Global ischemic neuronal damage relates to behavioural deficits: A pharmacological approach

Neuroscience

Volumn 82, Issue 3, 1997, Pages 791-803

  Block, F ^a,b   Schwarz, M ^b  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Behaviour; Cerebral ischemia; Rat; Water maze

Indexed keywords

DEXTROMETHORPHAN; EMOPAMIL; N METHYL DEXTRO ASPARTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIORAL SCIENCE; BRAIN ISCHEMIA; DISEASE ASSOCIATION; HIPPOCAMPUS; MAZE TEST; NERVE CONDUCTION; NERVE INJURY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0343632388     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00322-9     Document Type: Article

References (78)

1. Alps B. J., Calder C., Hass W. K. and Wilson A. D. (1988) Comparative protective effects of nicardipine, flunarizine, lidoflazine and nimodipine against ischemic injury in the hippocampus of the Mongolian gerbil. Br. J. Pharmac. 93, 877-883.
2. Apland J. P. and Braitman D. J. (1990) Effects of non-opioid antitussives on epileptiform activity and NMDA responses in hippocampal and olfactory cortex slices. Brain Res. 529, 277-285.
3. Araki T., Kato H., Kogure K. and Kanai Y. (1992) Long-term changes in gerbil brain neurotransmitter receptors following transient cerebral ischemia. Br. J. Pharmac. 107, 437-442.
4. Auer R. N., Jensen M. L. and Wishaw I. Q. (1989) Neurobehavioural deficit due to ischemic brain damage limited to half of the CA1 sector of the hippocampus. J. Neurosci. 9, 1641-1647.
5. Benveniste H., Drejer J., Schousboe A. and Diemer N. H. (1984) Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral micro-dialysis. J. Neurochem. 43, 1369-1374.
6. Block F., Jaspers R. M. A., Heim C. and Sontag K.-H. (1990) S-emopamil ameliorates ischemic brain damage in rats: histological and behavioural approaches. Life Sci. 47, 1511-1518.
7. Block F., Kunkel M. and Schwarz M. (1993) Quinolinic acid lesion of the striatum induces impairment in spatial learning and motor performance in rats. Neurosci. Lett. 149, 126-128.
8. Block F., Schmitt W. and Schwarz M. (1995) The antioxidant LY 231617 ameliorates functional and morphological sequelae induced by global ischemia in rats. Brain Res. 694, 308-311.
9. Block F., Schmitt W. and Schwarz M. (1996) Pretreatment but not posttreatment with GYKI 52466 reduces functional deficits and neuronal damage after global ischemia in rats. J. neurol. Sci. 139, 167-172.
10. Block F. and Schwarz M. (1993) N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of dextromethorphan in rats. NeuroReport 4, 941-943.
11. Block F. and Schwarz M. (1996) Memantine reduces functional and morphological consequences induced by global ischemia in rats. Neurosci. Lett. 208, 41-44.
12. Block F. and Schwarz M. (1996) Dextromethorphan reduces functional deficits and neuronal damage after global ischemia in rats. Brain Res. 741, 153-159.
13. Boast C. A., Gerhardt S. C., Pastor G., Lehmann J., Etienne P. E. and Liebmann J. M. (1988) The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils. Brain Res. 442, 345-348.
14. Bokesch P. M., Marchand J. E., Connelly C. S., Wurm H. and Kream R. M. (1994) Dextromethorphan inhibits ischemia-induced c-fos expression and delayed neuronal death in hippocampal neurons. Anesthesiology 81, 470-477.
15. Brog J. S., Salyapongse Z., Deutsch A. Y. and Zahm D. S. (1993) The patterns of afferent innervation of the core and shell in the "accumbens" part of the ventral striatum: immunohistochemical detection of retrogradely transported FluoroGold. J. comp. Neurol 338, 255-278.
16. 1B receptors in the rat. Hippocampus 5, 198-208.
17. Chesselet M. F., Gonzales C., Lin C. S., Polsky K. and Jin B. K. (1990) Ischemic damage in the striatum of adult gerbils: relative sparing of somatostatinergic and cholinergic interneurons contrasts with loss of efferent neurons. Expl Neurol. 110, 209-218.
18. Cools A. R., van den Bercken H. L., Horsting M. W. I., van Spaendonck K. P. M. and Berger H. J. C. (1984) Cognitive and motor shifting aptitude in Parkinson's disease. J. Neurol. Neurosurg. Psychiat. 47, 443-453.
19. Cummings J. L., Tomiyasu S., Read S. and Benson D. F. (1984) Amnesia with hippocampal lesions after cardiopulmonary arrest. Neurology 34, 679-681.
20. Divac I., Markowitsch H. J. and Pritzel M. (1978) Behavioral and anatomical consequences of small intrastriatal injections of kainic acid in the rat brain. Brain Res. 151, 523-532.
21. Gerhardt S. C. and Boast C. A. (1988) Motor activity changes following cerebral ischemia in gerbils are correlated with the degree of neuronal degeneration in hippocampus. Behav. Neurosci. 102, 301-303.
22. Gotti B., Benavides J., MacKenzie E. T. and Scatton B. (1990) The pharmacotherapy of focal cortical ischemia in the mouse. Brain Res. 522, 290-307.
23. Green E. J., Pazos A. J., Dietrich W. D., McGabe P. M., Schneidermann N., Lin B., Busto R., Globus M. Y.-T. and Ginsberg M. D. (1995) Combined postischemic hypothermia and delayed MK-801 treatment attenuates neurobehavioral deficits associated with transient global ischemia in rats. Brain Res. 702, 145-152.
24. Hagan J. J. and Beaughard M. (1990) The effects of forebrain ischaemia on spatial learning. Behav. Brain Res. 41, 151-160.
25. Hall E. D., Pazara K. E. and Braughler J. M. (1988) 21-Aminosteroid lipid peroxidation inhibitor U74006F protects against cerebral ischemia in gerbils. Stroke 19, 997-1002.
26. Hara H. and Kogure K. (1990) Prevention of hippocampus neuronal damage in ischemic gerbils by a novel lipid peroxidation inhibitor (quinazoline derivative). J. Pharmac. exp. Ther. 255, 906-913.
27. Heim C., Schwarz M., Klockgether T., Jaspers R., Cools A. R. and Sontag K.-H. (1986) GABAergic neurotransmission within the reticular part of the substantia nigra (SNR): role for switching motor patterns and performance of movements. Expl Brain Res. 63, 375-381.
28. Hodges H., Sowinski P., Fleming P., Kershaw T. R., Sinden J. D., Meldrum B. S. and Gray J. A. (1996) Contrasting effects of fetal CA1 and CA3 hippocampal grafts on deficits in spatial learning and working memory induced by global cerebral ischemia in rats. Neuroscience 72, 959-988.
29. Jaspers R. M. A., Block F., Heim C. and Sontag K.-H. (1990) Spatial learning is affected by transient occlusion of common carotid arteries (2VO): comparison of behavioural and histopathological changes after "2VO" and "four-vessel-occlusion" in rats. Neurosci. Lett. 117, 149-153.
30. Jaspers R., Schwarz M., Sontag K.-H. and Cools A. (1984) Caudate nucleus and programming behaviour in cats: role of dopamine in switching motor pattern. Behav. Brain Res. 14, 17-28.
31. Johnson P. I. and Stellar J. R. (1994) N-methyl-D-aspartic acid-induced lesions of the nucleus accumbens and/or ventral pallidum fail to attenuate lateral hypothalamic self-stimulation reward. Brain Res. 646, 73-84.
32. Josiassen R. C., Curry L. M. and Mancall E. L. (1983) Development of neuropsychological deficits in Huntington's disease. Archs Neurol. 40, 791-796.
33. Karasawa Y., Araki H. and Otomo S. (1994) Changes in locomotor activity and passive avoidance task performance induced by cerebral ischemia in Mongolian gerbils. Stroke 25, 645-650.
34. Kelly A. E. and Domesik V. B. (1982) The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: an anterograde and retrograde horseradish peroxidase study. Neuroscience 10, 2321-2335.
35. Kirino T. (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239, 57-69.
36. Kozuka M., Kobayashi K. and Iwata N. (1993) Changes in glucose utilization in the rat brain after transient forebrain ischemia. Stroke 24, 1568-1575.
37. Kretschmer B. and Schmidt W. (1996) Behavioural effects mediated by the modulatory site of the NMDA receptor in the anterodorsal striatum and nucleus accumbens. J. Neurosci. 16, 1561-1569.
38. Kuribayashi Y., Naritomi H., Sasaki M. and Sawada T. (1994) Effects of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran- 6yl-hydrogen phosphate] potassium salt on cerebral energy state and consciousness recovery following transient forebrain ischemia in gerbils. Arzneimittel-Forsch. 44, 995-998.
39. Kuroiwa T., Bonnekoh P. and Hossmann K.-A. (1991) Locomotor hyperactivity and hippocampal CA1 injury after transient forebrain ischemia of gerbils. Neurosci. Lett. 122, 141-144.
40. Lange K. W., Sahakian B. J., Quinn N. P., Marsden C. D. and Robbins T. W. (1995) Comparison of executive and visuospatial memory function in Huntington's disease and dementia of Alzheimer type matched for degree of dementia. J. Neurol. Neurosurg. Psychiat. 58, 598-606.
41. Lavoie A. M. and Mizumori S. J. (1994) Spatial, movement- and reward-sensitive discharge by medial ventral striatum neurons in rats. Brain Res. 638, 157-168.
42. Li H. and Buchan A. M. (1993) Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury. J. cerebr. Blood Flow Metab. 13, 933-939.
43. McNaughton B. L., Barnes C. A., Rao G., Baldwin J. and Rassmussen M. (1986) Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information. J. Neurosci. 6, 536-571.
44. Mizumori S. J., McNaughton B. L., Barnes C. A. and Fox K. B. (1989) Preserved spatial coding in hippocampal CA1 pyramidal cells during reversible suppression of CA3c output: evidence for pattern completion in hippocampus. J. Neurosci. 9, 3915-3928.
45. Moreau J. L., Pieri L. and Prud'hon B. (1989) Convulsions induced by centrally administered NMDA in mice: effects of NMDA antagonists, benzodiazepines, minor tranquilizers and anticonvulsants. Br. J. Pharmac. 98, 1050-1054.
46. Morris R. G. M., Anderson E., Lynch G. S. and Baudry M. (1986) Selective blockade of learning and blockade of long-term potentiation by an N-methyl-D-aspartate antagonist, AP5. Nature 319, 774-776.
47. Morris R. G. M., Garrud P., Rawlins J. N. P. and O'Keefe J. (1982) Place navigation impaired in rats with hippocampal lesions. Nature 297, 681-683.
48. Moser E., Moser M.-B. and Andersen P. (1993) Spatial learning impairment parallels the magnitude of dorsal hippocampal lesions, but is hardly present following ventral lesions. J. Neurosci. 13, 3916-3925.
49. Mossakowski M. J. and Gadamski R. (1990) Nimodipine prevents delayed neuronal death of sector CA1 pyramidal cells in short-term forebrain ischemia in Mongolian gerbils. Stroke 21 suppl. IV, 120-122.
50. 2 antagonist, markedly reduces infarct size following middle cerebral artery occlusion in the rat. Neurology 38, 1667-1673.
51. Nelson A., Lebessi A., Sowinski P. and Hodges H. (1997) Comparison of effects of global ischemia on spatial learning in the standard and radial water maze: Relationship of hippocampal damage to performance. Behav. Brain Res. 85, 93-116.
52. Nunn J. A. and Jarrad L. E. (1994) Silver impregnation reveals neuronal damage in cingulate cortex following 4VO ischaemia in the rat. NeuroReport 5, 2363-2366.
53. Nunn J. A., LePeillet E., Netto C. A., Hodges H., Gray J. A. and Meldrum B. S. (1994) Global ischemia: hippocampal pathology and spatial deficits in the water maze. Behav. Brain Res. 62, 41-54.
54. Olsen G. M., Scheel-Krüger J., Moller A. and Jensen L. H. (1994) Relation of spatial learning of rats in the Morris water maze task to the number of viable CA1 neurons following four-vessel occlusion. Behav. Neurosci. 108, 681-690.
55. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates. Academic, Sydney.
56. Pellegrini-Giampetro D. E., Zukin R. S., Bennett M. V. L., Cho S. and Pulsinelli W. A. (1992) Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats. Proc. natn. Acad. Sci. U.S.A. 89, 10,499-10,503.
57. Petito C. K., Feldmann E., Pulsinelli W. A. and Plum F. (1987) Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology 37, 1281-1286.
58. Pulsinelli W. A., Brierley J. B. and Plum F. (1982) Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol. 11, 491-498.
59. van Rijen P. C., Verheul H. B., van Echteld C. J., Balazs R., Lewis P., Nasim M. M. and Tulleken C. A. (1991) Effects of dextromethorphan on rat brain during ischemia and reperfusion assessed by magnetic resonance spectroscopy. Stroke 22, 343-350.
60. Robbins T. W., James M., Owen A. M., Lange K. W., Lees A. J., Leigh P. N., Marsden C. D., Quinn N. P. and Summers B. A. (1994) Cognitive deficits in progressive nuclear palsy, Parkinson's disease, and multiple system atrophy in tests sensitive to frontal lobe dysfunction. J. Neurol. Neurosurg. Psychiat. 57, 79-88.
61. Schmidt-Kastner R. and Freund T. F. (1991) Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 40, 599-636.
62. Siesjö B. K. (1990) Calcium in the brain under physiological and pathophysiological conditions. Eur. Neurol. 30 Suppl. 2, 3-9.
63. Siesjö B. K., Agadh C. D. and Bengtsson F. (1989) Free radicals and brain damage. Brain metab. Rev. 1, 165-211.
64. Sutherland R. J., Wishaw I. Q. and Kolb B. (1988) Contributions of cingulate cortex to two forms of spatial learning and memory. J. Neurosci. 8, 1863-1872.
65. Svensson A., Carlsson M. and Carlsson A. (1995) Crucial role of the accumbens nucleus in the neutrotransmitter interactions regulating motor control in mice. J. neural Transm. 101, 127-148.
66. Swan J. H. and Meldrum B. S. (1990) Protection by NMDA antagonists against selective cell loss following transient ischemia. J. cerebr. Blood Flow Metab. 10, 343-351.
67. Szabo L. (1989) (S)-emopamil, a novel calcium and serotonin antagonist for the treatment of cerebrovascular disorders. Arzneimittel-Forsch. 39, 309-314.
68. Szabo L. and Hofmann H. P. (1989) (S)-emopamil, a novel calcium and serotonin antagonist for the treatment of cerebrovascular disorders. Arzneimittel-Forsch. 39, 314-319.
69. Tanaka K., Gotoh F., Gomi S., Takashima S. and Mihara B. (1991) Autoradiographic analysis on second-messenger systems and local cerebral blood flow in ischemic gerbil brain. J. cerebr. Blood Flow Metab. 11, 283-291.
70. Valle F. P. (1970) Effects of strain, sex, and illumination on open-field behavior of rats. Am. J. Physiol. 83, 103-107.
71. Victor M. and Agamanolis D. (1990) Amnesia due to lesions confined to the hippocampus: a clinical-pathological study. J. cognit. Neurosci. 2, 246-257.
72. Wadenberg M. L., Ericson E., Marnusson O. and Ahlenius S. (1990) Suppression of conditioned avoidance behavior by the local application of (-)sulpiride into the ventral, but not the dorsal striatum of the rat. Biol. Psychiat. 28, 297-307.
73. Warner M. A., Neill K. H., Nadler J. V. and Crain B. J. (1991) Regionally selective effects of NMDA receptor antagonists against ischemic brain damage in the gerbil. J. cerebr. Blood Flow Metab. 11, 600-610.
74. Wiard R. P., Dickerson M. C., Beek O., Norton R. and Cooper B. R. (1995) Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia. Stroke 26, 466-472.
75. Wishaw I. Q., Mittelmann G., Bunch S. T. and Dunnett S. B. (1987) Impairments in the acquisition, retention and selection of spatial navigation strategies after medial caudate-putamen lesions in rats. Behav. Brain Res. 24, 125-138.
76. Wright J. W., Clemens J. A., Panetta J. A., Smalstig E. B., Weatherly L. S., Kramar E. A., Pederson E. S., Mungall B. H. and Harding J. W. (1996) Effects of LY231617 and angiotensin IV on ischemia-induced deficits in circular water maze and passive avoidance performance in rats. Brain Res. 717, 1-11.
77. Zola-Morgan S. and Squire L. R. (1986) Memory impairment in monkeys following lesions limited to the hippocampus. Behav. Neurosci. 100, 155-160.
78. Zola-Morgan S., Squire L. R. and Amaral D. G. (1986) Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus. J. Neurosci. 6, 2950-2967.