A fluorescence assay for assessing chelation of intracellular iron in a membrane model system and in mammalian cells

Analytical Biochemistry

Volumn 233, Issue 2, 1996, Pages 221-227

  Cabantchik, Z Ioav ^a   Glickstein, Hava ^a   Milgram, Pnina ^a   Breuer, William ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BLOOD; CELLS; CHELATION; COBALT COMPOUNDS; COPPER COMPOUNDS; CYTOLOGY; DISEASE CONTROL; FLUORESCENCE; MAMMALS; METAL IONS; METAL RECOVERY; METALS; NICKEL COMPOUNDS; PERMEATION;

BIOCHEMICAL STUDIES; CELL MEMBRANE MODELS; DYNAMIC EQUILIBRIA; ERYTHROLEUKEMIA CELLS; FLUORESCENCE ASSAY; FLUORESCENT METHODS; INTRACELLULAR METALS; LOW MOLECULAR WEIGHT;

IRON COMPOUNDS;

SCAVENGER;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHELATION; COMPLEX FORMATION; ENCAPSULATION; ERYTHROLEUKEMIA CELL; FLUORESCENCE; IRON METABOLISM; IRON OVERLOAD; MEMBRANE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION;

ANIMALIA; MAMMALIA;

EID: 0030030821     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1996.0032     Document Type: Article

References (18)

1. Klausner, R. D., Rouault, T. A., and Harford, J. B. (1993) Cell 72, 19-281.
2. Crichton, R. R., and Ward, R. J. (1992) in Iron and Human Diseases (Laufer, R. B., Ed.), pp. 23-76, CRC Press, Boca Raton, FL.
3. Pollack, S. (1992) Am. J. Hematol. 39, 113-117.
4. Weaver, J., Zhan, H., and Pollack, S. (1993) Br. J. Hematol. 83, 138.
5. Rothman, R. J., Serroni, A., and Farber, J. L. (1992) Mol. Pharmacol. 42, 703-712.
6. Hershko, C., and Weatherall, D. J. (1988) CRC Crit. Rev. Clin. Lab. Sci. 26, 303-345.
7. Breuer, W., Epsztejn, S., and Cabantchik, Z. I. (1995) J. Biol. Chem. 270, 24207-24215.
8. Breuer, W., Epsztejn, S., Millgram, P., and Cabantchik, Z. I. (1995) Am. J. Physiol. 268, C1354-C1361.
9. Ponka, P., Grady, R. W., Wilczynska, A., and Schulman, H. M. (1984) Biochim. Biophys. Acta 802, 477-489.
10. Baker, E., Richardson, D., Gross, S., and Ponka, P. (1992) Hepatology 15, 492-501.
11. Hider, R. C., Porter, J. B., and Singh, S. (1994) in The Development of Iron Chelators for Clinical Use (Bergeron, R. J., and Brittenham, G. M., Eds.), pp. 353-372. CRC Press, Tokyo.
12. Hider, R. C., and Hall, A. D. (1991) in Progress in Medicinal Chemistry (Ellis, G. P., and West, G. B., Eds.), Vol. 28, pp. 40-173, Elsevier, London.
13. Hider, R. C., Singh, S., and Porter, J. B. (1992) Proc. R. Soc. Edinburgh B. 99(1/2), 137-168.
14. Loyevsky, M., Lytton, S., Meister, B., Libman, J., Shanzer, A., and Cabantchik, Z. I. (1993) J. Clin. Invest. 91, 218-224.
15. Shanzer, A., Libman, J., Lytton, S. D., and Cabantchik, Z. I. (1991) Proc. Natl. Acad. Sci. USA 88, 6585-6589.
16. Lytton, S. D., Mester, B., Dayan, I., Libman, J., Shanzer, A., and Cabantchik, Z. I. (1993) Blood 81, 214-221.
17. Tsafack, A., Golenser, J., Libman, J., Shanzer, A., and Cabantchik, Z. I. (1995) Mol. Pharmacol. 47, 403-409.
18. Cabantchik, Z. I. (1995) Parasitol. Today 11, 74-78.