Oral folic acid improves endothelial dysfunction in cigarette smokers

Journal of Surgical Research

Volumn 106, Issue 2, 2002, Pages 342-345

  O'grady H L ^a   Leahy, A ^a   McCormick, P H ^a   Fitzgerald, P ^a   Kelly, C ^a   Bouchier Hayes, D J ^a  

^a BEAUMONT HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE;

ADULT; ATHEROGENESIS; CHOLESTEROL BLOOD LEVEL; CIGARETTE SMOKING; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ECHOGRAPHY; ENDOTHELIUM LESION; HEMATOLOGICAL PARAMETERS; HUMAN; LIPID ANALYSIS; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; VASCULAR ENDOTHELIUM; VASODILATATION; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

EID: 0036392164     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.2002.6467     Document Type: Article

References (25)

1. Zhu, B. Q., Sun, Y. P., Sievers, R. E., Isenberg, W. M., Glantz, S. A., and Parmley, W. W. Passive smoking increases experimental atherosclerosis in cholesterol-fed rabbits. J. Am. Coll. Cardiol. 21: 225, 1993.
2. Hoffmann, D. Tobacco and Tobacco Smoke. New York: Academic Press, 1967.
3. Drexler, H. Endothelial dysfunction: Clinical implications. Prog. Cardiovasc. Dis. 39: 287, 1997.
4. Anderson, T. J., Uehata, A., Gerhard, M. D., et al. Close relation of endothelial function in the human coronary and peripheral circulations. J. Am. Coll. Cardiol. 26: 1235, 1995.
5. Celermajer, D. S., Sorensen, K. E., Georgakopoulos, D., Bull, C., Thomas, O., Robinson, J., and Deanfield, J. E. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation 88: 2149-55, 1993.
6. Celermajer, D. S., Adams, M. R., Clarkson, P., Robinson, J., McCredie, R., Donald, A., and Deanfield, J. E. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N. Engl. J. Med. 334: 150, 1996.
7. Chasan-Taber, L., Selhub, J., Rosenberg, I. H., Malinow, R., Terry, P., Tishler, P. V., Willet, W., Hennekens, C. H., and Stampfer, M. J. A prospective study of folate and vitamin B6 and risk of myocardial infarction in US physicians. J. Am. Coll. Nutr. 15(2): 136, 1996.
8. Robinson, K., Arheart K., Refsum, H., Brattstrom, L., Boers, G., Ueland, P., Rubba, P., Palma-Reis, R., Meleady, R., Daly, L., Witteman, J., and Graham, I. Low circulating folate and vitamin B6 concentrations. Risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC group. Circulation 97: 437, 1998.
9. Pancharunti, N., Lewis, C. A., and Sauberlich, H. E. Plasma homocysteine, folate, and vitamin B12 concentration and risk for early-onset coronary artery disease. Am. J. Clin. Nutr. 59: 940, 1994.
10. Stampfer, M. J., Malinow, M. R., Willett, W. C., Newcomer, L. M., Upson, B., Ullmann, D., Tishler, P. V., and Hennekens, C. H. A prospective study of plasma homocysteine and risk of myocardial infarction in US physicians. J. Am. Med. Assoc. 268: 877, 1992.
11. Selhub, J., Jacques, P. F., and Bostom, A. G. Association between plasma homocysteine concentration and extra-cranial carotid stenosis. N. Engl. J. Med. 332: 286, 1995.
12. Ubbink, J. B. The role of vitamins in the pathogenesis and treatment of hyperhomocysteinemia. J. Inherit. Metab. Dis. 20: 316, 1997.
13. Celemajer, D. S., Sorensen, K. E., Goch, V. M., et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 340: 1111, 1992.
14. Sorensen, K. E., Celermajer, D. S., Spiegelhalter, D. J., Georgakopoulos, D., Robinson, J., Thomas, O., and Deanfield, J. E. Non-invasive measurement of human endothelium dependent arterial responses: accuracy and reproducibility. Br. Heart J. 74: 247, 1995.
15. Joannides, R., Haefeli, W. E., Linder, L., et al. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 91: 1314, 1995.
16. Schroeder, S., Enderle, M., Ossen, R., Meisner, C., Baumbach, A., Pfohl, M., Herdeg, C., Oberhoff, M., Haering, H., and Karsch, K. Non-invasive determination of endothelium-mediated vasodilatation as a screening test for coronary artery disease: Pilot study to assess the predictive value in comparison with angina pectoris, exercise electrocardiography, and myocardial perfusion imaging. Am. Heart J. 138(4): 731, 1999.
17. Xia, Y., Tsai, H. L., and Zweier, J. L. Ca/calmodulin dependent superoxide generation by endothelial nitric oxide synthase. Circulation 96: 1281A, 1997.
18. Stroes, E. S. G., Hijmering, M., Zandvoort, M., Rabelink, T. J., and Faasen, E. E. Origin of superoxide production by nitric oxide synthase. FEBS Lett. 438: 161, 1998.
19. Pritchard, K. A., Groszek, L., Smalley, D. M., Sessa, W. C., Wu, M., Villalan, P., Wolin, M. S., and Stemerman, M. B. Native low density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ. Res. 77: 510, 1995.
20. Ohara, Y., Perteson, T. E., Sayegh, H. S., Subramanian, R. R., Wilcox, J. N., and Harrison, D. G. Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production. Circulation 92: 898, 1995.
21. Harrison, D. G., and Ohara, Y. Physiologic consequences of increased vascular oxidant stresses in hypercholesterolemia and atherosclerosis: Implications for impaired vasomotion. Am. J. Cardiol. 75: 75B, 1995.
22. Ohara, Y., Peterson, T. E., and Harrison, D. G. Hypercholesterolemia increases endothelial superoxide anion production. J. Clin. Invest. 91: 2546, 1993.
23. Woo, K. S., Chook, P., Lolin, Y. I., Chan L. T., Sun, Y. Y., Sanderson, J. E., Metraveli, C., and Celemajer, D. S. Hyperhomocysteinemia is a risk factor for arterial endothelial dysfunction in humans. Circulation 96: 2542, 1997.
24. Ridker, P. M., Stampfer, M. J., and Rifai, N. Novel risk factors for atherosclerosis. A comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(A), and standard cholesterol screening as predictors of peripheral arterial disease. J. Am. Med. Assoc. 285: 2481, 2001.
25. Stroes, E. S. G., van Fassen, E. E., Martasek, M., Boer, P., and Rabelink, T. J. Folic acid reverts dysfunction of endothelial nitric oxide synthase. Circ. Res. 86: 1129, 2000.