Adeno-associated viral gene transfer of dominant negative RhoA enhances erectile function in rats

Biochemical and Biophysical Research Communications

Volumn 298, Issue 3, 2002, Pages 427-432

  Chitaley, Kanchan ^a,d   Bivalacqua, Trinity J ^b   Champion, Hunter C ^c   Usta, Mustafa F ^b   Hellstrom, Wayne J G ^b   Mills, Thomas M ^a   Clinton Webb, R ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Division of Cardiology   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cavernosal; Erectile dysfunction; Erection; Gene therapy; Rho kinase; Vasoconstriction

Indexed keywords

BETA GALACTOSIDASE; MUTANT PROTEIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; ENZYME ACTIVATION; GENE TRANSFER; HYPOTHESIS; IN VIVO STUDY; MALE; MEAN ARTERIAL PRESSURE; NERVE STIMULATION; NONHUMAN; PENILE BLOOD VESSEL; PENIS ERECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VIRUS GENE;

ANIMALS; DEPENDOVIRUS; GENE TRANSFER TECHNIQUES; GENES, DOMINANT; MALE; PENILE ERECTION; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RHOA GTP-BINDING PROTEIN;

EID: 0036430608     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02458-0     Document Type: Article

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