Differences in nuclear retention characteristics of agonist-activated glucocorticoid receptor may determine specific responses

Experimental Cell Research

Volumn 276, Issue 2, 2002, Pages 142-154

  Vicent, Guillermo P ^a   Pecci, Adalí ^a   Ghini, Alberto ^a   Piwien Pilipuk, Graciela ^b   Galigniana, Mario D ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEXAMETHASONE; DIGITONIN; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE; MOLYBDIC ACID; PREGNA 1,4 11BETA OL 3,20 DIONE; STEROID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL PERMEABILIZATION; CHROMATIN; CONFORMATION; CONTROLLED STUDY; CYTOLYSIS; DOSE RESPONSE; DRUG EFFECT; LIGAND BINDING; MALE; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

EID: 0036352904     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2002.5532     Document Type: Article

References (46)

1. Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton
2. Evidence that the peptidylprolyl isomerase (PPlase) domain of the hsp90-binding immunophilin FKBP52 is a dynein interaction domain involved in glucocorticoid receptor movement to the nucleus
3. Protein-phosphatases type 1 and/or 2A regulate nucleocytoplasmic shuttling of glucocorticoid receptors
4. Tautomycin inhibits phosphatase-dependent transformation of the rat kidney mineralocorticoid receptor
5. Inhibition of glucocorticoids receptor nucleocytoplasmic shuttling by okadaic acid requires intact cytoskeleton
6. Steroid receptor interactions with heat shock protein and immunophilin chaperones
7. Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element
8. Two genetically defined transacting loci coordinately regulate overlapping sets of liver-specific genes
9. Steroid hormone receptors: Many actors in search of a plot
10. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
11. Transcription factor interactions: Selectors of positive or negative regulation from a single DNA element
12. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function
13. Characterization of a complex glucocorticoid response unit in the PEPCK gene
14. Inhibition of mouse GATA-1 function by the glucocorticoid receptor: Possible mechanism of steroid inhibition of erytroleukemia cell differentiation
15. Functional interactions between Stat-5 and the glucocorticoid receptor
16. Expression of the phosphoenolpyruvate carboxykinase gene in 3T3-F442A adipose cells: Opposite effects of dexamethasone and isoprenaline on transcription
17. Determinants of promoter-specific activity by glucocorticoid receptor
18. Glucocorticoids in T cell development and function
19. DNA binding of the glucocorticoid receptor is not essential for survival
20. Repression of inflammatory responses in the absence of DNA binding by glucocorticoid receptor
21. Apoptosis regulators and their role in tumorgenesis
22. A carbon-13 nuclear magnetic resonance study of the 1,4-diene analogues of steroid hormones and related steroids
23. The glucocorticoid properties of the synthetic steroid pregna-1,4-diene-11β-ol-3,20-dione (ΔHOP) are not entirely correlated with the steroid binding to the glucocorticoid receptor
24. Influence of calf serum on glucocorticoid-responses of certain progesterone derivatives
25. Anti-inflamatory activity of 11β-hydroxypregna-1,4-diene-3,20-dione
26. Appearance and persistence of 11β-hydroxypregna-1,4-diene-3,20-dione effect in vivo
27. 13C-NMR spectroscopy
28. Growth hormone regulates phosphorylation and function of CCAAT/Enhancer-binding protein β by modulating Akt and glycogen synthase kinase-3
29. S
30. Mechansim of action of the potent sodium-retaining steroid 11,19-oxidoprogesterone
31. Expression of epithelial phenotype is enhanced by v-Haras in rat endometrial cells immortalized by SV40-T antigen
32. Subnuclear trafficking of glucocorticoid receptors in vitro: Chromatin recycling and nuclear export
33. The glucocorticoid receptor: Rapid exchange with regulatory sites in living cells
34. Compartmentalization of regulatory proteins in the cell nucleus
35. Direct visualization of the human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptor
36. Subcellular localization of mineralocorticoid receptors in living cells: Effects of receptor agonists and antagonists
37. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
38. CCAAT/Enhancer-binding protein β (C/EBPβ) and C/EBPδ contribute to growth hormone-regulated transcription of c-fos
39. Interphase and metaphase resolution of different distances within the human dystrophin gene
40. Large scale chromatin unfolding and remodeling induced by VP16 acidic activation domain
41. Ultrastructural analysis of transcription and splicing in the cell nucleus after bromo-UTP microinjection
42. Localisation of rapidly and slowly labelled nuclear RNA as visualized by high resolution autoradiography
43. Active RNA polymerases are localized within discrete transcription 'factories' in human nuclei
44. Ultrastructural localization of active genes in nuclei of A431 cells
45. Nuclear distribution of transcription factors in relation to sites of transcription and RNA polymerase II