Reversal of P-glycoprotein-mediated multidrug resistance by 5,6,7,3′,4′-pentamethoxyflavone (Sinensetin)

Biochemical and Biophysical Research Communications

Volumn 295, Issue 4, 2002, Pages 832-840

  Choi, Cheol Hee ^a,c   Sun, Kyung Hoon ^a   An, Chun San ^a   Yoo, Jin Cheol ^a   Hahm, Kyung Soo ^a   Lee, In Hwa ^a   Sohng, Jae Kyung ^b   Kim, Youn Chul ^b  

^a Chosun University   (South Korea)

^b SunMoon University   (South Korea)

^c Kolon Industries Inc   (South Korea)

Author keywords

Azidopine; Chemosensitizer; Flavonoid; Multidrug resistance; P Glycoprotein; Sinensetin

Indexed keywords

3,5,7 TRIHYDROXY 3',4',5' TRIMETHOXYFLAVONE; 3,6,3',4' TETRAMETHOXYFLAVONE; 3,7 DIHYDROXY 3',4' DIMETHOXYFLAVONE; 5,6,7,3',4' PENTAMETHOXYFLAVONE; 5,7,3',4' TETRAMETHOXYFLAVONE; AZIDOPINE; BIRICODAR; CYCLOSPORIN A; FLAVONE DERIVATIVE; GLYCOPROTEIN P; LONAFARNIB; SINENSETIN; TACROLIMUS; TARIQUIDAR; UNCLASSIFIED DRUG; VALSPODAR; VERAPAMIL; VINCRISTINE; XR 9051; ZOSUQUIDAR;

ARTICLE; BINDING ASSAY; BINDING SITE; CELL LINE; CELL STRAIN; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG ACCUMULATION; DRUG BINDING; FLOW CYTOMETRY; IN VITRO STUDY; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; STRUCTURE ACTIVITY RELATION;

BLOTTING, WESTERN; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; FLAVONOIDS; HEMOLYSIS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; P-GLYCOPROTEIN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; QUERCETIN; RHODAMINE 123;

EID: 0036374158     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00755-6     Document Type: Article

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