim B, Olbort M, Schmidt I (1997) Leptin-doses halving the body fat of lean pups are not effective in genetically obese (fa/fa) rat pups. In: Blum WF, Kiess W, Rascher W (eds) Leptin - The Voice of the Adipose Tissue. Barth, Heidelberg, pp 140-147
33. Stehling O, Döring H, Nuesslein-Hildesheim B, Olbort M, Schmidt I (1997) Leptin does not reduce body fat content but augments cold defense abilities in thermoneutrally reared rat pups. Pflugers Arch 434:694-697
34. Trayhurn P, Milner RE (1989) A commentary on the interpretation of in vitro biochemical measures of brown adipose tissue thermogenesis. Can J Physiol Pharmacol 67:811-819
35. Truett GE, Tempelman RJ, Walker JA (1995) Codominant effects of the fatty (fa) gene during early development of obesity. Am J Physiol 268:E15-E20