Substrate specificity of RusA resolvase reveals the DNA structures targeted by RuvAB and RecG in vivo

Molecular Cell

Volumn 10, Issue 1, 2002, Pages 187-198

  Bolt, Edward L ^a   Lloyd, Robert G ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HELICASE; PROTEIN RUVAB; RECG HELICASE; RESOLVASE; RUSA RESOLVASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; DNA CLEAVAGE; DNA STRUCTURE; ENZYME SPECIFICITY; ESCHERICHIA COLI; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; ULTRAVIOLET IRRADIATION;

ESCHERICHIA COLI;

EID: 0036348154     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00560-9     Document Type: Article

References (37)

1. Modulation of recombination and DNA repair by the RecG and PriA helicases of Escherichia coli K-12
2. Mus81-Eme1 are essential components of a Holliday junction resolvase
3. Identification of three aspartic acid residues essential for catalysis by the RusA Holliday junction resolvase
4. Defending genome integrity during DNA replication: A proposed role for RecQ family helicases
5. Sequence-specificity and biochemical characterization of the RusA Holliday junction resolvase of Escherichia coli
6. Human Mus81-associated endonuclease cleaves Holliday junctions in vitro
7. Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
8. Branch migration and Holliday junction resolution catalysed by activities from mammalian cells
9. The importance of repairing stalled replication forks
10. Formation of RuvABC-Holliday junction complexes in vitro
11. A role for MMS4 in the processing of recombination intermediates during meiosis in Saccharomyces cerevisiae
12. Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase
13. In vitro reconstitution of the late steps of genetic recombination in E. coli
14. Impairment of lagging strand synthesis triggers the formation of a RuvABC substrate at replication forks
15. Structural recognition and distortion by the DNA junction-resolving enzyme RusA
16. Direct rescue of stalled DNA replication forks via the combined action of PriA and RecG helicase activities
17. Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease
18. The Bloom's syndrome gene product promotes branch migration of Holliday junctions
19. Initiation of genetic recombination and recombination-dependent replication
20. PriA-directed assembly of a primosome on D loop DNA
21. Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82
22. Resolution of Holliday intermediates in recombination and DNA repair: Indirect suppression of ruvA, ruvB and ruvC mutations
23. Modulation of RNA polymerase by (p)ppGpp reveals a RecG-dependent mechanism for replication fork progression
24. Action of RuvAB at replication fork structures
25. Rescue of stalled replication forks by RecG: Simultaneous translocation on the leading and lagging strand templates supports an active DNA unwinding model of fork reversal and Holliday junction formation
26. Formation of Holliday junctions by regression of stalled replication forks: RecG stimulates fork regression even when the DNA is negatively supercoiled
27. Interaction of a four-way junction in DNA with T4 endonuclease VII
28. RecA protein promotes the regression of stalled replication forks in vitro
29. RuvAB acts at arrested replication forks
30. RuvABC-dependent double-strand breaks in dnaBts mutants require RecA
31. The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts
32. RusA proteins from the extreme thermophile Aquifex aeolicus and lactococcal phage r1t resolve Holliday junctions
33. Structural analysis of DNA replication fork reversal by RecG
34. Processing of recombination intermediates by the RuvABC proteins
35. Mechanism of E. coli RecA protein directed strand exchanges in post-replication repair of DNA
36. Interactions between RuvA and RuvC at Holliday junctions: Inhibition of junction cleavage and formation of a RuvA-RuvC-DNA complex
37. Coordinated actions of RuvABC in Holliday junction processing