Prolactin signaling and Stat5: Going their own separate ways?

Breast Cancer Research

Volumn 4, Issue 6, 2002, Pages 209-212

  Brisken, Cathrin ^a   Ayyanan, Ayyakkannu ^a   Doppler, Wolfgang ^b  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Cell adhesion; Mammary epithelium; Prolactin receptor; Stat5; Steroid hormones

Indexed keywords

PROLACTIN; PROLACTIN RECEPTOR; STAT5 PROTEIN;

BREAST DEVELOPMENT; BREAST DUCT; BREAST EPITHELIUM; CELL DIFFERENTIATION; CELL MUTANT; CYTOARCHITECTURE; EPITHELIUM CELL; FEMALE; HORMONAL REGULATION; MOUSE; NONHUMAN; PREGNANCY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; DNA-BINDING PROTEINS; ESTROGENS; JANUS KINASE 2; MAMMARY GLANDS, ANIMAL; MICE; MICE, KNOCKOUT; MILK PROTEINS; PHENOTYPE; PROGESTERONE; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, PROLACTIN; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

EID: 0036439680     PISSN: 14655411     EISSN: None     Source Type: Journal    
DOI: 10.1186/bcr543     Document Type: Review

References (27)

1. Nandi S: Endocrine control of mammary-gland development in the C3H/He Crgl mouse. J Natl Cancer Inst 1958, 21:1039-1063.
2. Lyons WR: Hormonal synergism in mammary growth. Proc R Soc Lond Ser B 1958, 149:303-325.
3. Horseman ND: Prolactin. In Endocrinology, vol 1, 4th edn. Edited by DeGroot LJ. WB Saunders; 2001:209-220.
4. Ginsburg E, Vonderhaar B: Prolactin synthesis and secretion by human breast cancer cells. Cancer Res 1995, 55:2591-2595.
5. Gill S, Peston D, Vonderhaar BK, Shousha S: Expression of prolactin receptors in normal, benign, and malignant breast tissue: an immunohistological study. J Clin Pathol 2001, 54: 956-960.
6. Goffin V, Kelly PN: The prolactin/growth hormone receptor family: structure/function relationships. J Mammary Gland Biol Neoplasia 1997, 2:7-17.
7. Rui H, Kirken RA, Farrar WL: Activation of receptor-associated tyrosine kinase JAK2 by prolactin. J Biol Chem 1994, 269: 5364-5368.
8. Groner B, Gouilleux F: Prolactin-mediated gene activation in mammary epithelial cells. Curr Opin Genet Dev 1995, 5:587-594.
9. Ihle JN, Stravapodis D, Parganas E, Thierfelder W, Feng J, Wang D, Teglund S: The roles of Jaks and Stats in cytokine signaling. Cancer J Sci Am 1998, 4(suppl 1):S84-S91.
10. Liu X, Robinson GW, Gouilleux F, Groner B, Hennighausen L: Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue. Proc Natl Acad Sci USA 1995, 92:8831-8835.
11. Ormandy CJ, Camus A, Barra J, Damotte D, Lucas B, Buteau H, Edery M, Brousse N, Babinet C, Binart N, Kelly PA: Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev 1997, 11:167-178.
12. Teglund S, McKay C, Schuetz E, van Deursen JM, Stravopodis D, Wang D, Brown M, Bodner S, Grosveld G, Ihle JN: Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 1998, 93:841-850.
13. Robinson GW, Hennighausen L, Johnson PF: Side-branching in the mammary gland: the progesterone-Wnt connection. Genes Dev 2000, 14:889-894.
14. DeOme KB, Faulkin LJ Jr, Bern HA, Blair PB: Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Res 1959, 19:511-520.
15. Brisken C, Kaur S, Chavarria T, Binart N, Sutherland R, Weinberg R, Kelly P, Ormandy C: Prolactin controls mammary gland development via direct and indirect mechanisms. Dev Biol 1999, 210:96-106.
16. Miyoshi K, Shillingford JM, Smith GH, Grimm SL, Wagner KU, Oka T, Rosen JM, Robinson GW, Hennighausen L: Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol 2001, 155:531-542.
17. Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey S, McMahon J, McMahon A, Weinberg R: Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev 2000, 14:650-654.
18. Kiesling M, Woldman I, Moriggl R, Hofmann J, Marine J-C, Ihle JN, Beug H, Decker T: Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Genes Dev 2000, 14:232-244.
19. Gallego MI, Binart N, Robinson GW, Okagaki R, Coschigano KT, Perry J, Kopchick JJ, Oka T, Kelly PA, Hennighausen L: Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effect. Dev Biol 2001, 229:163-175.
20. Jones FE, Welte T, Fu X-Y, Stern DF: ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation. J Cell Biol 1999, 147:77-88.
21. Cacalano NA, Sanden D, Johnston JA: Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras. Nat Cell Biol 2001, 3:460-465.
22. Tonko-Geymayer S, Goupille O, Tonko M, Soratroi C, Yoshimura A, Streuli C, Ziemiecki A, Kofler R, Doppler W: Regulation and function of the cytokine-inducible SH-2 domain proteins, CIS and SOCS3, in mammary epithelial cells. Mol Endocrinol 2002, 16:1680-1695.
23. Haslam SZ, Shyamala G: Effect of oestradiol on progesterone receptors in normal mammary glands and its relationship with lactation. Biochem J 1979, 182:127-131.
24. Mizoguchi Y, Kim JY, Enami J, Sakai S: The regulation of the prolactin receptor gene expression in the mammary gland of early pregnant mouse. Endocr J 1997, 44:53-58.
25. Gibori G, Richards JS, Keyes PL: Synergistic effects of prolactin and estradiol in the luteotropic process in the pregnant rat: regulation of estradiol receptor by prolactin. Biol Reprod 1979, 21:419-423.
26. Telleria CM, Zhong L, Deb S, Srivastava RK, Park KS, Sugino N, Park-Sarge OK, Gibori G: Differential expression of the estrogen receptors alpha and beta in the rat corpus luteum of pregnancy: regulation by prolactin and placental lactogens. Endocrinology 1998, 139:2432-2442.
27. Edery M, Imagawa W, Larson L, Nandi S: Regulation of estrogen and progesterone receptor levels in mouse mammary epithelial cells grown in serum-free collagen gel cultures. Endocrinology 1985, 116:105-112.