메뉴 건너뛰기




Volumn 172, Issue 2, 2002, Pages 105-117

Treatment of chronic wounds: State of the art and future concepts

Author keywords

Gene transfer; Growth factor wound therapy; Skin equivalents; Wound therapy; Wounds, chronic

Indexed keywords

ADENOVIRUS VECTOR; ANTIBIOTIC AGENT; CHLORHEXIDINE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH FACTOR; HEXACHLOROPHENE; HYALURONIC ACID; HYDROGEN PEROXIDE; IODINE; NITRIC OXIDE SYNTHASE; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED WOUND HEALING FACTOR; QUATERNARY AMMONIUM DERIVATIVE; SILVER; UNCLASSIFIED DRUG; GROWTH PROMOTOR;

EID: 0036440651     PISSN: 14226405     EISSN: None     Source Type: Journal    
DOI: 10.1159/000065611     Document Type: Article
Times cited : (59)

References (89)
  • 2
    • 0026512863 scopus 로고
    • The surgical applications and implications of cultured human epidermis: A comprehensive review
    • Arons, J.A., D.J. Wainwright, R.E. Joran (1992) The surgical applications and implications of cultured human epidermis: A comprehensive review. Surgery 111: 4-11.
    • (1992) Surgery , vol.111 , pp. 4-11
    • Arons, J.A.1    Wainwright, D.J.2    Joran, R.E.3
  • 3
    • 0025033429 scopus 로고
    • Use of homologous platelet factors in achieving total healing of recalcitrant skin ulcers
    • Atri, S.C., J. Misra, D. Bishet, et al (1990) Use of homologous platelet factors in achieving total healing of recalcitrant skin ulcers. Surgery 108: 508-514.
    • (1990) Surgery , vol.108 , pp. 508-514
    • Atri, S.C.1    Misra, J.2    Bishet, D.3
  • 4
    • 0028799826 scopus 로고
    • Transplantation of transduced chondrocytes protects articular cartilage from IL-1 induced extracellular matrix degradation
    • Baragi, V.M., R.R. Renkiewicz, H. Jordan, J. Bonadio, J.W. Hartmann (1995) Transplantation of transduced chondrocytes protects articular cartilage from IL-1 induced extracellular matrix degradation. J Clin Invest 96: 2454-2460.
    • (1995) J Clin Invest , vol.96 , pp. 2454-2460
    • Baragi, V.M.1    Renkiewicz, R.R.2    Jordan, H.3    Bonadio, J.4    Hartmann, J.W.5
  • 5
    • 0019448705 scopus 로고
    • Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness
    • Bell, E., H.P. Ehrlich, D.J. Buttle, T. Nakatsuji (1981) Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness. Science 211: 1052-1054.
    • (1981) Science , vol.211 , pp. 1052-1054
    • Bell, E.1    Ehrlich, H.P.2    Buttle, D.J.3    Nakatsuji, T.4
  • 7
    • 0027219558 scopus 로고
    • Growth factors and wound healing: Biochemical properties of growth factors and their receptors
    • Bennett, N.T., G.S. Schultz (1993) Growth factors and wound healing: Biochemical properties of growth factors and their receptors. Am J Surg 165: 728-737.
    • (1993) Am J Surg , vol.165 , pp. 728-737
    • Bennett, N.T.1    Schultz, G.S.2
  • 8
    • 0033021062 scopus 로고    scopus 로고
    • Localized, direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration
    • Bonadio, J., E. Smily, P. Patil, S. Goldstein (1999) Localized, direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration. Nat Med 5: 753-759.
    • (1999) Nat Med , vol.5 , pp. 753-759
    • Bonadio, J.1    Smily, E.2    Patil, P.3    Goldstein, S.4
  • 9
    • 0029562891 scopus 로고
    • Comparative assessment of cultured skin substitutes and native skin autograft for treatment of full-thickness burns
    • Boyce, S.T., M.J. Goretsky, D.G. Greenhalgh, R.J. Kagan, M.T. Rieman, G.D. Warden (1995) Comparative assessment of cultured skin substitutes and native skin autograft for treatment of full-thickness burns. Ann Surg 222: 743-752.
    • (1995) Ann Surg , vol.222 , pp. 743-752
    • Boyce, S.T.1    Goretsky, M.J.2    Greenhalgh, D.G.3    Kagan, R.J.4    Rieman, M.T.5    Warden, G.D.6
  • 10
    • 0024328519 scopus 로고
    • Enhancement of wound healing by topical treatment with EGF
    • Brown, G.L., L.B. Nanney, J. Griffin, et al (1989) Enhancement of wound healing by topical treatment with EGF. N Engl J Med 321: 76-79.
    • (1989) N Engl J Med , vol.321 , pp. 76-79
    • Brown, G.L.1    Nanney, L.B.2    Griffin, J.3
  • 11
    • 0019449730 scopus 로고
    • Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury
    • Burke, A.M., I.V. Yannas, W.C. Quinby, C.C. Bondoc, W.K. Jung (1981) Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury. Ann Surg 194: 413-428.
    • (1981) Ann Surg , vol.194 , pp. 413-428
    • Burke, A.M.1    Yannas, I.V.2    Quinby, W.C.3    Bondoc, C.C.4    Jung, W.K.5
  • 12
    • 0027155874 scopus 로고
    • In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment
    • Cheng, L., P.R. Ziegelhoffer, N.S. Yang (1993) In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment. Proc Natl Acad Sci USA 90: 4455-4459.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4455-4459
    • Cheng, L.1    Ziegelhoffer, P.R.2    Yang, N.S.3
  • 14
    • 0022359409 scopus 로고
    • Cutaneous tissue repair: Basic biologic considerations
    • Clark, R.A.F. (1985) Cutaneous tissue repair: Basic biologic considerations. Am Acad Dermatol 13: 701-725.
    • (1985) Am Acad Dermatol , vol.13 , pp. 701-725
    • Clark, R.A.F.1
  • 15
    • 0032898829 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo controlled, dose-ranging study of Gm-CSF in patients with chronic venous leg ulcers
    • da Costa, R.M., F.M. Ribeiro Jesus, C. Aniceto, M. Mendes (1999) Randomized, double-blind, placebo controlled, dose-ranging study of Gm-CSF in patients with chronic venous leg ulcers. Wound Repair Regen 7: 17-25.
    • (1999) Wound Repair Regen , vol.7 , pp. 17-25
    • Da Costa, R.M.1    Ribeiro Jesus, F.M.2    Aniceto, C.3    Mendes, M.4
  • 16
    • 0023732333 scopus 로고
    • Comparison of the effects of moist and dry conditions on dermal repair
    • Dyson, M., S. Young, C. Pendle (1988) Comparison of the effects of moist and dry conditions on dermal repair. J Invest Dermatol 91: 434-439.
    • (1988) J Invest Dermatol , vol.91 , pp. 434-439
    • Dyson, M.1    Young, S.2    Pendle, C.3
  • 17
    • 0032469675 scopus 로고    scopus 로고
    • Dermagraft treatment of diabetic ulcers
    • Eaglstein, W.H. (1998) Dermagraft treatment of diabetic ulcers. J Dermatol 25: 803-804.
    • (1998) J Dermatol , vol.25 , pp. 803-804
    • Eaglstein, W.H.1
  • 18
    • 0032106879 scopus 로고    scopus 로고
    • Tissue engineering and the development of Apligraf a human skin equivalent
    • Eaglstein, W.H., V. Falanga (1998) Tissue engineering and the development of Apligraf a human skin equivalent. Adv Wound Care 11(4 suppl): 1-8.
    • (1998) Adv Wound Care , vol.11 , Issue.4 SUPPL. , pp. 1-8
    • Eaglstein, W.H.1    Falanga, V.2
  • 19
    • 0029559483 scopus 로고
    • Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice
    • Eming, S.A., J. Lee, R.G. Snow, R.G. Tompkins, M.L. Yarmush, J.R. Morgan (1995) Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice. J Invest Dermatol 105: 756-763.
    • (1995) J Invest Dermatol , vol.105 , pp. 756-763
    • Eming, S.A.1    Lee, J.2    Snow, R.G.3    Tompkins, R.G.4    Yarmush, M.L.5    Morgan, J.R.6
  • 20
    • 0032032617 scopus 로고    scopus 로고
    • Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft
    • Eming, S.A., D.A. Medalie, R.G. Tompkins, M.L. Yarmush, J.R. Morgan (1998) Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft. Hum Gene Ther 9: 529-539.
    • (1998) Hum Gene Ther , vol.9 , pp. 529-539
    • Eming, S.A.1    Medalie, D.A.2    Tompkins, R.G.3    Yarmush, M.L.4    Morgan, J.R.5
  • 21
    • 0030731716 scopus 로고    scopus 로고
    • Gene therapy for tissue repair: Approaches and prospects
    • Eming, S.A., J.R. Morgan, A. Berger (1997) Gene therapy for tissue repair: Approaches and prospects. Br J Plast Surg 50: 491-500.
    • (1997) Br J Plast Surg , vol.50 , pp. 491-500
    • Eming, S.A.1    Morgan, J.R.2    Berger, A.3
  • 22
    • 0030056484 scopus 로고    scopus 로고
    • Targeted expression of IGF-1 to human keratinocytes: Modification of the autocrine control of keratinocyte proliferation
    • Eming, S.A., R.G. Snow, M.L. Yarmush, J.R. Morgan (1996) Targeted expression of IGF-1 to human keratinocytes: Modification of the autocrine control of keratinocyte proliferation. J Invest Dermatol 106: 113-120.
    • (1996) J Invest Dermatol , vol.106 , pp. 113-120
    • Eming, S.A.1    Snow, R.G.2    Yarmush, M.L.3    Morgan, J.R.4
  • 25
    • 0027078190 scopus 로고
    • Growth factors and chronic wounds: The need to understand the microenvironment
    • Falanga, V. (1992) Growth factors and chronic wounds: The need to understand the microenvironment. J Dermatol 19: 667-672.
    • (1992) J Dermatol , vol.19 , pp. 667-672
    • Falanga, V.1
  • 26
    • 0027155669 scopus 로고
    • Chronic wounds: Pathophysiologic and experimental considerations
    • Falanga, V. (1993) Chronic wounds: Pathophysiologic and experimental considerations. J Invest Dermatol 100: 721-725.
    • (1993) J Invest Dermatol , vol.100 , pp. 721-725
    • Falanga, V.1
  • 27
    • 20644461035 scopus 로고    scopus 로고
    • Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent
    • Falange, V., D. Margolis, O. Alvarez, M. Auletta, F. Maggiacomo, M. Altman, et al (1998) Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Arch Dermatol 134: 293-300.
    • (1998) Arch Dermatol , vol.134 , pp. 293-300
    • Falange, V.1    Margolis, D.2    Alvarez, O.3    Auletta, M.4    Maggiacomo, F.5    Altman, M.6
  • 28
    • 0032879349 scopus 로고    scopus 로고
    • Immunization via hair follicles by topical application of naked DNA to normal skin
    • Fan, H., Q. Lin, G.R. Morrissey, P.A. Khavari (1999) Immunization via hair follicles by topical application of naked DNA to normal skin. Nat Biotechnol 17: 870-872.
    • (1999) Nat Biotechnol , vol.17 , pp. 870-872
    • Fan, H.1    Lin, Q.2    Morrissey, G.R.3    Khavari, P.A.4
  • 29
    • 0026430686 scopus 로고
    • Gene therapeutics
    • Felgner, P.L., G. Rhodes (1991) Gene therapeutics. Nature 349: 351-352.
    • (1991) Nature , vol.349 , pp. 351-352
    • Felgner, P.L.1    Rhodes, G.2
  • 30
    • 0024978864 scopus 로고
    • Cationic liposome-mediated transfection
    • Felgner, P.L., G.M. Ringold (1989) Cationic liposome-mediated transfection. Nature 337: 387-388.
    • (1989) Nature , vol.337 , pp. 387-388
    • Felgner, P.L.1    Ringold, G.M.2
  • 31
    • 0028631085 scopus 로고
    • Systemic delivery of secreted protein by grafts of epidermal keratinocytes: Prospects for keratinocyte gene therapy
    • Fenjves, E.S., J. Smith, S. Zaradic, L.B. Taichman (1994) Systemic delivery of secreted protein by grafts of epidermal keratinocytes: Prospects for keratinocyte gene therapy. Hum Gene Ther 5: 1241-1248.
    • (1994) Hum Gene Ther , vol.5 , pp. 1241-1248
    • Fenjves, E.S.1    Smith, J.2    Zaradic, S.3    Taichman, L.B.4
  • 32
    • 0026937479 scopus 로고
    • A brief history of gene therapy
    • Friedmann, T. (1992) A brief history of gene therapy. Nat Genet 2: 93-98.
    • (1992) Nat Genet , vol.2 , pp. 93-98
    • Friedmann, T.1
  • 33
    • 0030070640 scopus 로고    scopus 로고
    • Effects of bFGF on cartilage regeneration in chondrocyte-seeded sponge scaffold
    • Fujisate, T., T. Sajiki, O. Liu, Y. Ikada (1996) Effects of bFGF on cartilage regeneration in chondrocyte-seeded sponge scaffold. Biomaterials 17: 155-162.
    • (1996) Biomaterials , vol.17 , pp. 155-162
    • Fujisate, T.1    Sajiki, T.2    Liu, O.3    Ikada, Y.4
  • 34
    • 0029991342 scopus 로고    scopus 로고
    • Use of dermagraft, a cultured human dermis, to treat diabetic foot ulcers
    • Gentzkow, G.D., S.D. Iwasaki (1996) Use of dermagraft, a cultured human dermis, to treat diabetic foot ulcers. Diabetes Care 19: 350-354.
    • (1996) Diabetes Care , vol.19 , pp. 350-354
    • Gentzkow, G.D.1    Iwasaki, S.D.2
  • 35
    • 0027465539 scopus 로고
    • Towards gene therapy for haemophilia B using primary human keratinocytes
    • Gerrard, A.J., D.L. Hudson, G.G. Brownlee, F.M. Watt (1993) Towards gene therapy for haemophilia B using primary human keratinocytes. Nat Genet 3: 180-183.
    • (1993) Nat Genet , vol.3 , pp. 180-183
    • Gerrard, A.J.1    Hudson, D.L.2    Brownlee, G.G.3    Watt, F.M.4
  • 36
    • 0032796775 scopus 로고    scopus 로고
    • In vivo transduction of mouse epidermis with recombinant retroviral vectors: Implications for cutaneous gene therapy
    • Ghazizadeh, S., R. Harrington, L. Taichman (1999) In vivo transduction of mouse epidermis with recombinant retroviral vectors: Implications for cutaneous gene therapy. Gene Ther 6: 1267-1275.
    • (1999) Gene Ther , vol.6 , pp. 1267-1275
    • Ghazizadeh, S.1    Harrington, R.2    Taichman, L.3
  • 38
    • 0029053818 scopus 로고
    • Cytokine gene expression in epidermis with both biological effects following injection of naked DNA
    • Hengge, U.R., E.F. Chan, R.A. Foster, P.S. Walker, J.C. Vogel (1995) Cytokine gene expression in epidermis with both biological effects following injection of naked DNA. Nat Genet 10: 161-166.
    • (1995) Nat Genet , vol.10 , pp. 161-166
    • Hengge, U.R.1    Chan, E.F.2    Foster, R.A.3    Walker, P.S.4    Vogel, J.C.5
  • 40
    • 0011705459 scopus 로고
    • Phenotypic reversion of junctional epidermolysis bullosa keratinocytes by introduction of a therapeutic laminin 5 chain gene
    • Hoeffler, W.K., C.K. Wang, C. Matsui (1995) Phenotypic reversion of junctional epidermolysis bullosa keratinocytes by introduction of a therapeutic laminin 5 chain gene. J Invest Dermatol 104: 597.
    • (1995) J Invest Dermatol , vol.104 , pp. 597
    • Hoeffler, W.K.1    Wang, C.K.2    Matsui, C.3
  • 41
    • 21144460031 scopus 로고
    • A randomized, controlled multicenter, dose response trial of activated platelet supernatant, topical CT-102 in chronic, non-healing, diabetic wounds
    • Holloway, G.A., D.L. Steed, M.J. deMarco, et al (1993) A randomized, controlled multicenter, dose response trial of activated platelet supernatant, topical CT-102 in chronic, non-healing, diabetic wounds. Wounds 5: 198-201.
    • (1993) Wounds , vol.5 , pp. 198-201
    • Holloway, G.A.1    Steed, D.L.2    DeMarco, M.J.3
  • 42
    • 0031465397 scopus 로고    scopus 로고
    • Therapeutic gene delivery to the skin
    • Khavari, P.A. (1997) Therapeutic gene delivery to the skin. Mol Med Today 3: 533-538.
    • (1997) Mol Med Today , vol.3 , pp. 533-538
    • Khavari, P.A.1
  • 44
    • 0023244634 scopus 로고
    • High-velocity microprojectiles for delivering nucleic acids into living cells
    • Klein, T.M., E.D. Wolf, R. Wu, J.C. Sanford (1987) High-velocity microprojectiles for delivering nucleic acids into living cells. Nature 327: 70-73.
    • (1987) Nature , vol.327 , pp. 70-73
    • Klein, T.M.1    Wolf, E.D.2    Wu, R.3    Sanford, J.C.4
  • 46
    • 0022530730 scopus 로고
    • Classification and treatment of chronic non-healing wounds. Successful treatment with autologous platelet-derived wound healing factors (PDWHF)
    • Knighton, D.R., G.D. Phillips, V.D. Fliegel (1986) Classification and treatment of chronic non-healing wounds. Successful treatment with autologous platelet-derived wound healing factors (PDWHF). Ann Surg 204: 322-330.
    • (1986) Ann Surg , vol.204 , pp. 322-330
    • Knighton, D.R.1    Phillips, G.D.2    Fliegel, V.D.3
  • 49
    • 0028052937 scopus 로고
    • Growth factors in wound healing
    • Lawrene, T., R.F. Diegelman (1994) Growth factors in wound healing. Clin Dermatol 12: 157-169.
    • (1994) Clin Dermatol , vol.12 , pp. 157-169
    • Lawrene, T.1    Diegelman, R.F.2
  • 50
    • 0024602845 scopus 로고
    • Transient expression of a transfected gene in cultured epidermal keratinocytes: Implications for future studies
    • Lee, J.I., L.B. Taichman (1989) Transient expression of a transfected gene in cultured epidermal keratinocytes: Implications for future studies. J Invest Dermatol 92: 267-271.
    • (1989) J Invest Dermatol , vol.92 , pp. 267-271
    • Lee, J.I.1    Taichman, L.B.2
  • 51
    • 0029032807 scopus 로고
    • The feasibility of targeted selective gene therapy of the hair follicle
    • Li, L., R.M. Hoffman (1995) The feasibility of targeted selective gene therapy of the hair follicle. Nat Genet 1: 705-706.
    • (1995) Nat Genet , vol.1 , pp. 705-706
    • Li, L.1    Hoffman, R.M.2
  • 53
    • 0030099523 scopus 로고
    • A model for keratinocyte gene therapy: Preclinical and therapeutic considerations
    • Lu, B., G. Scott, L.A. Goldsmith (1995) A model for keratinocyte gene therapy: Preclinical and therapeutic considerations. Proc Assoc Am Phys 108: 165-172.
    • (1995) Proc Assoc Am Phys , vol.108 , pp. 165-172
    • Lu, B.1    Scott, G.2    Goldsmith, L.A.3
  • 55
    • 0030934532 scopus 로고    scopus 로고
    • Wound healing - Aiming for perfect skin regeneration
    • Martin, P. (1997) Wound healing - Aiming for perfect skin regeneration. Science 276: 75-81.
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 56
    • 0023273993 scopus 로고
    • Expression of an exogenous growth hormone gene by transplantable human epidermal cells
    • Morgan, J.R., Y. Barrandon, H. Green, R.C. Mulligan (1987) Expression of an exogenous growth hormone gene by transplantable human epidermal cells. Science 237: 1476-1479.
    • (1987) Science , vol.237 , pp. 1476-1479
    • Morgan, J.R.1    Barrandon, Y.2    Green, H.3    Mulligan, R.C.4
  • 57
    • 0027745761 scopus 로고
    • Advances in recombinant retroviruses for gene delivery
    • Morgan, J.R., R.G. Tompkins, M.L. Yarmush (1993) Advances in recombinant retroviruses for gene delivery. Adv Drug Deliv Rev 12: 143-158.
    • (1993) Adv Drug Deliv Rev , vol.12 , pp. 143-158
    • Morgan, J.R.1    Tompkins, R.G.2    Yarmush, M.L.3
  • 58
    • 0027231473 scopus 로고
    • Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts
    • Mouillier, P., D. Bohl, J.M. Heard, O. Danos (1993) Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts. Nat Genet 4: 154-159.
    • (1993) Nat Genet , vol.4 , pp. 154-159
    • Mouillier, P.1    Bohl, D.2    Heard, J.M.3    Danos, O.4
  • 59
    • 0028864850 scopus 로고
    • In vivo angiogenesis induced by recombinant adenovirus vectors coding either for secreted or nonsecreted forms of aFGF
    • Muhlhauser, J., R. Pili, M.J. Merrill, H. Maeda, A. Passaniti, R.G. Crystal, M.C. Capogrossi (1995) In vivo angiogenesis induced by recombinant adenovirus vectors coding either for secreted or nonsecreted forms of aFGF. Hum Gene Ther 6: 1457-1465.
    • (1995) Hum Gene Ther , vol.6 , pp. 1457-1465
    • Muhlhauser, J.1    Pili, R.2    Merrill, M.J.3    Maeda, H.4    Passaniti, A.5    Crystal, R.G.6    Capogrossi, M.C.7
  • 60
    • 0027595949 scopus 로고
    • The basic science of gene therapy
    • Mulligan, R.C. (1993) The basic science of gene therapy. Science 260: 926-932.
    • (1993) Science , vol.260 , pp. 926-932
    • Mulligan, R.C.1
  • 62
    • 0031665826 scopus 로고    scopus 로고
    • Early biological effect of in vivo gene transfer of PDGF-B into healing patellar ligament
    • Nakamura, N., K. Shino, T. Natsuume, S. Horibe, N. Matsumoto, Y. Kaneda, T. Ochi (1998) Early biological effect of in vivo gene transfer of PDGF-B into healing patellar ligament. Gene Ther 5: 1165-1170.
    • (1998) Gene Ther , vol.5 , pp. 1165-1170
    • Nakamura, N.1    Shino, K.2    Natsuume, T.3    Horibe, S.4    Matsumoto, N.5    Kaneda, Y.6    Ochi, T.7
  • 63
    • 70449205317 scopus 로고
    • The fine structure of the interrelationship of cells in the human epidermis
    • Odland, G. (1958) The fine structure of the interrelationship of cells in the human epidermis. J Biophys Biochem Cytol 4: 529-535.
    • (1958) J Biophys Biochem Cytol , vol.4 , pp. 529-535
    • Odland, G.1
  • 64
    • 0025976935 scopus 로고
    • Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes
    • Palmer, T.D., G.J. Rosman, W.R.A. Osborne, A.D. Miller (1991) Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. Proc Natl Acad Sci USA 88: 1330-1334.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1330-1334
    • Palmer, T.D.1    Rosman, G.J.2    Osborne, W.R.A.3    Miller, A.D.4
  • 67
    • 0026617969 scopus 로고
    • Clinical applications of cultured epithelium
    • Phillips, T.J., B Gilchrist (1992) Clinical applications of cultured epithelium. Epithelial Cell Biol 1: 39-46.
    • (1992) Epithelial Cell Biol , vol.1 , pp. 39-46
    • Phillips, T.J.1    Gilchrist, B.2
  • 68
    • 0016729431 scopus 로고
    • Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells
    • Rheinwald, J.G., H. Green (1975) Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells. Cell 6: 331-343.
    • (1975) Cell , vol.6 , pp. 331-343
    • Rheinwald, J.G.1    Green, H.2
  • 70
    • 0033805593 scopus 로고    scopus 로고
    • Surgical removal of ulcer and lipodermatosclerosis followed by split-skin grafting (shave therapy) yields good long-term results in nonhealing venous leg ulcers
    • Schmeller, W., Y Gaber (2000) Surgical removal of ulcer and lipodermatosclerosis followed by split-skin grafting (shave therapy) yields good long-term results in nonhealing venous leg ulcers. Acta Derm Venereol 80: 267-271.
    • (2000) Acta Derm Venereol , vol.80 , pp. 267-271
    • Schmeller, W.1    Gaber, Y.2
  • 72
    • 0033017213 scopus 로고    scopus 로고
    • DNA delivery from polymer matrices for tissue engineering
    • Shea, L.D., E. Smiley, J. Bonadio, D.J. Mooney (1999) DNA delivery from polymer matrices for tissue engineering. Nat Biotechnol 17: 551-554.
    • (1999) Nat Biotechnol , vol.17 , pp. 551-554
    • Shea, L.D.1    Smiley, E.2    Bonadio, J.3    Mooney, D.J.4
  • 73
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • Singer, A.J., R.A.F. Clark (1999) Cutaneous wound healing. Lancet 341: 738-746.
    • (1999) Lancet , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.F.2
  • 74
    • 0027219202 scopus 로고
    • Mutual induction of growth factor gene expression by epidermal-dermal cell interaction
    • Smola, H., G. Thiekotter, N.E. Fusenig (1993) Mutual induction of growth factor gene expression by epidermal-dermal cell interaction. J Cell Biol 122: 417-429.
    • (1993) J Cell Biol , vol.122 , pp. 417-429
    • Smola, H.1    Thiekotter, G.2    Fusenig, N.E.3
  • 75
    • 0031845096 scopus 로고    scopus 로고
    • Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture
    • Smola, H., H.J. Stark, G. Thiekotter, N. Mirancea, T. Krieg, N.E. Fusenig (1998) Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture. Exp Cell Res 239: 399-410.
    • (1998) Exp Cell Res , vol.239 , pp. 399-410
    • Smola, H.1    Stark, H.J.2    Thiekotter, G.3    Mirancea, N.4    Krieg, T.5    Fusenig, N.E.6
  • 76
    • 0028873980 scopus 로고
    • Clinical evaluation of rh PDGF for the treatment of lower extremity diabetic ulcers
    • Diabetic Ulcer Study Group
    • Steed, D.L. (1995) Clinical evaluation of rh PDGF for the treatment of lower extremity diabetic ulcers. Diabetic Ulcer Study Group. J Vasc Surg 21: 71-81.
    • (1995) J Vasc Surg , vol.21 , pp. 71-81
    • Steed, D.L.1
  • 79
    • 0032422895 scopus 로고    scopus 로고
    • Cultivation and transplantation of epidermal keratinocytes
    • Terskikh, V.V., A.V. Vasiliev (1999) Cultivation and transplantation of epidermal keratinocytes. Int Rev Cytol 188: 41-72.
    • (1999) Int Rev Cytol , vol.188 , pp. 41-72
    • Terskikh, V.V.1    Vasiliev, A.V.2
  • 80
    • 0032151147 scopus 로고    scopus 로고
    • Gene therapy to prevent restenosis: The Boston experience
    • Tio, R.A., J.M. Isner, K. Walsh (1998) Gene therapy to prevent restenosis: The Boston experience. Semin Interv Cardiol 3: 205-210.
    • (1998) Semin Interv Cardiol , vol.3 , pp. 205-210
    • Tio, R.A.1    Isner, J.M.2    Walsh, K.3
  • 82
    • 0011774422 scopus 로고    scopus 로고
    • Efficacy and safety of rh PDGF-BB (becaplermin) in patients with non-healing lower extremity diabetic ulcer: A phase III randomized, double blind study
    • Wiemann, T.S., J.M. Smiell, Y. Su (1998) Efficacy and safety of rh PDGF-BB (becaplermin) in patients with non-healing lower extremity diabetic ulcer: A phase III randomized, double blind study. Diabetes Care 21: 821-827.
    • (1998) Diabetes Care , vol.21 , pp. 821-827
    • Wiemann, T.S.1    Smiell, J.M.2    Su, Y.3
  • 84
    • 36949072834 scopus 로고
    • Formation of scab and the rate of epithelialization of superficial wounds in the skin of the young domestic pig
    • Winter, G.D. (1962) Formation of scab and the rate of epithelialization of superficial wounds in the skin of the young domestic pig. Nature 193: 293-294.
    • (1962) Nature , vol.193 , pp. 293-294
    • Winter, G.D.1
  • 87
    • 0025600919 scopus 로고
    • In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment
    • Yang, N.S., J. Burkholder, B. Roberts, B. Martinell, D. McCabe (1990) In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Proc Natl Acad Sci USA 87: 9568-9572.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9568-9572
    • Yang, N.S.1    Burkholder, J.2    Roberts, B.3    Martinell, B.4    McCabe, D.5
  • 88
    • 0001193566 scopus 로고    scopus 로고
    • Methods for particle-mediated gene transfer into skin
    • Robbinson, P.D. (ed). Totowa, Humana Press
    • Yang, N.S., D.E. McCabe, W.F. Swain (1997) Methods for particle-mediated gene transfer into skin; in Robbinson, P.D. (ed): Gene Therapy Protocols. Totowa, Humana Press, pp 281-296.
    • (1997) Gene Therapy Protocols , pp. 281-296
    • Yang, N.S.1    McCabe, D.E.2    Swain, W.F.3
  • 89
    • 0029075794 scopus 로고
    • Gene gun and other non-viral approaches for cancer gene therapy
    • Yang, N.S., W.H. Sun (1995) Gene gun and other non-viral approaches for cancer gene therapy. Nat Med 1: 481-483.
    • (1995) Nat Med , vol.1 , pp. 481-483
    • Yang, N.S.1    Sun, W.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.