Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4

Kidney International

Volumn 62, Issue 3, 2002, Pages 790-798

  Watanabe, Hidetsuna ^a,b   Xu, Jing ^a,b   Bengra, Chikh ^a,b   Jose, Pedro A ^a,b   Felder, Robin A ^a,b  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

GRK4; Hypertension; Renal proximal tubules; Sodium transport; Water and electron transport

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 1 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; ENZYME INHIBITOR; FENOLDOPAM; FORSKOLIN; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 4; HEPARIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; KIDNEY CELL; KIDNEY PROXIMAL TUBULE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; SEQUENCE HOMOLOGY; TREATMENT OUTCOME;

EID: 0036424228     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00525.x     Document Type: Article

References (54)

1. Jose PA, Eisner GM, Felder RA: The renal dopamine receptors in health and hypertension. Pharmacol Ther 80:149-182, 1998
2. Hussain T, Lokhandwala MF: Renal dopamine receptor function in hypertension. Hypertension 32:187-197, 1998
3. Aperia A: Intrarenal dopamine: A key signal in the interactive regulation of sodium metabolism. Annu Rev Physiol 62:621-647, 2000
4. + exchanger interactions in the kidney in hypertension. Hypertension 36:395-399, 2000
5. Kinoshita S, Sidhu A, Felder RA: Defective dopamine-1 receptor adenylate cyclase coupling in the proximal convoluted tubule from the spontaneously hypertensive rat. J Clin Invest 84:1849-1856, 1989
6. Debska-Slizien A, Ho P, Drangova R, Baines AD: Endogenous dopamine regulates phosphate reabsorption but not NaK-ATPase in spontaneously hypertensive rat kidneys. J Am Soc Nephrol 5: 1125-1132, 1994
7. q/11 proteins in spontaneously hypertensive rats. Am J Physiol 272:F339-F346, 1997
8. Sanada H, Jose PA, Hazen-Martin D, et al: Dopamine-1 receptor defect in renal proximal tubular cells in essential hypertension. Hypertension 33:1036-1042, 1999
9. Barton AC, Sibley DR: Agonist-induced desensitization of D1-dopamine receptors linked to adenylyl cyclase activity in cultured NS20Y neuroblastoma cells. Mol Pharmacol 38:531-541, 1990
10. Ng GY, Trogadis J, Stevens J, et al: Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and separated from D1 receptor internalization. Proc Natl Acad Sci USA 92:10157-10161, 1995
11. Tiberi M, Nash SR, Bertrand L, et al: Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases. J Biol Chem 271:3771-3778, 1996
12. 1 dopamine receptors with mutations of protein kinase phosphorylation sites: Attenuation of the rate of agonist-induced desensitization. Mol Pharmacol 56:675-683, 1999
13. Vickery RG, Von Zastrow M: Distinct dynamin-dependent and-independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes. J Cell Biol 144: 31-43, 1999
14. 1 dopamine receptor function: Evidence for a novel pathway for receptor dephosphorylation. Mol Pharmacol 59:310-321, 2001
15. Ferguson SS: Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling. Pharmacol Rev 53:1-24, 2001
16. Penn RB, Pronin AN, Benovic JL: Regulation of G protein-coupled receptor kinases. Trends Cardiovasc Med 10:81-89, 2000
17. Sallese M, Mariggio S, Collodel G, et al: G protein-coupled receptor kinase GRK4. Molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells. J Biol Chem 272:10188-10195, 1997
18. Premont RT, Macrae AD, Stoffel RH, et al: Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants. J Biol Chem 271:6403-6410, 1997
19. 2-adrenergic receptor and β-arrestin. Science 294:1307-1313, 2001
20. 2-adrenergic receptor facilitate sequestration. Biochemistry 35: 4155-4160, 1996
21. Virlon B, Firsov D, Cheval L, et al: Rat G protein-coupled receptor kinase GRK4: Identification, functional expression, and differential tissue distribution of two splice variants. Endocrinology 139:2784-2795, 1998
22. Iacovelli L, Sallese M, Mariggio S, De Blasi A: Regulation of G-protein-coupled receptor kinase subtypes by calcium sensor proteins. FASEB J 13:1-8, 1999
23. Dale LB, Bhattacharya M, Anborgh PH, et al: G protein-coupled receptor kinase-mediated desensitization of metabotropic glutamate receptor 1A protects against cell death. J Biol Chem 275: 38213-38220, 2000
24. Tsuga H, Okuno E, Kameyama K, Haga T: Sequestration of human muscarinic acetylcholine receptor hml-hm5 subtypes: Effect of G protein-coupled receptor kinases GRK2, GRK4, GRK5 and GRK6. J Pharmacol Exp Ther 284:1218-1226, 1998
25. 2A receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells. Mol Pharmacol 60:1020-1030, 2001
26. Eason MG, Kurose H, Holt BD, et al: Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs. J Biol Chem 267: 15795-15801, 1992
27. Bates MD, Caron MG, Raymond JR: Desensitization of DA1 dopamine receptors coupled to adenylyl cyclase in opossum kidney cells. Am J Physiol 260:F937-F945, 1991
28. Bates MD, Olsen CL, Becker BN, et al: Elevation of cAMP is required for down-regulation, but not agonist-induced desensitization, of endogenous dopamine D1 receptors in opossum kidney cells. Studies in cells that stably express a rat cAMP phosphodiesterase (rPDE3) cDNA. J Biol Chem 268:14757-14763, 1993
29. Loudon RP, Benovic JL: Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6. J Biol Chem 269:22691-22697, 1994
30. Kunapuli P, Onorato JJ, Hosey MM, Benovic JL: Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5. J Biol Chem 269:1099-1105, 1994
31. Pitcher JA, Tesmer JJ, Freeman JL, et al: Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem 274:34531-34534, 1999
32. Felder RA, Sanada H, Xu J, et al: G protein-coupled receptor kinase 4 gene variants in human essential hypertension. Proc Natl Acad Sci USA 99:3872-3877, 2002
33. 1 dopamine receptor in mutant Chinese hamster ovary cells deficient in cyclic AMP-dependent protein kinase activity. J Pharmacol Exp Ther 293:426-434, 2000
34. 1 dopamine receptor: Evidence for involvement of both cyclic AMP-dependent and receptor-specific protein kinases. Mol Cell Neurosci 2:464-472, 1991
35. Lewis MM, Watts VJ, Lawler CP, et al: Homologous desensitiza-tion of the DiA dopamine receptor: Efficacy in causing desensitization dissociates from both receptor occupancy and functional potency. J Pharmacol Exp Ther 286:345-353, 1998
36. Ofori S, Bugnon O, Schorderet M: Agonist-induced desensitization of dopamine D-1 receptors in bovine retina and rat striatum. J Pharmacol Exp Ther 266:350-357, 1990
37. Balmforth AJ, Warburton P, Ball SG: Homologous desensitization of the D1 dopamine receptor. J Neurochem 55:2111-2116, 1990
38. Ng GY, Mouillac B, George SR, et al: Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. Eur J Pharmacol 267:7-19, 1994
39. Sidhu A, Olde B, Humblot N, et al: Regulation of human D1 dopamine receptor function and gene expression in SK-N-MC neuroblastoma cells. Neuroscience 91:537-547, 1999
40. Lezcano N, Mrzljak L, Eubanks S, et al: Dual signaling regulated by calcyon, a D1 dopamine receptor interacting protein. Science 287:1660-1664, 2000
41. Pitcher JA, Freedman NJ, Lefkowitz RJ: G protein-coupled receptor kinases. Annu Rev Biochem 67:653-692, 1998
42. Brismar H, Asghar M, Carey RM, et al: Dopamine-induced recruitment of dopamine D1 receptors to the plasma membrane. Proc Natl Acad Sci USA 95:5573-5578, 1998
43. Schlegel A, Lisanti MP: Caveolae and their coat proteins, the caveolins: From electron microscopic novelty to biological launching pad. J Cell Physiol 186:329-337, 2001
44. Ostrom RS, POST SR, Insel PA: Stoichiometry and compartmentation in G protein-coupled receptor signaling: Implications for therapeutic interventions involving Gs. J Pharmacol Exp Ther 294:407412, 2000
45. Anderson RG: The caveolae membrane. Annu Rev Biochem 68: 199-225, 1998
46. Carman CV, Lisanti MP, Benovic JL: Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem 274:8858-8864, 1999
47. Fra AM, Williamson E, Simons K, Parton RG: De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin. Proc Natl Acad Sci USA 92:8655-8659, 1995
48. Scheiffele P, Verkade P, Fra AM, et al: Caveolin-1 and-2 in the exocytic pathway of MDCK cells. J Cell Biol 140:795-806, 2000
49. Verkade P, Harder T, Lafont F, Simons K: Induction of caveolae in the apical plasma membrane of Madin-Darby canine kidney cells. J Cell Biol 148:727-739, 2000
50. Vogel U, Sandvig K, Van Deurs B: Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells. J Cell Sci 111:825-832, 1998
51. 1 adenosine receptor and adenosine deaminase in an epithelial cell line. Mol Pharmacol 59:1314-1323, 2001
52. Breton S, Lisanti MP, Tyszkowski R, et al: Basolateral distribution of caveolin-1 in the kidney. Absence from H+-ATPase-coated endocytic vesicles in intercalated cells. J Histochem Cytochem 46: 205-214, 1998
53. Couet J, Sargiacomo M, Lisanti MP: Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities. J Biol Chem 272:30429-30438, 1997
54. Scherer PE, Lewis RY, Volonte et al: Cell-type and tissue-specific expression of caveolin-2. Caveolins i and 2 co-localize and form a stable hetero-oligomeric complex in vivo. J Biol Chem 272:2933729346, 1997