Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium

Toxicological Sciences

Volumn 67, Issue 2, 2002, Pages 207-218

  Wade, Michael G ^a,e   Parent, Sophie ^a   Finnson, Kenneth W ^b   Foster, Warren ^c   Younglai, Edward ^c   McMahon, Avril ^a   Cyr, Daniel G ^b   Hughes, Claude ^d  

^a HEALTH CANADA   (Canada)

^b INRS INSTITUT ARMAND FRAPPIER   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e Environmental Health Centre Ottawa   (Canada)

Author keywords

Dioxin; Organochlorines; Outer ring deiodinase; PCB; Thyroid; Thyroxine; UDP glucuronyltransferase

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALDRIN; BENZENE DERIVATIVE; CADMIUM; CHLORPHENOTANE; DIELDRIN; ENDOSULFAN; GLUCURONOSYLTRANSFERASE; HEPTACHLOR; HEXACHLOROBENZENE; HEXACHLOROCYCLOHEXANE; LEAD; LIOTHYRONINE; METHOXYCHLOR; MIREX; ORGANOCHLORINE DERIVATIVE; POLYCHLORINATED BIPHENYL; THYROID HORMONE; THYROTROPIN; THYROXINE; THYROXINE DEIODINASE;

AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FOOD CONTAMINATION; HISTOLOGY; HORMONE TRANSPORT; HYPOTHALAMUS HYPOPHYSIS THYROID SYSTEM; LIOTHYRONINE BLOOD LEVEL; LIVER METABOLISM; LONG TERM EXPOSURE; MALE; MORPHOLOGY; NONHUMAN; RAT; RISK ASSESSMENT; SEXUAL MATURITY; THYROID FOLLICLE; THYROID FUNCTION; THYROID GLAND; THYROID HORMONE METABOLISM; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TOXICITY TESTING; WATER CONTAMINATION;

ANIMALS; CADMIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENVIRONMENTAL POLLUTANTS; GLUCURONOSYLTRANSFERASE; HORMONE ANTAGONISTS; HYDROCARBONS, CHLORINATED; INSECTICIDES; LEAD; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; THYROID GLAND; THYROID HORMONES; TOXICITY TESTS;

ANIMALIA;

EID: 0036307676     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/67.2.207     Document Type: Article

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