Axon specification in hippocampal neurons

Neuroscience Research

Volumn 43, Issue 4, 2002, Pages 305-315

  Fukata, Yuko ^a   Kimura, Toshihide ^a   Kaibuchi, Kozo ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Axon; CRMP 2; Dendrite; Neuronal polarity; Rho family GTPases

Indexed keywords

GUANOSINE TRIPHOSPHATASE;

CYTOSKELETON; DENDRITE; HIPPOCAMPUS; MOLECULAR MECHANICS; NERVE CELL; NERVE FIBER; NEURITE; NEUROSCIENCE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; REVIEW;

ANIMALS; AXONS; CELL POLARITY; CELLS, CULTURED; HIPPOCAMPUS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NERVE TISSUE PROTEINS; NEURONS; RHO GTP-BINDING PROTEINS;

EID: 0036312353     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(02)00062-7     Document Type: Review

References (79)

1. CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae
2. Rho proteins: Targets for bacterial toxins
3. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
4. Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase
5. Axon formation: A molecular model for the generation of neuronal polarity
6. Phosphorylation of collapsin response mediator protein-2 by rho-kinase. Evidence for two separate signaling pathways for growth cone collapse
7. Identification of 3′UTR region implicated in tau mRNA stabilization in neuronal cells
8. Microtubules and axonal growth
9. The role of motor proteins in establishing the microtubule arrays of axons and dendrites
10. Essential role of neural Wiskott-Aldrich syndrome protein in neurite extension in PC12 cells and rat hippocampal primary culture cells
11. The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)-insulin-like growth factor-1, and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture
12. Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules
13. Catastrophic revelations about Op18/stathmin
14. A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons
15. Neuronal polarity: Vectorial cytoplasmic flow precedes axon formation
16. The role of local actin instability in axon formation
17. Differentiated neurons retain the capacity to generate axons from dendrites
18. Establishment of neuronal polarity: Lessons from cultured hippocampal neurons [In Process Citation]
19. Newly assembled microtubules are concentrated in the proximal and distal regions of growing axons
20. Composite microtubules of the axon: Quantitative analysis of tyrosinated and acetylated tubulin along individual axonal microtubules
21. The role of selective transport in neuronal protein sorting
22. Neuronal polarity
23. The distribution of glutamate receptors in cultured rat hippocampal neurons: Postsynaptic clustering of AMPA-selective subunits
24. Experimentally induced alteration in the polarity of developing neurons
25. The establishment of polarity by hippocampal neurons in culture
26. Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau
27. Local presentation of substrate molecules directs axon specification by cultured hippocampal neurons
28. Differential effects of NgCAM and N-cadherin on the development of axons and dendrites by cultured hippocampal neurons
29. The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture
30. Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone
31. Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
32. CRMP-2 binds to tubulin heterodimers to promote microtubule assembly: A possible mechanism for CRMP-2-mediated axonal growth
33. Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33
34. Experimental observations on the development of polarity by hippocampal neurons in culture
35. The role of cytoskeleton in organizing growth cones: A microfilament-associated growth cone component depends upon microtubules for its localization
36. Rho GTPases and the actin cytoskeleton
37. Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes
38. Mechanisms of neuronal polarity
39. Microtubule organization and dynamics dependent on microtubule-associated proteins
40. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells
41. Cytoskeleton: Microtubules get the signal
42. CRMP-2 induces axons in cultured hippocampal neurons
43. Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1
44. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
45. Inhibition of axonal growth by brefeldin A in hippocampal neurons in culture
46. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
47. P160 RhoA-binding kinase ROKalpha induces neurite retraction
48. Expression patterns of GABAA receptor subtypes in developing hippocampal neurons
49. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
50. Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia
51. The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
52. Rho family GTPases and neuronal growth cone remodelling: Relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
53. Evidence for the involvement of Tiam1 in axon formation
54. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; Opposing roles for the small GTPases Rac and Rho
55. Semaphorin-mediated axonal guidance via Rho-related G proteins
56. Rho GTPases in neuronal morphogenesis
57. Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
58. Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines
59. Establishment and plasticity of neuronal polarity
60. Induction of filopodium formation by a WASP-related actin- depolymerizing protein N-WASP
61. ADP-ribosylation of the rho/rac proteins induces growth inhibition, neurite outgrowth and acetylcholine esterase in cultured PC-12 cells
62. Regulation and function of the Rho subfamily of small GTPases
63. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
64. MDia mediates Rho-regulated formation and orientation of stable microtubules
65. Semaphorin 3A is a chemoattractant for cortical apical dendrites
66. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
67. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
68. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
69. Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
70. Does motor protein intelligence contribute to neuronal polarity?
71. EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin
72. Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture
73. Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes
74. Making the connection: Cytoskeletal rearrangements during growth cone guidance
75. Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF
76. Rho GTPases and signaling networks
77. NILE/L1 and NCAM-polysialic acid expression on growing axons of isolated neurons
78. Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
79. Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity