Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus

Synapse

Volumn 45, Issue 2, 2002, Pages 143-151

  Alves, Stephen E ^a,b   Hoskin, Elena ^b   Lee, Susan J ^b   Brake, Wayne G ^b   Ferguson, Deveroux ^c   Luine, Victoria ^c   Allen, Patrick B ^b   Greengard, Paul ^b   McEwen, Bruce S ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Dendritic spines; Estradiol; Norepinephrine; Plasticity; Progesterone

Indexed keywords

BRAIN MONOAMINE; BRAIN PROTEIN; ESTRADIOL BENZOATE; FENCLONINE; NORADRENALIN; PROGESTERONE; PROTEIN SPINOPHILIN; SEROTONIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC SPINE; DORSAL RAPHE NUCLEUS; FEMALE; GOLGI COMPLEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HORMONAL REGULATION; NERVE CELL PLASTICITY; NONHUMAN; NORADRENALIN BRAIN LEVEL; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PYRAMIDAL NERVE CELL; RADIOIMMUNOASSAY; RAT; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; SYNAPTOGENESIS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTRADIOL; FEMALE; HIPPOCAMPUS; HISTOLOGICAL TECHNIQUES; IMMUNOHISTOCHEMISTRY; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; PROGESTERONE; RADIOIMMUNODETECTION; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

EID: 0036303199     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.10093     Document Type: Article

References (66)

1. Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
2. Estrogen-regulated progestin receptors are found in the midbrain raphe but not hippocampus of estrogen receptor alpha (ERα) gene-disrupted mice
3. The serotonin-producing neurons of the midbrain median and dorsal raphe nuclei
4. Serotonin neurons, neuroplasticity, and homeostasis of neural tissue
5. 1A agonist and dexamtheasone reversal of parachloroamphetamine induced loss of MAP-2 and synaptophysin immunoreactivity in adult rat brain
6. Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus
7. Functional consequences of central serotonin depletion produced by repeated fenfluramine administration in rats
8. Fluoxetine selectively alters 5-hydroxytryptaminelA and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells
9. Ovarian steroids and serotonin neural function
10. A rapid and sensitive method for the quantification of microgram quantities of protein using the principle of protein-dye binding
11. Novel target sites for estrogen action in the dorsal hippocampus: An examination of synaptic proteins
12. pCPA reduces both monoaminergic afferents and non-monoaminergic synapses in the cerebral cortex
13. Region of serotonin-mediated synaptic plasticity in the chicken spinal cord with development and aging
14. The stimulating influence of the raphe nuclei on the morphofunctional development of the hippocampus during their combined cultivation
15. Serotonergic facilitation of acetylcholine release in vivo from rat dorsal hippocampus via serotonin 5-HT3 receptors
16. Molecular psychiatry: Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity
17. Stress, antidepressant treatments, and neurtrophic factors: Molecular and cellular mechanisms
18. A molecular and cellular theory of depression
19. Dendritic spine changes associated with hippocampal long-term synaptic plasticity
20. Synaptogenesis in the postnatal rat fascia dentate is influenced by 5-HT1a receptor activation
21. Spinophilin regulates the formation and function of dendritic spines
22. Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
23. Transient reduction in hippocampal serotonergic innervation after neonatal parachloro-amphetamine treatment
24. Regulation of beta 1-adrenergic receptor mRNA and ligand binding by antidepressant treatments and norepinephrine depletion in rat frontal cortex
25. Chronic fluoxetine treatment upregulates 5-HT uptake sites and 5-HT2 receptors in the rat brain: An autoradiographic study
26. Structure and function of the brain serotonin system
27. Ontogeny of the serotonergic system in the rat: Serotonin as a developmental signal
28. Hormonal regulation of hippocampal spine synapse density involves subcortical mediation
29. Estrogen-induction of dendritic spines in ventromedial hypothalamus and hippocampus: Effects of neonatal aromatase blockade and adult GDX
30. Anti-psychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex
31. Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters
32. Serotonin and acetylcholine are crucial to maintain hippocampal synapses and memory acquisition in rats
33. Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficits in the adult rat: A possible model of neurodevelopmental disorders with cognitive deficits
34. Estrogen actions in the central nervous system
35. Inhibition of dendritic spine induction on hippocampal CA1 pyramidal neurons by a non-steroidal estrogen antagonist in female rats
36. Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation
37. Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites
38. Granule cells in aging rats are sexually dimorphic in their response to estradiol
39. Estradiol increases dendritic spine density by reducing GABA neurotransmission in hippocampal neurons
40. Regulation of synapse density by 5-HT2A receptor agonist and antagonist in the spinal cord of chicken embryo
41. Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine proliferation in hippocampus
42. Synaptic loss following removal of serotonergic fibers in newly hatched and adult chickens
43. Progestin receptor levels in rat hypothalamic and limbic nuclei
44. Estrogen-serotonin interactions: Implications for affective regulation
45. Estrogen regulates functional inhibition of hippocampal CA1 pyramidal cells in the adult female rat
46. Memory retention is modulated by acute estradiol and progesterone replacement
47. Evidence for novel estrogen binding sites in the rat hippocampus
48. Distribution of estrogen receptor β immunoreactivity in the rat central nervous system
49. Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system
50. Regulation of dendritic spine stability
51. Localization of estrogen receptor alpha (ERa) in pyramidal neurons of the developing rat hippocampus
52. Synaptic density of the prefrontal cortex regulated by dopamine instead of serotonin in rats
53. Effect of chronic restraint stress on dendritic spines and excrescences of hippocampal CA3 pyramidal neurons - A quantitative study
54. Early postnatal administration of 5,7-DHT: Effects on serotonergic neurons and terminals
55. Distribution and hormone regulation of estrogen receptor-immunoreactive cells in the hippocampus of male and female rats
56. Localization of 5-HT1A receptors to astroglial cells in adult rats: Implications for neuronal-glial interactions and psychoactive drug mechanism of action
57. Astroglial 5-HT1a receptors and S-100 beta in development and plasticity
58. Serotonin depletion in the adult rat causes loss of the dendritic marker MAP-2
59. Serotonin regulates synaptic connections in the dentate molecular layer of adult rats via 5-HT1a receptors: Evidence for a glial mechanism
60. Effects of estrogen in the CNS
61. Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat
62. Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor dependent mechanism
63. Estradiol increases the frequency of multiple synapse boutons in the hippocampal CA1 region of the adult female rat
64. Estrogen increases synaptic connectivity between single presynaptic inputs and multiple postsynaptic CA1 pyramidal cells: A serial electron-microscopic study
65. 3 receptor agonists attenuate glutamate-induced firing in rat hippocampal CA1 pyramidal cells