A new technique to co-localise membrane proteins with Homer/vesl

Biochemical and Biophysical Research Communications

Volumn 295, Issue 3, 2002, Pages 756-765

  Hiroaki, Yoko ^a   Nishikawa, Kouki ^a   Mitsuoka, Kaoru ^a   Tachibana, Taro ^b   Sobue, Kenji ^b   Doi, Tomoko ^a   Fujiyoshi, Yoshinori ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c Japan Biological Information Research Center   (Japan)

Author keywords

2D crystallisation; Co expression; Electron crystallography; Endothelin B receptor; G protein coupled receptors; Homer 1c; Localisation; Metabotropic glutamate receptor; Postsynapse; Proline rich

Indexed keywords

ENDOTHELIN B RECEPTOR; G PROTEIN COUPLED RECEPTOR; MEMBRANE PROTEIN; METABOTROPIC RECEPTOR; PROLINE; PROTEIN; PROTEIN HOMER VESL; PROTEIN PSD ZIP45; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; SYNAPTIC MEMBRANE; TECHNIQUE;

ANIMALS; BIOCHEMISTRY; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; COS CELLS; CRYSTALLOGRAPHY, X-RAY; DETERGENTS; DNA, COMPLEMENTARY; HUMANS; INSECTS; MICELLES; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; NEUROPEPTIDES; POINT MUTATION; PROLINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RATS; SIGNAL TRANSDUCTION;

EID: 0036310707     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00738-6     Document Type: Article

References (28)

1. Homer: A link between neural activity and glutamate receptor function
2. Crystal structure of rhodopsin: A G protein-coupled receptor
3. Structural determinants of water permeation through aquaporin-1
4. Glutamate receptors: Brain function and signal transduction
5. Cryptic dimer interface and domain organization of the extracellular region of metabotropic glutamate receptor subtype 1
6. Homer: A protein that selectively binds metabotropic glutamate receptors
7. Vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesis
8. Isolation of PSD-Zip45, a novel Homer/vesl family protein cintaining leucine zipper motifs, from rat brain
9. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of Homer-related, synaptic proteins
10. Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors
11. Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors
12. Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin
13. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins
14. Co-expression of metabotropic glutamate receptor type 1α with Homer-1a/Vesl-1S increases the cell surface expression of the receptor
15. Homer 1b regulates the trafficking of group I metabotropic glutamate receptors
16. Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1α: Evidence for an anchoring function
17. Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by Homer1 proteins and neuronal excitation
18. The scaffold protein, Homer1b/c, regulates axon pathfinding in the central nervous system in vivo
19. Regulation of dendritic spine morphology and synaptic function by Shank and Homer
20. Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition
21. Structure of the Enabled/VASP homology 1 domain-peptide complex: A key component in the spatial control of actin assembly
22. Ligand recognition by SH3 and WW domains: The role of N-alkylation in PPII helices
23. Involvement of unique leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering
24. Characterization of human endothelin B receptor and mutant receptors expressed in insect cells
25. Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity
26. The N-terminal domain of Homer/Vesl is a new class II EVH1 domain
27. Crystal structure of Homer 1 family conserved region reveals the interaction between EVH1 domain and own proline-rich motif
28. The pleckstrin domains of dynamin isoforms require oligomerization for high affinity phosphoinositide binding