Target cells for cytochrome P450-catalysed irreversible binding of 7,12-dimethylbenz[a]anthracene (DMBA) in rodent adrenal glands

Archives of Toxicology

Volumn 76, Issue 8, 2002, Pages 460-466

  Lindhe, Orjan ^a,b   Granberg, Lizette ^a   Brandt, Ingvar ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

7,12 Dimethylbenz a anthracene; Adrenal; Cytochrome P450 1A1 1B1; Irreversible binding; Tissue slice culture

Indexed keywords

1 ETHYNYLPYRENE; ALPHA NAPHTHOFLAVONE; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 1B1; CYTOCHROME P450 INHIBITOR; DIMETHYLBENZ[A]ANTHRACENE; ELLIPTICINE; METYRAPONE; TRITIUM; UNCLASSIFIED DRUG;

ADRENAL CORTEX; ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CATALYSIS; CELL ACTIVATION; CONTROLLED STUDY; DRUG BINDING; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; MOUSE; NONHUMAN; PARENCHYMA; PRIORITY JOURNAL; RAT; RETICULUM CELL; TARGET CELL; TOXICOKINETICS; ZONA FASCICULATA;

ANIMALIA; RODENTIA;

EID: 0036360903     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0367-1     Document Type: Article

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