Mosaic analyses reveal the function of Drosophila Ras in embryonic dorsoventral patterning and dorsal follicle cell morphogenesis

Development

Volumn 129, Issue 9, 2002, Pages 2209-2222

  James, Karen E ^a   Dorman, Jennie B ^a   Berg, Celeste A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cell migration; Dorsal ventral polarity; Drosophila melanogaster; E cadherin; Egfr; Epithelial morphogenesis; Follicle cell; Oogenesis; pipe; Ras

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; RAS PROTEIN; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; CELL CLONING; CELL MIGRATION; CELL POPULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EGG SHELL; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; EMBRYO POLARITY; EPITHELIUM; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; HOMOZYGOSITY; MORPHOGENESIS; MOSAICISM; NONHUMAN; NULL ALLELE; OOCYTE DEVELOPMENT; OVARY FOLLICLE CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; RESPIRATORY SYSTEM; REVIEW; SIGNAL TRANSDUCTION; SOMATIC CELL;

ANIMALS; BODY PATTERNING; CADHERINS; CELL MOVEMENT; CELL SIZE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENES, ERBB-1; GENES, INSECT; GENES, RAS; MODELS, BIOLOGICAL; MOSAICISM; MUTATION; OOGENESIS; OVARIAN FOLLICLE; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SULFOTRANSFERASES;

ANIMALIA; ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; MELANOGASTER;

EID: 0036340036     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (60)

1. Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cells
2. Pinning down positional information: Dorsal-ventral polarity in the Drosophila embryo
3. sog and dpp exert opposing maternal functions to modify toll signaling and pattern the dorsoventral axis of the Drosophila embryo
4. Ras and Rho GTPases: A family reunion
5. Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis
6. Increasing complexity of Ras signaling
7. Molecular analysis of the Drosophila EGF receptor homolog reveals that several genetically defined classes of alleles cluster in subdomains of the receptor protein
8. Coordinately and differentially mutable activities of torpedo, the Drosophila melanogaster homolog of the vertebrate EGF receptor gene
9. Two signalling pathways specify localised expression of the Broad-Complex in Drosophila eggshell patterning and morphogenesis
10. Top-DER- and Dpp-dependent requirements for the Drosophila fos/kayak gene in follicular epithelium morphogenesis
11. Autoproteolysis and feedback in a protease cascade directing Drosophila dorsal-ventral cell fate
12. The Drosophila bunched gene is a homologue of the growth factor stimulated mammalian TSC-22 sequence and is required during oogenesis
13. Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis
14. Conservation of dorsal-ventral patterning in arthropods and chordates
15. Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein
16. The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis
17. Drosophila oocyte localization is mediated by differential cadherin-based adhesion
18. SRC64 regulates the localization of a Tec-family kinase required for Drosophila ring canal growth
19. A novel Drosophila serpin that inhibits serine proteases
20. The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway
21. A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases
22. Soma-to-germline interactions during Drosophila oogenesis are influenced by dose-sensitive interactions between cut and the genes cappuccino, ovarian tumor and agnostic
23. E-cadherin relates to EGFR expression and lymph node metastasis in primary breast carcinoma
24. The homeobox gene mirror links EGF signalling to embryonic dorso-ventral axis formation through notch activation
25. Two distinct roles for Ras in a developmentally regulated cell migration
26. Germline stem cell division and egg chamber development in transplanted Drosophila germaria
27. Drosophila Src42A is a negative regulator of RTK signaling
28. A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction
29. Identification and behavior of epithelial stem cells in the Drosophila ovary
30. Spatzle regulates the shape of the Dorsal gradient in the Drosophila embryo
31. DE-Cadherin is required for intercellular motility during Drosophila oogenesis
32. Localized requirements for windbeutel and pipe reveal a dorsoventral prepattern within the follicular epithelium of the Drosophila ovary
33. EGF receptor signaling in Drosophila oogenesis
34. A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion
35. D-cbl, a negative regulator of the Egfr pathway, is required for dorsoventral patterning in Drosophila oogenesis
36. Local Gurken signaling and dynamic MAPK activation during Drosophila oogenesis
37. Combined activities of Gurken and decapentaplegic specify dorsal chorion structures of the Drosophila egg
38. Domain requirements for the Dock adapter protein in growth-cone signaling
39. Sprouty is a general inhibitor of receptor tyrosine kinase signaling
40. The relationship between ovarian and embryonic dorsoventral patterning in Drosophila
41. Binuclear Drosophila oocytes: Consequences and implications for dorsal-ventral patterning in oogenesis and embryogenesis
42. A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo
43. The Tec29 tyrosine kinase is required during Drosophila embryogenesis and interacts with Src64 in ring canal development
44. Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis
45. Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo
46. Cell signaling by receptor tyrosine kinases
47. Differential activity of Ras 1 during patterning of the Drosophila dorsoventral axis
48. Ras 1 interacts with multiple new signaling and cytoskeletal loci in drosophila eggshell patterning and morphogenesis
49. Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster
50. A thousand and one roles for the Drosophila EGF receptor
51. Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe
52. Spatially restricted expression of pipe in the Drosophila egg chamber defines embryonic dorsal-ventral polarity
53. Invertebrate phosphatidylinositol-specific phospholipases C and their role in cell signaling
54. Genetic analysis of cadherin function in animal morphogenesis
55. Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos
56. Versatility in signalling: Multiple responses to EGF receptor activation during Drosophila oogeflesis
57. The Ras signaling pathway in Drosophila
58. An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg
59. Analysis of genetic mosaics in developing and adult Drosophila tissues