Activation of JAK2/STAT1-α-dependent signaling events during Mycobacterium tuberculosis-induced macrophage apoptosis

Cellular Immunology

Volumn 217, Issue 1-2, 2002, Pages 58-66

  Rojas, Mauricio ^a   Olivier, Martin ^b   García, Luis F ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Apoptosis; Cytokines; Infectious immunity bacteria; Monocytes macrophages; Nitric oxide

Indexed keywords

CASPASE; JANUS KINASE; NITRIC OXIDE; PROTEIN TYROSINE KINASE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; MACROPHAGE; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; CASPASES; CELL LINE; CELL NUCLEUS; ENZYME ACTIVATION; ENZYME INHIBITORS; INTERFERON-STIMULATED GENE FACTOR 3; JANUS KINASE 2; MACROPHAGES; MICE; MICE, INBRED C3H; MYCOBACTERIUM TUBERCULOSIS; NITRIC OXIDE; PHAGOCYTOSIS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0036435893     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-8749(02)00515-4     Document Type: Article

References (44)

1. G.E. Gilford, M.-L. Lohmann-Matthes, Gamma interferon priming of mouse and human macrophages for induction of tumor necrosis factor production by bacterial lipopolysaccharide, J. Natl. Cancer Inst. 78 (1987) 121.
2. P. Scuderi, K.E. Sterling, A.B. Raitano, T.M. Grogan, R.A. Rippe, Recombinant interferon-g stimulates the production of tumor necrosis factor in vitro, J. Interferon Res. 7 (1987) 155-163.
3. M.A. Collart, D. Belin, J.-D. Vassalli, S. de Kossodo, P. Vasalli, γ interferon enhances macrophage transcription of tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors, J. Exp. Med. 164 (1986) 2113-2120.
4. WAF1CIP1 mediated by STAT1, Science 272 (1996) 719-722.
5. Y.E. Chin, M. Kitagawa, K. Kuida, R.A. Flavell, X.Y. Fu, Activation of STAT signaling pathway can cause expression of caspase 1 and apoptosis, Mol. Cell. Biol. 17 (1997) 5328-5337.
6. J.J. Gao, D.C. Morrison, T.J. Parmely, S.W. Russell, W.J. Murphy, An interferon-γ-activated site (GAS) is necessary for full expression of the mouse inos gene in response to interferon-γ and lipopolysaccharide, J. Biol. Chem. 272 (1997) 1226-1230.
7. B.G. Darnay, B.B. Aggarwal, Early events in TNF signaling: A story of associations and dissociations, J. Leukoc. Biol. 61 (1997) 559-566.
8. C. Voelkel-Johnson, A.J. Entingh, W.S.M. Wold, L.R. Gooding, S.M. Laster, Activation of intracellular proteases is an early event in TNF-induced apoptosis, J. Immunol. 154 (1995) 1707-1716.
9. A.A. Beg, D. Baltimore, An essential role of NF-kB in preventing TNF-induced cell death, Science 274 (1996) 782-784.
10. M. Rojas, L.F. Barrera, G. Puzo, L.F. Garcia, Differential induction of apoptosis by virulent Mycobacterium tuberculosis in resistant and susceptible murine macrophages: Role of nitric oxide and mycobacterial products, J. Immunol. 159 (1997) 1352-1361.
11. M. Rojas, M. Olivier, P. Gros, L.F. Barrera, L.F. Garcia, TNF-α and IL-10 modulate the induction of apoptosis by virulent Mycobacterium tuberculosis in murine macrophages, J. Immunol. 162 (1999) 6122-6131.
12. 2+-dependent cell signaling, J. Infect. Dis. 182 (2000) 240-251.
13. M. Gilleron, N. Himoudi, O. Adam, P. Constant, A. Venisse, M. Riviere, G. Puzo, Mycobacterium smegmatis phosphoinositols-glyceroarabinomannans. Structure and localization of alkali-stable phosphoinositides, J. Biol. Chem. 272 (1997) 117-124.
14. G.P. Youmans, Tuberculosis, W.B. Saunders, Philadelphia, 1979.
15. s macrophages correlates with nitric oxide production, J. Infect. Dis. 176 (1997) 1552-1558.
16. D. Radzioch, T. Hudson, M. Boule, L. Barrera, J.W. Urbance, L. Varesio, E. Skamene, Genetic resistance/susceptibility to mycobacteria: Phenotypic expression in bone marrow-derived macrophage lines, J. Leukoc. Biol. 50 (1991) 263.
17. G. Forget, K.A. Siminovitch, S. Brochu, S. Rivest, D. Radzioch, M. Olivier, Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis, Eur. J. Immunol. 31 (2001) 3185-3196.
18. F. Rendu, A. Eldor, F. Grelac, C. Bachelot, A. Gazit, C. Gilon, S. Levy-Toledano, A. Levitzki, Inhibition of platelet activation by tyrosine kinase inhibitors, Biochem. Pharmacol. 44 (1992) 881-888.
19. J. De Vos, M. Jourdan, K. Tarte, C. Jasmin, B. Klein, JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells, Br. J. Haematol. 109 (2000) 823-828.
20. G.A.W. Rook, J. Steele, L. Fraher, S. Barker, R. Karmali, J. O'Riordan, Vitamin D3, γ interferon, and control proliferation of Mycobacterium tuberculosis by human monocytes, Immunology 57 (1986) 159-163.
21. M. Olivier, B.-J. Romero-Gallo, C. Matte, J. Blanchette, B. Posner, M.J. Tremblay, R. Faure, Modulation of interferon-τ-induced macrophage activation by phophotyrosine phosphatases inhibition: Effects on murine leishmaniasis progression, J. Biol. Chem. 273 (1998) 13944-13949.
22. R. Bernier, B. Barbeau, M.J. Trembay, M. Olivier, The lipophosphoglycan of Leishmania donavani up-regulates HIV-1 transcription in T cells through the nuclear factor-kB elements, J. Immunol. 160 (1998) 2881-2888.
23. A.E. Horvai, L. Xu, E. Korzus, G. Brard, D. Kalafus, T.M. Mullen, D.W. Rose, M.G. Rosenfeld, C.K. Glass, Nuclear integration of JAK/SATAT and Ras/AP-1 signaling by CBP and p300, Proc. Natl. Acad. Sci. USA 94 (1997) 1074-1079.
24. R. Kamijo, H. Harada, T. Matsuyama, M. Bosland, J. Gerecitano, D. Shapiro, J. Le, S.I. Koh, T. Kimura, S.J. Green, T.W. Mak, T. Taniguchi, J. Vilcek, Requirement for transcription factor IRF-1 in NO synthase induction in macrophages, Science 263 (1994) 1612-1615.
25. K.L. Knutson, Z. Hmama, P. Herrera-Velit, R. Rochford, N.E. Reiner, Lipoarabinomannan of Mycobacterium tuberculosis promotes protein tyrosine dephosphorylation and inhibition of mitogen-activated protein kinase in human mononuclear phagocytes: Role of the srchomology 2 contain in tyrosine phosphatase 1, J. Biol. Chem. 273 (1998) 645-652.
26. T. Bittorf, J. Seiler, Z. Zhang, R. Jaster, J. Brock, SHP1 protein tyrosine phosphatase negatively modulates erythroid differentiation and suppression of apoptosis in J2E erythroleukemic cells, Biol. Chem. 380 (1999) 1201-1209.
27. J. Blanchette, N. Racette, R. Faure, K.A. Siminovitch, M. Olivier, Leishmania-induced increases in activation of macrophage SHP-1 tyrosine phosphatase are associated with impaired IFN-γ-triggered JAK2 activation, Eur. J. Immunol. 29 (1999) 3737-3744.
28. L.M. Chen, K. Kaniga, J.E. Galan, Salmonella spp. are cytotoxic for cultured macrophages, Mol. Microbiol. 21 (1996) 1101-1115.
29. Z. Hmama, R. Gabathuler, W. Jefferies, G.D. Jong, N.E. Reiner, Attenuation of HLA-DR expression by mononuclear phagocytes infected with Mycobacterium tuberculosis is related to intracellular sequestration of immature class II heterodimers, J. Immunol. 161 (1998) 4882-4893.
30. A.B. Abdel-Mageed, K.C. Agrawal, Activation of nuclear factor κB: Potential role in metallothionein-mediated mitogenic response, Cancer Res. 58 (1998) 2335-2338.
31. T. Fujita, L.F. Reis, N. Watanabe, Y. Kimura, T. Taniguchi, J. Vilcek, Induction of the transcription factor IRF-1 and Interferon-B mRNAs by cytokines and activators of second-messenger pathways, Proc. Natl. Acad. Sci. USA 86 (1989) 9936-9940.
32. T. Kataoka, R.C. Budd, N. Holler, M. Thome, F. Martinon, M. Irmler, K. Burns, M. Hahne, N. Kennedy, M. Kovacsovics, J. Tschopp, The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways, Curr. Biol. 10 (2000) 640-648.
33. A.S. Baldwin Jr., The NF-kB and IkB proteins: New discoveries and insights, Annu. Rev. Immunol. 14 (1996) 649-681.
34. C. Chen, L.C. Edelstein, C. Gelinas, The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L), Mol. Cell Biol. 20 (2000) 2687-2695.
35. H.H. Lee, H. Dadgostar, Q. Cheng, J. Shu, G. Cheng, NF-κB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes, Proc. Natl. Acad. Sci. USA 96 (1999) 9136-9141.
36. L.S. Schlesinger, T.M. Kaufman, S. Iyer, S.R. Hull, L.K. Marchiando, Differences in mannose receptor-mediated uptake of lipoarabinomannan from virulent and attenuated strains of Mycobacterium tuberculosis by human macrophages, J. Immunol. 157 (1996) 4568-4575.
37. T.K. Means, E. Lien, A. Yoshimura, S. Wang, D.T. Golenbock, M.J. Fenton, The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for toll-like receptors, J. Immunol. 163 (1999) 6748-6755.
38. T.K. Means, S. Wang, E. Lien, A. Yoshimura, D.T. Golenbock, M.J. Fenton, Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis, J. Immunol. 163 (1999) 3920-3927.
39. D.M. Underhill, A. Ozinsky, Toll-like receptors: Key mediators of microbe detection, Curr. Opin. Immunol. 14 (2002) 103-110.
40. A. Ciaramella, A. Martino, R. Cicconi, V. Colizzi, M. Fraziano, Mycobacterial 19-kDa lipoprotein mediates Mycobacterium tuberculosis-induced apoptosis in monocytes/macrophages at early stages of infection, Cell. Death Differ. 7 (2000) 1270-1272.
41. M.J. Fenton, M.W. Vermeulen, Immunopathology of tuberculosis: Roles of macrophages and monocytes, Infect. Immun. 64 (1996) 683-690.
42. M. Belosevic, C.E. Davis, M.S. Meltzer, C.A. Nacy, Regulation of activated macrophage antimicrobial activities. Identification of lymphokines that cooperate with IFN-g for induction of resistance to infection, J. Immunol. 141 (1988) 890-896.
43. J. Flynn, J. Chan, K.J. Triebold, D.K. Dalton, T.A. Stewart, B.R. Bloom, An essential role for interferon τ in resistance to Mycobacterium tuberculosis infection, J. Exp. Med. 178 (1993) 2249-2254.
44. M.J. Newport, A mutation in the interferon-g receptor gene and susceptibility to mycobacterial infection, N. Engl. J. Med. 335 (1996) 1941-1949.