Perinatal energy stores and excessive fat deposition in genetically obese (fa/fa) rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 270, Issue 4 33-4, 1996, Pages

  Meierfrankenfeld, Birgit ^b   Abelenda, Maria ^b   Jauker, Heike ^b   Klingenspor, Martin ^b   Kershaw, Erin E ^b   Chua Jr , Streamson C ^b   Leibel, Rudolph L ^b   Schmidt, Ingrid ^b  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b NONE

Author keywords

adipose tissue; body composition; glycogen; insulin; newborn; Zucker rat x Brown Norway hybrids

Indexed keywords

GLYCOGEN; INSULIN; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CARCASS; CROSS BREEDING; ENERGY METABOLISM; FEMALE; GENOTYPE; INSULIN BLOOD LEVEL; LIPID STORAGE; LIVER; MALE; NONHUMAN; OBESITY; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; RAT;

EID: 0029881465     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.270.4.e700     Document Type: Article

References (31)

1. Atef, N., C. Brule, M.-T. Bihoreau, A. Ktorza, L. Picon, and L. Penicaud. Enhanced insulin secretory response to acetylcholine by perifused pancreas of 5-day-old preobese Zucker rats. Endocrinology 129: 2219-2224, 1991.
2. Bazin, R., D. Etéve, and M. Lavau. Evidence for decreased GDP binding to brown-adipose-tissue mitochondria of obese Zucker (fa/fa) rats in the very first days of life. Biochem. J. 221: 241-245, 1984.
3. Bazin, R., and M. Lavau. Development of hepatic and adipose tissue lipogenic enzymes and insulinemia during suckling and weaning on to a high-fat diet in Zucker rats. J. Lipid Res. 23: 839-849, 1982.
4. Bell, G. E., and J. S. Stern. Evaluation of body composition of young obese and lean Zucker rats. Growth 41: 63-80, 1977
5. Charon, C., V. Marie, F. Dupuy, and R. Bazin. Effect of chronic treatment with BRL-35135 on the onset of obesity in Zucker rat (fa/fa). Am. J. Physiol. 268 (Endocrinol. Metab. 31): E1039-E1045, 1995.
6. Don, R. H., P. T. Cox, B. J. Wainwright, K. Baker, and J. S. Mattick. "Touchdown" PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res. 19: 4008, 1991.
7. Girard, J. R. Control of fetal and neonatal glucose metabolism by pancreatic hormones. J. Clin. Endocrinol. Metab. 3: 817-836, 1989.
8. Girard, J. R., G. S. Cuendet, E. B. Marliss, A. Kervran, M. Rieutort, and R. Assan. Fuels, hormones, and liver metabolism at term and during the early postnatal period in the rat. J. Clin. Invest. 52: 3190-3200, 1973.
9. Isaad, T., C. Coupe, P. Ferre, and J. Girard. Insulin resistance during suckling period in rats. Am. J. Physiol. 253 (Endocrinol. Metab. 16): E142-E148, 1987.
10. Jauker, H., B. Meierfrankenfeld, M. Klingenspor, and I. Schmidt. Onset of obesity in fatty (fa/fa) Zucker rat × Brown Norway crosses (Abstract). Pfluegers Arch. 426, Suppl. 1, R100, 1994.
11. Johnson, J. A., and R. M. Fusaro. The quantitative enzymic determination of animal liver glycogen. Anal. Biochem. 15: 140-149, 1966.
12. Kaul, R., G. Heldmaier, and I. Schmidt. Defective thermoregulatory thermogenesis does not cause onset of obesity in Zucker rats. Am. J. Physiol. 259 (Endocrinol. Metab. 22): E11-E18, 1990.
13. Kaul, R., I. Schmidt, and H. J. Carlisle. Maturation of thermoregulation in Zucker rats. Int. J. Obesity 9: 401-409, 1985.
14. Kershaw, E. E., S. C. Chua, J. A. Williams, E. M. Murphy, and R. L. Leibel. Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus. Genomics 27: 149-154, 1995.
15. Körtner, G., O. Petrova, S. Vogt, and I. Schmidt. Sympathetically and nonsympathetically mediated onset of excess fat deposition in Zucker rats. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E947-E953, 1994.
16. Körtner, G., K. Schildhauer, O. Petrova, and I. Schmidt. Rapid changes in metabolic cold defense and GDP binding to brown adipose tissue mitochondria of rat pups. Am. J. Physiol. 264 (Regulatory Integrate Comp. Physiol. 33): R1017-R1023, 1993.
17. Llobera, M., A. Montes, and E. Herrera. Lipoprotein lipase activity in liver of the rat fetus. Biochem. Biophys. Res. Commun. 91: 272-277, 1979.
18. Markewicz, B., G. Kuhmichel, and I. Schmidt. Onset of excess fat deposition in Zucker rats with and without decreased thermogenesis. Am. J. Physiol. 265 (Endocrinol. Metab. 28): E478-E436, 1993.
19. Mayor, F., and J. M. Cuezva. Hormonal and metabolic changes in the perinatal period. Biol. Neonate 48: 185-196, 1985.
20. Moore, S. S., L. L. Sargeant, T. J. King, J. S. Mattick, M. Georges, and J. S. Hetzel. The conservation of dinucleotide microsatellites among mammalian genomes allows the use of heterologous PCR primer pairs in closely related species. Genomics 10: 654-660, 1991.
21. Penicaud, L., P. Ferré, F. Assimacopoulos-Jeannet, D. Perdereau, A. Leturque, B. Jeanrenaud, L. Picon, and J. Girard. Increased gene expression of lipogenic enzymes and glucose transporter in white adipose tissue of suckling and weaned obese Zucker rats. Biochem. J. 279: 303-308, 1991.
22. Péquignot-Planche, É., P. de Gasquet, A. Boulangé, and N. T. Tonnu. Lipoprotein lipase activity at onset of development of white adipose tissue in newborn rats. Biochem. J. 162: 461-463, 1977.
23. Ricquier, D., and P. Hemon. A study of phospholipids and triglycerides in several tissues of the rat during fetal and neonatal development. Biol. Neonate 28: 225-240, 1976.
24. Rohner-Jeanrenaud, F., and B. Jeanrenaud. Involvement of the cholinergic system to insulin and glucagon oversecretion of genetic preobesity. Endocrinology 116: 830-834, 1985.
25. Schmidt, I., R. Kaul, and H. J. Carlisle. Body temperature of huddling newborn Zucker rats. Pfluegers Arch. 401: 418-420, 1984.
26. Schmidt, I., R. Kaul, and G. Heldmaier. Thermoregulation and diurnal rhythms in 1-week-old rat pups. Can. J. Physiol. Pharmacol. 65: 1355-1364, 1987.
27. Taylor, P. M. Oxygen consumption in new-born rats. J. Physiol. Lond. 154: 153-168, 1960.
28. Tenenbaum, R., F. Y. Ochoa, M. L. Sassano, S. C. Chua, R. L. Leibel, and L. A. Campfield. Altered insulin secretion from the pancreas of pre-obese Zucker rat pups: evidence for an early and persistent genetic defect (Abstract). Int. J. Obesity 18, Suppl. 2: P258, 1994.
29. Truett, G. E, N. Bahary, J. M. Friedman, and R. L. Leibel. Rat obesity gene fatty (fa/fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db). Proc. Natl. Acad. Sci. USA 88: 7806-7809, 1991.
30. Truett, G. E., R. J. Tempelman, and J. A. Walker. Codominant effects of the fatty (fa) gene during early development of obesity. Am. J. Physiol. 268 (Endocrinol. Metab. 31): E15-E20, 1995.
31. Turkenkopf, I. J., P. R. Johnson, and M. R. C. Greenwood. Development of pancreatic and plasma insulin in prenatal and suckling Zucker rats. Am. J. Physiol. 242 (Endocrinol. Metab. 5): E220-E225, 1982.