CD44 co-stimulates apoptosis in thymic lymphomas and T cell hybridomas

Cellular Immunology

Volumn 216, Issue 1-2, 2002, Pages 82-92

  Guy, R ^a   Yefenof, E ^a   Naor, D ^a   Dorogin, A ^a   Zilberman, Y ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

Adhesion molecules; Apoptosis; CD44; Glucocorticoids; Thymic lymphomas

Indexed keywords

CELL ADHESION MOLECULE; DEXAMETHASONE; GLUCOCORTICOID; HERMES ANTIGEN; IMMOBILIZED ANTIBODY; PROTEIN BAX; PROTEIN BCL XL;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DIMERIZATION; EPITHELIUM CELL; HYBRIDOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMUS; THYMUS LYMPHOMA;

ANIMALS; ANTIGENS, CD44; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CLONE CELLS; COCULTURE TECHNIQUES; DEXAMETHASONE; DIMERIZATION; DOWN-REGULATION; EPITHELIAL CELLS; GLUCOCORTICOIDS; HYBRIDOMAS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; THYMUS GLAND; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0036399025     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-8749(02)00505-1     Document Type: Article

References (45)

1. H. Von Boehmer, H.S. Teh, P. Kisielow, The thymus selects the useful, neglects the useless and destroys the harmful, Immunol. Today 10 (1989) 57-61.
2. J. Sprent, D. Lo, E.K. Gao, Y. Ron, T cell selection in the thymus, Immunol. Rev. 101 (1988) 173-190.
3. Y.F. Shi, R.P. Bissonnette, N. Parfrey, M. Szalay, R.T. Kubo, D.R. Green, In vivo administration of mAbs to the CD3 TCR complex induces cell death (apoptosis) in immature thymocytes, J. Immunol. 146 (1991) 3340-3346.
4. L.B. King, M.S. Vacchio, K. Dixon, R. Hunziker, D.H. Margulis, J.D. Ashwell, A targeted glucocorticoid receptor antisence transgene increases thymocyte apoptosis and alters thymocyte developmet, Immunity 3 (1995) 647-656.
5. J. Gruber, R. Sgonc, H.Y. Hua, H. Beug, G. Wick, Thymocyte apoptosis induced by elevated endogenous corticosterone levels, Eur. J. Immunol. 24 (1994) 1115-1121.
6. M.S. Vacchio, V. Papadopoulos, J.D. Ashwell, Steroid production in the thymus: implications for thymocyte selection, J. Exp. Med. 179 (1994) 1835-1846.
7. O.L. Lechner, G.J. Wiegers, A.J. Oliveira-dos-Santos, H. Dietrich, H. Recheils, M. Waterman, R. Boyd, G. Wick, Glucocorticoid production in the murine thymus, Eur. J. Immunol. 30 (2000) 337-346.
8. A. Pazirandeh, Y. Xue, I. Rafter, J. Sjovall, M. Jondal, S. Okret, Paracrine glucocorticoid activity produced by mouse thymic epithelial cells, FASEB J. 13 (1999) 893-901.
9. M. Iwata, S. Hanaoka, K. Sato, Rescue of thymocytes and T cell hybridomasfrom GC-induced apoptosis by stimulation via the TCR/CD3 complex: a possible in vitromodel for positive selection of the T cell repertoire, Eur. J. Immunol. 21 (1991) 643-648.
10. C.M. Zacharchuk, M. Mercep, P.K. Chakraborti, S.S. Simons Jr., J.D. Ashwell, Programmed T lymphocytes death. Cell activation and steroid-induced pathways are mutually antagonistic, J. Immunol. 145 (1990) 4037-4045.
11. Y. Zilberman, E. Yefenof, E. Oron, A. Dorogin, R. Guy, T cell receptor-independent apoptosis of thymocyte clones induced by a thymic epithelial cell line is mediated by steroids, Cell. Immunol. 170 (1996) 78-84.
12. R. Guy, I. Gafanovitch, N. Rosenheimer, E. Oron, A. Dorogin, E. Yefenof, Y. Zilberman, MHC non-restricted, CD95 independent apoptosis of immature thymocytes induced by thymic epithelial cells, Cell Death Diff. 3 (1996) 431-438.
13. E. Ayroldi, G. Migliorati, L. Cannarile, R. Moraca, D.V. Delfino, C. Riccardi, CD2 rescues T cells from TCR/CD3 apoptosis: a role for the Fas/FasL system, Blood 89 (1997) 3717-3726.
14. H.C. DeGrendele, M. Kosfiszer, P. Estess, M.H. Siegelman, CD44 activation and associated primary adhesion is inducible via TCR stimulation, J. Immunol. 159 (1997) 2549-2553.
15. Y. Shimizu, G.A. Van Sventer, R. Siraganian, L. Wahl, S. Shaw, Dual role of the CD44 molecule in T cell adhesion and activation, J. Immunol. 143 (1989) 2457-2463.
16. S. Huet, H. Groux, B. Calliou, H. Valentin, A.M. Prieur, A. Bernard, CD44 contributes to T cell activation, J. Immunol. 143 (1989) 798-801.
17. S.M. Denning, P.T. Le, K.H. Singer, B.F. Haynes, Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation, J. Immunol. 144 (1990) 7-15.
18. E. Ayroldi, L. Cannarile, G. Migliorati, A. Bartoli, I. Nicoletti, C. Riccardi, CD44 (PgP1) inhibits CD3 and dexamethasone-induced apoptosis, Blood 86 (1995) 2672-2678.
19. D.G. Maloney, M.S. Kaminski, D. Burowski, J. Haimovich, R. Levy, Monoclonal anti-idiotype antibodies against the murine B cell lymphoma 38C13: characterization and use as probes for the biology of the tumor in vivo and in vitro, Hybridoma 4 (1985) 191-209.
20. Y. Ben David, E. Yefenof, M. Kotler, Clonal analysis of radiation leukemia virus-induced leukemic and preleukemic murine cells, Cancer Res. 47 (1987) 6590-6594.
21. S.M. Hedrick, L.A. Matis, T.T. Hecht, L.E. Samelson, D.L. Longo, E. Heber-Katz, R.H. Schwartz, The fine specificity of antigen and Ia determinant recognition by cell hybridoma clones specific for pigeon cytochrome c, Cell 30 (1982) 141-152.
22. M.A. Zahalka, E. Okon, U. Gosslar, B. Holzmann, D. Naor, Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and Hyaluronate-dependent, J. Immunol. 154 (1995) 5345-5355.
23. L.H. Glimcher, A.M. Kruisbeek, W.E. Paul, I. Green, Functional activity of a transformed thymic epithelial cell line, Scand. J. Immunol. 17 (1983) 1-11.
24. I. Nicoletti, G. Migliorati, M.C. Pagliacci, F. Grignani, C. Riccardi, A rapid and simple method for measuring thymocytes apoptosis by propidium iodide staining and flow cytometyry, J. Immunol. Methods 139 (1991) 271-279.
25. I. Vermes, C. Haanen, H. Steffens-Nakken, C. Reutelingsperger, A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin-V, J. Immunol. Methods 184 (1995) 39-51.
26. S.A. Ben-Sasson, Y. Sherman, Y. Gavrieli, Identification of dying cells-in situ staining, Methods. Cell. Biol. 46 (1995) 29-39.
27. Y. Haupt, S. Rowan, E. Shaulian, K.H. Vousden, M. Oren, Induction of apoptosis in HeLa cells by trans-activation-deficient p53, Genes Dev. 9 (1995) 2170-2183.
28. + thymocytes is p53-independent, Cell Death Differ. 7 (2000) 241-249.
29. 2 withdrawal, J. Immunol. 155 (1995) 2311-2317.
30. 2 repress a common pathway of cell death, J. Exp. Med. 182 (1995) 821-828.
31. L during apoptosis, Proc. Natl. Acad. Sci. 94 (1997) 3668-3672.
32. K.G. Wolter, Y.T. Hsu, C.L. Smith, A. Nechushtan, X.G. Xi, R.J. Youle, Movement of Bax from the cytosol to mitochondria during apoptosis, J. Cell. Biol. 139 (1997) 1281-1292.
33. 2 counters apoptosis by Bax heterodimerization-dependent and independent mechanisms in the T cell lineage, J. Biol. Chem. 272 (1997) 29347-29355.
34. + thymocytes in vitro does not require dedicated antigen presenting cells, Eur. J. Immunol. 23 (1993) 669-674.
35. S. Vukmanovic, S.C. Jameson, M.J. Bevan, A thymic epithelial cell line induces both positive and negative selection in the thymus, Int. Immunol. 6 (1994) 239-246.
36. M. Nakashima, K. Mori, K. Maeda, H. Kishi, K. Hirata, M. Kawabuchi, T. Watanabe, Selective elimination of double-positive immature thymocytes by a thymic epithelial cell line, Eur. J. Immunol. 20 (1990) 47-53.
37. J. Lesley, R. Hyman, P.W. Kincade, CD44 and its interaction with extracellular matrix, Adv. Immunol. 54 (1993) 271-335.
38. D. Naor, R. Vogt-Sionov, D. Ish-Shalom, CD44: structure, function and association with the malignant process, Adv. Cancer Res. 71 (1997) 241-319.
39. N. Kawakami, F. Nishizawa, N. Sakane, M. Iwao, K. Tsujikawa, M. Ikawa, M. Okabe, H. Yamamoto, Roles of integrins and CD44 on the adhesion and migration of fetal liver cells to the fetal thymus, J. Immunol. 163 (1999) 3211-3216.
40. R. Galandrini, N. Albi, A. Vecchiarelli, R. Tognellini, D. Zarcone, C.E. Grossi, Velardi, A Ligation of the lymphocyte homing receptor CD44 triggers T helper and cytolytic functions of human T cells, Cytotechnology 11 (Suppl. 1) (1993) S100-S102.
41. N. Foger, R. Marhaba, M. Zoller, CD44 supports T cell proliferation and apoptosis by apposition of protein kinases, Eur. J. Immunol. 30 (2000) 2888-2899.
42. K. Fujii, Y. Fujii, S. Hubscher, Y. Tanaka, CD44 is the physiological trigger of Fas up-regulation on Rheumatoid Synovial cells, J. Immunol. 167 (2001) 1198-1203.
43. C. Henke, P. Bitterman, U. Roongta, D. Ingbar, V. Polunovsky, Induction of fibroblast apoptosis by anti-CD44 antibody: Implications for the treatment of fibroproliferative lung disease, Am. J. Pathol. 149 (1996) 1639-1650.
44. B. Tian, T. Takasu, C. Henke, Functional role of cyclin A on induction of fibroblast apoptosis due to ligation of CD44 matrix receptor by anti-CD44 antibody, Exp. Cell. Res. 257 (2000) 135-144.
45. K. Takazoe, G.H. Tesch, P.A. Hill, L.A. Hurst, Z. Jun, H.Y. Lan, R.C. Atkins, D.J. Nikolic-Paterson, CD44-mediated neutrophil apoptosis in the rat, Kidney Int. 58 (2000) 1920-1930.