Effect of rho-kinase inhibition on vasoconstriction in the penile circulation

Journal of Applied Physiology

Volumn 91, Issue 3, 2001, Pages 1269-1273

  Mills, Thomas M ^a   Chitaley, Kanchan ^a   Wingard, Christopher J ^a   Lewis, Ronald W ^a   Webb, R Clinton ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Endothelin 1; Methoxamine; Penile erection; Penis; Vasodilation

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CYCLIC GMP; ENDOTHELIN 1; METHOXAMINE; NITRIC OXIDE; RHO KINASE;

ANIMAL EXPERIMENT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CIRCULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PENIS; PENIS ERECTION; PRIORITY JOURNAL; VASOCONSTRICTION; VASODILATATION;

EID: 0034863248     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2001.91.3.1269     Document Type: Article

References (26)

1. Neurotransmission and the contraction and relaxation of penile erectile tissues
2. Physiology of penile erection
3. Possible role of bradykinin and angiotensin II in the regulation of penile erection and detumescence
4. The role of nitric oxide in the physiology of erection
5. RhoA/Rho-kinase: A novel player in the regulation of penile erection
6. Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway
7. Receptor-specific influence of endothelin-1 in the erectile response of the rat
8. Rho-associated kinase of chicken gizzard smooth muscle
9. The peripheral pharmacology of erection
10. Tissue angiotensin II as a modulator of erectile function. I. Angiotensin peptide content, secretion and effects in the corpus cavernosum
11. Protein measurement with the Folin phenol reagent
12. Pre-penile arteries are dominant in the regulation of penile vascular resistance in the rat
13. Endothelin-1-induced vasoconstriction is inhibited during erection in rats
14. Effects of castration and androgen replacement on the hemodynamics of penile erection in the rat
15. Androgen maintenance of erectile function in the rat penis
16. Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells
17. Monkey corpus cavernosum relaxation mediated by NO and other relaxing factor derived from nerves
18. Androgens modulate the alpha-adrenergic responsiveness of vascular smooth muscle in the corpus cavernosum
19. Androgenic regulation of NO availability in rat penile erection
20. 2+ sensitization of contraction in vascular smooth muscle
21. Vascular biology of endothelin
22. Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
23. Role of alpha adrenergic receptors in erectile function
24. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
25. Erection and NO override the vasoconstrictor effect of alpha adrenergic stimulation in the rat penile vasculature