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Volumn 46, Issue 1, 2002, Pages 75-84

Protective effect of omeprazole against acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats

Author keywords

Compound 48 80; Gastric mucosal lesion (rat); Lipid peroxidation; Neutrophil infiltration; Omeprazole

Indexed keywords

ACID; COMPOUND 48-80; HEXOSAMINE; LIPID; LIPID PEROXIDE; MUCIN; MYELOPEROXIDASE; OMEPRAZOLE; THIOL DERIVATIVE; XANTHINE OXIDASE;

EID: 0036421210     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-6618(02)00034-8     Document Type: Article
Times cited : (30)

References (59)
  • 2
    • 0020654376 scopus 로고
    • Effect of omeprazole-a gastric proton pump inhibitor-on pentagastrin stimulated acid secretion in man
    • Lind T, Cederberg C, Ekenved G, Haglund U, Olbe L. Effect of omeprazole-a gastric proton pump inhibitor-on pentagastrin stimulated acid secretion in man. Gut 1983; 24: 270-6.
    • (1983) Gut , vol.24 , pp. 270-276
    • Lind, T.1    Cederberg, C.2    Ekenved, G.3    Haglund, U.4    Olbe, L.5
  • 4
    • 0021338996 scopus 로고
    • Effects of a proton pump inhibitor, omeprazole, on gastric acid secretion and gastric and duodenal ulcers or erosions in rats
    • Yamamoto O, Okada Y, Okabe S. Effects of a proton pump inhibitor, omeprazole, on gastric acid secretion and gastric and duodenal ulcers or erosions in rats. Dig Dis Sci 1984; 29: 394-401.
    • (1984) Dig Dis Sci , vol.29 , pp. 394-401
    • Yamamoto, O.1    Okada, Y.2    Okabe, S.3
  • 8
    • 0025375173 scopus 로고
    • Intravenous therapy with high doses of ranitidine and omeprazole in critically ill patients with bleeding peptic ulcerations on the upper intestinal track: An open randomized controlled trial
    • Brunner G, Chang J. Intravenous therapy with high doses of ranitidine and omeprazole in critically ill patients with bleeding peptic ulcerations on the upper intestinal track: An open randomized controlled trial. Digestion 1990; 45: 217-25.
    • (1990) Digestion , vol.45 , pp. 217-225
    • Brunner, G.1    Chang, J.2
  • 10
    • 0020584458 scopus 로고
    • Omeprazole provides protection against experimentally induced gastric mucosal lesions
    • Mattsson H, Andersson K, Larsson H. Omeprazole provides protection against experimentally induced gastric mucosal lesions. Eur J Pharmacol 1983; 91: 111-4.
    • (1983) Eur J Pharmacol , vol.91 , pp. 111-114
    • Mattsson, H.1    Andersson, K.2    Larsson, H.3
  • 11
    • 0020520971 scopus 로고
    • Protective action of omeprazole a benzimidazole derivative, on gastric mucosal damage by aspirin and ethanol in rats
    • Konturek SJ, Brzozowski T, Radecki T. Protective action of omepra-zole a benzimidazole derivative, on gastric mucosal damage by aspirin and ethanol in rats. Digestion 1983; 27: 159-64.
    • (1983) Digestion , vol.27 , pp. 159-164
    • Konturek, S.J.1    Brzozowski, T.2    Radecki, T.3
  • 12
    • 0024208218 scopus 로고
    • Effect of omeprazole on rat gastric mucus glycoproteins with acetylsalicylic acid-induced gastric damage
    • Ohara S, Murayama N, Kuwata H, Ishihara K, Hotta K. Effect of omeprazole on rat gastric mucus glycoproteins with acetylsalicylic acid-induced gastric damage. Arch Int Pharmacodyn 1988; 296: 192-201.
    • (1988) Arch Int Pharmacodyn , vol.296 , pp. 192-201
    • Ohara, S.1    Murayama, N.2    Kuwata, H.3    Ishihara, K.4    Hotta, K.5
  • 13
    • 0027971478 scopus 로고
    • Protective action of omeprazole against gastric mucosal injury induced by hemorrhagic shock in rats
    • Blandizzi C, Gheradi G, Natale G, Marveggio C, Del Tacca M. Protective action of omeprazole against gastric mucosal injury induced by hemorrhagic shock in rats. Dig Dis Sci 1994; 39: 2109-17.
    • (1994) Dig Dis Sci , vol.39 , pp. 2109-2117
    • Blandizzi, C.1    Gheradi, G.2    Natale, G.3    Marveggio, C.4    Del Tacca, M.5
  • 14
    • 0029050418 scopus 로고
    • Mechanisms of protection by omeprazole against experimental gastric mucosal damage in rats
    • Blandizzi C, Gheradi G, Marveggio G, Natale G, Carignari D, Del Tacca M. Mechanisms of protection by omeprazole against experimental gastric mucosal damage in rats. Digestion 1995; 56: 220-9.
    • (1995) Digestion , vol.56 , pp. 220-229
    • Blandizzi, C.1    Gheradi, G.2    Marveggio, G.3    Natale, G.4    Carignari, D.5    Del Tacca, M.6
  • 17
    • 0033016485 scopus 로고    scopus 로고
    • Role of endothelin-1 and constitutive nitric oxide synthase in gastric mucosal resistance to indomethacin injury: Effect of antiulcer agents
    • Slomiany BL, Piotrowaki J, Slomiany A. Role of endothelin-1 and constitutive nitric oxide synthase in gastric mucosal resistance to indomethacin injury: Effect of antiulcer agents. Scand J Gastroenterol 1999; 34: 459-64.
    • (1999) Scand J Gastroenterol , vol.34 , pp. 459-464
    • Slomiany, B.L.1    Piotrowaki, J.2    Slomiany, A.3
  • 18
    • 0021874125 scopus 로고
    • Role of gastric acid and bile acids in the pathogenesis of compound 48/80-induced gastric lesions in rats
    • Ohtsuki H, Takeuchi K, Okabe S. Role of gastric acid and bile acids in the pathogenesis of compound 48/80-induced gastric lesions in rats. Jpn J Pharmacol 1985; 38: 253-7.
    • (1985) Jpn J Pharmacol , vol.38 , pp. 253-257
    • Ohtsuki, H.1    Takeuchi, K.2    Okabe, S.3
  • 19
    • 0026552216 scopus 로고
    • Effects of omeprazole on neutrophil chemotaxis, superoxide production, degradation, and translocation of cytochrome b-245
    • Wandall JH. Effects of omeprazole on neutrophil chemotaxis, superoxide production, degradation, and translocation of cytochrome b-245. Gut 1992; 33: 617-21.
    • (1992) Gut , vol.33 , pp. 617-621
    • Wandall, J.H.1
  • 20
    • 0033051177 scopus 로고    scopus 로고
    • Omeprazole attenuates neutrophil-endothelial cell adhesive interaction induced by extracts of Helicobacter pylori
    • Suzuki M, Mori M, Fukumura D, Suzuki H, Miura S, Ishii H. Omeprazole attenuates neutrophil-endothelial cell adhesive interaction induced by extracts of Helicobacter pylori. J Gastroenterol Hepatol 1999; 14: 27-31.
    • (1999) J Gastroenterol Hepatol , vol.14 , pp. 27-31
    • Suzuki, M.1    Mori, M.2    Fukumura, D.3    Suzuki, H.4    Miura, S.5    Ishii, H.6
  • 21
    • 0033960374 scopus 로고    scopus 로고
    • Inhibitory effect of omeprazole on transmigration of leukocytes through endothelial cell monolayer and leukocyte adhesion
    • Holbauer R, Loset H, Gmeiner B, Wagner O, Kapitotis S, Frass M, Kaye AD. Inhibitory effect of omeprazole on transmigration of leukocytes through endothelial cell monolayer and leukocyte adhesion. Microvasc Res 2000; 59: 169-71.
    • (2000) Microvasc Res , vol.59 , pp. 169-171
    • Holbauer, R.1    Loset, H.2    Gmeiner, B.3    Wagner, O.4    Kapitotis, S.5    Frass, M.6    Kaye, A.D.7
  • 24
    • 0030611919 scopus 로고    scopus 로고
    • A United State multicentre trial of dual and proton pump inhibitor-based triple therapies for Helicobacter pylori
    • Laine L, Frantz JE, Baker A, Neil GA. A United State multicentre trial of dual and proton pump inhibitor-based triple therapies for Helicobacter pylori. Aliment Pharmacol Ther 1997; 11: 913-7.
    • (1997) Aliment Pharmacol Ther , vol.11 , pp. 913-917
    • Laine, L.1    Frantz, J.E.2    Baker, A.3    Neil, G.A.4
  • 25
    • 0035046752 scopus 로고    scopus 로고
    • Peptic ulcer occurrence on follow-up of chronic gastritis in patients with treated and not eradicated CagA-positive Helicobacter pyroli infection
    • Carratue R, Iuliano D, Iovene MR, Ferraracio F, Esposito P, Russo MI, Montella F, Abbate G, Tufano MA. Peptic ulcer occurrence on follow-up of chronic gastritis in patients with treated and not eradicated CagA-positive Helicobacter pyroli infection. Dig Dis Sci 2001; 46: 581-6.
    • (2001) Dig Dis Sci , vol.46 , pp. 581-586
    • Carratue, R.1    Iuliano, D.2    Iovene, M.R.3    Ferraracio, F.4    Esposito, P.5    Russo, M.I.6    Montella, F.7    Abbate, G.8    Tufano, M.A.9
  • 28
    • 0033397014 scopus 로고    scopus 로고
    • Helicobacter pylori extracts reduce gastric mucosal blood flow by a nitric oxide-independent but mast cell- and platelet-activating factor receptor-dependent pathway in rats
    • Atuma C, Engstrand L, Holm L. Helicobacter pylori extracts reduce gastric mucosal blood flow by a nitric oxide-independent but mast cell- and platelet-activating factor receptor-dependent pathway in rats. Scand J Gastroenterol 1999; 34: 1183-9.
    • (1999) Scand J Gastroenterol , vol.34 , pp. 1183-1189
    • Atuma, C.1    Engstrand, L.2    Holm, L.3
  • 29
    • 0030814280 scopus 로고    scopus 로고
    • Relationship between changes of active oxygen metabolism and blood flow and formation, progression, and recovery of lesions in gastric mucosa of rats with a single treatment of compound 48/80, a mast cell degranulator
    • Ohta Y, Kobayashi T, Nishida K, Ishiguro I. Relationship between changes of active oxygen metabolism and blood flow and formation, progression, and recovery of lesions in gastric mucosa of rats with a single treatment of compound 48/80, a mast cell degranulator. Dig Dis Sci 1997; 42: 1221-32.
    • (1997) Dig Dis Sci , vol.42 , pp. 1221-1232
    • Ohta, Y.1    Kobayashi, T.2    Nishida, K.3    Ishiguro, I.4
  • 30
    • 0032833007 scopus 로고    scopus 로고
    • Participation of xanthine-xanthine oxidase system and neutrophils in development of acute gastric mucosal lesions in rats with a single treatment of compound 48/80, a mast cell degranulator
    • Ohta Y, Kobayashi T, Ishiguro I. Participation of xanthine-xanthine oxidase system and neutrophils in development of acute gastric mucosal lesions in rats with a single treatment of compound 48/80, a mast cell degranulator. Dig Dis Sci 1999; 44: 1865-74.
    • (1999) Dig Dis Sci , vol.44 , pp. 1865-1874
    • Ohta, Y.1    Kobayashi, T.2    Ishiguro, I.3
  • 31
    • 0033119707 scopus 로고    scopus 로고
    • Role of endogenous serotonin and histamine in the pathogenesis of gastric mucosal lesions in unanesthetised rats with a single treatment of compound 48/80, a mast cell degranulator
    • Ohta Y, Kobayashi T, Ishiguro I. Role of endogenous serotonin and histamine in the pathogenesis of gastric mucosal lesions in unanesthetised rats with a single treatment of compound 48/80, a mast cell degranulator. Pharmacol Res 1999; 39: 261-7.
    • (1999) Pharmacol Res , vol.39 , pp. 261-267
    • Ohta, Y.1    Kobayashi, T.2    Ishiguro, I.3
  • 32
    • 0021742157 scopus 로고
    • Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models
    • Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344-50.
    • (1984) Gastroenterology , vol.87 , pp. 1344-1350
    • Krawisz, J.E.1    Sharon, P.2    Stenson, W.F.3
  • 34
    • 0020550892 scopus 로고
    • Assay method for myeloperoxidase in human polymorphonuclear leukocytes
    • Suzuki K, Ota H, Sasagawa S, Sakatani T, Fujikura T. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Anal Biochem 1983; 132: 345-53.
    • (1983) Anal Biochem , vol.132 , pp. 345-353
    • Suzuki, K.1    Ota, H.2    Sasagawa, S.3    Sakatani, T.4    Fujikura, T.5
  • 35
    • 0016320450 scopus 로고
    • New spectrophotometric assay method of xanthine oxidase in crude tissue homogenate
    • Hashimoto S. New spectrophotometric assay method of xanthine oxidase in crude tissue homogenate. Anal Biochem 1974; 62: 426-33.
    • (1974) Anal Biochem , vol.62 , pp. 426-433
    • Hashimoto, S.1
  • 36
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 37
    • 0014428865 scopus 로고
    • Estimation of total, protein-bound, and non-protein sulfhydryl groups in tissue with Ellman's reagent
    • Sedlak J, Lindsay RH. Estimation of total, protein-bound, and non-protein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 1968; 25: 192-205.
    • (1968) Anal Biochem , vol.25 , pp. 192-205
    • Sedlak, J.1    Lindsay, R.H.2
  • 38
    • 0001637605 scopus 로고
    • Rapid determination for the hexosamine content as an indicator of the mucus glycoproteins in biopsy sample from alimentary track
    • Oketani K, Murakami M, Fujisawa H, Wakabayashi T. Rapid determination for the hexosamine content as an indicator of the mucus glycoproteins in biopsy sample from alimentary track. J Clin Exp Med (Igaku no Ayumi) 1984; 131: 745-9.
    • (1984) J Clin Exp Med (Igaku no Ayumi) , vol.131 , pp. 745-749
    • Oketani, K.1    Murakami, M.2    Fujisawa, H.3    Wakabayashi, T.4
  • 39
    • 0022486983 scopus 로고
    • A simple method for estimation of gastric mucus and effects of antiulcernogenic agents on the decrease in mucus during water-immersion stress in rats
    • Kitagawa H, Takada F, Kohei H. A simple method for estimation of gastric mucus and effects of antiulcernogenic agents on the decrease in mucus during water-immersion stress in rats. Arzneim Forsch/Drug Res 1986; 36: 1240-4.
    • (1986) Arzneim Forsch/Drug Res , vol.36 , pp. 1240-1244
    • Kitagawa, H.1    Takada, F.2    Kohei, H.3
  • 40
    • 0023713747 scopus 로고
    • Simultaneous micro-determination of serotonin and 5-hydroxyindole-3-acetic acid with 5-hydroxy-Nω-methyltryptamine, as an internal standard, in biological materials by high-performance liquid chromatography with electrochemical detection
    • Shibata K, Onodera M, Kawada T, Iwai K. Simultaneous micro-determination of serotonin and 5-hydroxyindole-3-acetic acid with 5-hydroxy-Nω-methyltryptamine, as an internal standard, in biological materials by high-performance liquid chromatography with electrochemical detection. J Chromatogr 1988; 430: 381-7.
    • (1988) J Chromatogr , vol.430 , pp. 381-387
    • Shibata, K.1    Onodera, M.2    Kawada, T.3    Iwai, K.4
  • 42
    • 0344731887 scopus 로고
    • A method for the fluorometric assay of histamine in tissues
    • Shore PA, Burkhalter A, Cohn VH Jr. A method for the fluorometric assay of histamine in tissues. J Phamacol Exp Ther 1959; 127: 182-6.
    • (1959) J Phamacol Exp Ther , vol.127 , pp. 182-186
    • Shore, P.A.1    Burkhalter, A.2    Cohn V.H., Jr.3
  • 43
    • 0025719438 scopus 로고
    • Role of in vitro- and in vivo-administered histamine and serotonin in compound 48/80-induced gastric acid secretion in isolated perfused rat stomach
    • Hus HC, Flancaum LJ, Kasziba E, Merril GF, Fischer H. Role of in vitro- and in vivo-administered histamine and serotonin in compound 48/80-induced gastric acid secretion in isolated perfused rat stomach. Dig Dis Sci 1991; 36: 1708-14.
    • (1991) Dig Dis Sci , vol.36 , pp. 1708-1714
    • Hus, H.C.1    Flancaum, L.J.2    Kasziba, E.3    Merril, G.F.4    Fischer, H.5
  • 44
    • 0022587471 scopus 로고
    • Pathogenesis of compound 48/80-induced gastric mucosal lesions in rats
    • Takeuchi K, Ohtsuki H, Okabe S. Pathogenesis of compound 48/80-induced gastric mucosal lesions in rats. Dig Dis Sci 1986; 31: 392-400.
    • (1986) Dig Dis Sci , vol.31 , pp. 392-400
    • Takeuchi, K.1    Ohtsuki, H.2    Okabe, S.3
  • 45
    • 0023110502 scopus 로고
    • Effects of omeprazole on gastric mucosal microcirculation and acid secretion in the rat
    • Holm-Rutili L. Effects of omeprazole on gastric mucosal microcirculation and acid secretion in the rat. Gastroenterology 1987; 92: 716-23.
    • (1987) Gastroenterology , vol.92 , pp. 716-723
    • Holm-Rutili, L.1
  • 46
  • 48
    • 0023278545 scopus 로고
    • Effects of omeprazole on gastric mucosal blood flow in the conscious rat
    • Mattsson H, Larsson H. Effects of omeprazole on gastric mucosal blood flow in the conscious rat. Scand J Gastroenterol 1987; 22: 491-8.
    • (1987) Scand J Gastroenterol , vol.22 , pp. 491-498
    • Mattsson, H.1    Larsson, H.2
  • 49
    • 0035794020 scopus 로고    scopus 로고
    • Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80
    • Kobayashi T, Ohta Y, Yoshino J. Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80. Eur J Pharmacol 2001; 412: 271-9.
    • (2001) Eur J Pharmacol , vol.412 , pp. 271-279
    • Kobayashi, T.1    Ohta, Y.2    Yoshino, J.3
  • 51
    • 0018628604 scopus 로고
    • High concentrations of glutathione in glandular stomachs. Possible implication for carcinogenesis
    • Boyd SC, Sasame HA, Boyd MR. High concentrations of glutathione in glandular stomachs. Possible implication for carcinogenesis. Science 1979; 205: 1010-2.
    • (1979) Science , vol.205 , pp. 1010-1012
    • Boyd, S.C.1    Sasame, H.A.2    Boyd, M.R.3
  • 52
    • 0024998259 scopus 로고
    • Gastric mucosal injury caused hemorrhagic shock and reperfusion: Protective role of the antioxidant glutathione
    • Stein HJ, Hinder RA, Oosthuizen MMJ. Gastric mucosal injury caused hemorrhagic shock and reperfusion: Protective role of the antioxidant glutathione. Surgery 1990; 108: 467-74.
    • (1990) Surgery , vol.108 , pp. 467-474
    • Stein, H.J.1    Hinder, R.A.2    Oosthuizen, M.M.J.3
  • 53
    • 12644298684 scopus 로고    scopus 로고
    • Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide
    • Casini A, Ceni E, Salano R, Biondi P, Parola M, Call A, Foschi M, Caligiuri A, Pinzani M, Surrent C. Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide. Hepatology 1997; 25: 361-7.
    • (1997) Hepatology , vol.25 , pp. 361-367
    • Casini, A.1    Ceni, E.2    Salano, R.3    Biondi, P.4    Parola, M.5    Call, A.6    Foschi, M.7    Caligiuri, A.8    Pinzani, M.9    Surrent, C.10
  • 54
    • 0030869662 scopus 로고    scopus 로고
    • Neutrophil-mediated phospholipid peroxidation assessed by gas chromatography-mass spectroscopy
    • Zimmerman JJ, Ciesielski W, Lewandoski J. Neutrophil-mediated phospholipid peroxidation assessed by gas chromatography-mass spectroscopy. Am J Physiol 1997; 273: C653-61.
    • (1997) Am J Physiol , vol.273
    • Zimmerman, J.J.1    Ciesielski, W.2    Lewandoski, J.3
  • 55
    • 0023831573 scopus 로고
    • Peroxidation of phospholipid promoted by myeloperoxidase
    • Carlin GR, Djursater R. Peroxidation of phospholipid promoted by myeloperoxidase. Free Radic Res Commun 1988; 4: 251-7.
    • (1988) Free Radic Res Commun , vol.4 , pp. 251-257
    • Carlin, G.R.1    Djursater, R.2
  • 56
  • 57
    • 0022502428 scopus 로고
    • Xanthine oxidase: Biochemistry, distribution and physiology
    • Parks DA, Granger DN. Xanthine oxidase: Biochemistry, distribution and physiology. Acta Physiol Scand 1986; 548(Suppl): 87-99.
    • (1986) Acta Physiol Scand , vol.548 , Issue.SUPPL. , pp. 87-99
    • Parks, D.A.1    Granger, D.N.2
  • 58
    • 0027965461 scopus 로고
    • Effect of NC-1300-O-3 on gastric mucus secretion and prostaglandin release in rats
    • Matsukura H, Masuda M, Uchida A, Kamishiro T. Effect of NC-1300-O-3 on gastric mucus secretion and prostaglandin release in rats. Jpn J Pharmacol 1994; 65: 319-26.
    • (1994) Jpn J Pharmacol , vol.65 , pp. 319-326
    • Matsukura, H.1    Masuda, M.2    Uchida, A.3    Kamishiro, T.4
  • 59
    • 0028013354 scopus 로고
    • Effects of acid-inhibitory antiulcer drugs on mucin biosynthesis in the stomach
    • Ichikawa T, Ishihara K, Saigenji K, Hotta K. Effects of acid-inhibitory antiulcer drugs on mucin biosynthesis in the stomach. Eur J Pharmacol 1994; 251: 107-11.
    • (1994) Eur J Pharmacol , vol.251 , pp. 107-111
    • Ichikawa, T.1    Ishihara, K.2    Saigenji, K.3    Hotta, K.4


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