A repeated 28-day oral dose toxicity study of genistein in rats, based on the 'Enhanced OECD Test Guideline 407' for screening endocrine-disrupting chemicals

Archives of Toxicology

Volumn 76, Issue 10, 2002, Pages 553-559

  Okazaki, Kazushi ^a   Okazaki, Shuzo ^b   Nakamura, Hideaki ^b   Kitamura, Yasuki ^b   Hatayama, Kazuhisa ^b   Wakabayashi, Sachiko ^b   Tsuda, Toshiharu ^b   Katsumata, Tomoyoshi ^b   Nishikawa, Akiyoshi ^a   Hirose, Masao ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b BoZo Research Center Inc   (Japan)

Author keywords

Endocrine disrupter; Enhanced OECD Test Guideline 407; Genistein; Phytoestrogen; Rat

Indexed keywords

GENISTIN; GENISTEIN; HORMONE ANTAGONIST; PROLACTIN;

ANIMAL CELL; ARTICLE; BLOOD CHEMISTRY; CONTROLLED STUDY; ELECTRIC POTENTIAL; ESTRUS CYCLE; EVALUATION; FEEDING; FEMALE; HISTOPATHOLOGY; HORMONE BLOOD LEVEL; LIVER CELL; LIVER WEIGHT; MALE; MEDICAL RECORD; NONHUMAN; PRIORITY JOURNAL; RAT; SCREENING; SPERM; TOXICITY; TOXICITY TESTING; ANIMAL; BLOOD; BLOOD ANALYSIS; DOSE RESPONSE; DRUG EFFECT; DRUG SURVEILLANCE PROGRAM; EUROPEAN UNION; FEMALE GENITAL SYSTEM; MALE GENITAL SYSTEM; MOTOR ACTIVITY; ORAL DRUG ADMINISTRATION; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; RAT STRAIN; SPERMATOZOON;

ANIMALIA;

ADMINISTRATION, ORAL; ANIMALS; BLOOD CHEMICAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROUS CYCLE; EUROPEAN UNION; FEMALE; GENISTEIN; GENITALIA, FEMALE; GENITALIA, MALE; HORMONE ANTAGONISTS; MALE; MOTOR ACTIVITY; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PROLACTIN; RATS; RATS, INBRED STRAINS; SPERMATOZOA;

EID: 0036392560     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0376-0     Document Type: Article

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