Expression of the interleukin-2 receptor α (CD25) is selectively decreased on decidual CD4 + and CD8 + T lymphocytes in normal pregnancies

Molecular Human Reproduction

Volumn 8, Issue 7, 2002, Pages 667-673

  Chao, Kunag Han ^a   Wu, Ming Yih ^a   Yang, Jehn Hsiahn ^a   Chen, Shee Uan ^a   Yang, Yu Shih ^a   Ho, Hong Nerng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

CD25; CD69; Decidua; HLA DR; T lymphocytes

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 2 RECEPTOR;

ADULT; ALLOGRAFT; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DECIDUA; DOWN REGULATION; ENDOMETRIUM; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; KARYOTYPING; LUTEAL PHASE; LYMPHOCYTE FUNCTION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ADULT; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHROMOSOME ABERRATIONS; DECIDUA; ENDOMETRIUM; FEMALE; HUMANS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; PREGNANCY; RECEPTORS, INTERLEUKIN;

EID: 0036309539     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation
2. Peripheral tolerance of an allograft in adult rats-characterization by low interleukin-2 and interferon-gamma mRNA levels and by strong accumulation of major histocompatibility complex transcripts in the graft
3. A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
4. Prevention of acute rejection episodes with an anti-interleukin 2 receptor monoclonal antibody. I. Results after combined pancreas and kidney transplantation
5. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor
6. Immune suppression and Th1/Th2 balance in pregnancy revisited: A (very) personal tribute to Tom Wegmann
7. Controversies in reproductive immunology
8. Hard science versus phenomenology in reproductive immunology
9. Active suppression of host-vs-graft reaction in pregnant mice. VI. Soluble suppressor activity obtained from decidua of allopregnant mice blocks the response to IL 2
10. Why did your mother reject you? Immunogenetic determinants of the response to environmental selective pressure expressed at the uterine level
11. Fgl2 prothrombinase expression in mouse trophoblast and decidua triggers abortion but may be countered by OX-2
12. Procoagulants in fetus rejection: The role of the OX-2 (CD200) tolerance signal
13. Lack of IL-2 cytokine expression despite IL-2 messenger RNA transcription in tumor-infiltrating lymphocytes in primary human breast carcinoma: Selective expression of early activation markers
14. Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway
15. Immunosuppressor factor(s) produced by decidua-associated suppressor cells: A proposed mechanism for fetal allograft survival
16. Cell populations in the human early pregnancy decidua: Natural killer activity and response to interleukin-2 of CD56-positive large granular lymphocytes
17. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15
18. Suppression of lymphocyte reactivity in vitro by a soluble factor secreted by explants of human decidua
19. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor
20. Activation status of T and NK cells in the endometrium throughout menstrual cycle and normal and abnormal early pregnancy
21. Distribution of Th1 and Th2 cell populations in human peripheral and decidual T cells from normal and anembryonic pregnancies
22. Screening for cytokine messenger ribonucleic acids in purified human decidual lymphocyte populations by the reverse-transcriptase polymerase chain reaction
23. Cytokine production and cytokine receptor expression by cells of the human first trimester placental-uterine interface
24. Graft-infiltrating T helper cells, CD45RC phenotype and Th1/Th2-related cytokines in donor-specific transfusion-induced tolerance in adult rats
25. Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex
26. Human trophoblast and JEG choriocarcinoma cells are sensitive to lysis by IL-2-stimulated decidual NK cells
27. Screening for cytokine mRNA in human villous and extravillous trophoblasts using the reverse-transcriptase polymerase chain reaction (RT-PCR)
28. IL-15 expression at human endometrium and decidua
29. A randomized, placebo-controlled trial with anti-interleukin-2 receptor antibody for immunosuppressive induction therapy after liver transplantation
30. Molecular cloning and expression of cDNAs for the human interleukin-2 receptor
31. Profile of cytokine mRNA expression in peri-implantation human endometrium
32. Expression of interleukin-15 in human endometrium and decidua
33. Proliferative activity in endometrial stromal granulocytes throughout menstrual cycle and early pregnancy
34. The effect of interleukin 2 and transforming growth factor-beta 2 (TGF-beta 2) on the proliferation and natural killer activity of decidual CD16-CD56 bright natural killer cells
35. Cytokine production by CD16-CD56 bright natural killer cells in the human early pregnancy decidua
36. Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions
37. Down-regulation of CD25 expression on the surface of activated tumor-infiltrating lymphocytes in human cervical carcinoma
38. A novel role of metalloproteinase in cancer-mediated immunosuppression
39. Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer
40. Interleukin-2: Inception, impact and implications
41. Proliferative activity of lymphoid cells in human endometrium throughout the menstrual cycle
42. Evidence of T-cell activation and potential cytokine action in human endometrium
43. Cloning of the gamma chain of the human IL-2 receptor
44. The IL-2/IL-2 receptor system: A current overview
45. T cell activation via Leu-23 (CD69)
46. Demonstration of a non-Tac peptide that binds interleukin 2: A potential participant in a multichain interleukin 2 receptor complex
47. A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. II. Expression of Tac antigen on activated cytotoxic killer T cells, suppressor cells and on one of two types of helper T cells
48. Peripheral blood monitoring during and after rejection-prophylaxis with a monoclonal anti-interleukin-2-receptor antibody in kidney and heart transplant recipients
49. Immunosuppressive properties of murine trophoblast
50. Induction of transient murine T cell anergy by a low molecular weight compound obtained from supernatants of human placental cultures is linked to defective phosphorylation of TCR CD3 chain
51. The structure, function and expression of interleukin-2 receptors on normal and malignant lymphocytes
52. The interleukin-2 receptor
53. Suppression of lymphocyte reactivity in vitro by supernatants of explants of human endometrium
54. Placental immunotrophism: Maternal T cells enhance placental growth and function