Analysis of chromosomal aberrations involving chromosome 1q31→q53 in a DMBA-induced rat fibrosarcoma cell line: Amplification and overexpression of Jak2

Cytogenetics and Cell Genetics

Volumn 95, Issue 3-4, 2002, Pages 202-209

  Sjöling, Åsa ^a   Lindholm, H ^b   Samuelson, E ^a   Yamasaki, Y ^c   Watanabe, T K ^c   Tanigami, A ^c   Levan, G ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF SKÖVDE   (Sweden)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAX GENE; CENTROMERE; CHROMOSOME 1Q; CHROMOSOME ABERRATION; CONTROLLED STUDY; FIBROSARCOMA; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE AMPLIFICATION; GENE MAPPING; GENE OVEREXPRESSION; JAK2 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; OMP GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; SOUTHERN BLOTTING;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; CARCINOGENS; CHROMOSOME ABERRATIONS; CHROMOSOME MAPPING; CORTACTIN; CYCLIN D1; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTORS; FIBROSARCOMA; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; IN SITU HYBRIDIZATION, FLUORESCENCE; JANUS KINASE 2; MICE; MICROFILAMENT PROTEINS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; RATS, INBRED BN; TUMOR CELLS, CULTURED;

EID: 0036281577     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Amplification of cyclin D1 in squamos cell carcinoma of the head and neck and the prognostic value of chromosomal abnormalities and cyclin D1 expression
2. Detailed map of a region commonly amplified at 11q13→q14 in human breast carcinoma
3. Genetic alterations in breast cancer
4. STATs in oncogenesis
5. The role of STATs in myeloid differentiation and leukemia
6. Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons
7. Endometrial carcinoma in BDII/Han rats: Model of a spontaneous hormone-dependent tumor
8. The multiple roles of PTEN in tumor suppression
9. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
10. Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat
11. Genome scan and congenic strains for blood pressure QTL using Dahl salt-sensitive rats
12. Chromosomal localization of the rat Harvey-ras-1 (HRAS) by in situ hybridization
13. Allelic imbalance in mammary carcinomas induced by either 7,12-dimethylbenz[a]anthracene or ionizing radiation in rats carrying genes conferring differential susceptibilities to mammary carcinogenesis
14. Amplification and overexpression of the hepatocyte growth factor receptor (HGFR/MET) in rat DMBA sarcomas
15. Cytogenetic localization of the growth and reproduction complex (Grc) in the rat and in the mouse and its position in relation to RT1.EC and other loci in the rat MHC
16. Cytogenetic changes in hepatocarcinomas from rats treated with chronic exposure to diethylnitrosamine
17. A new fixation procedure for improved quality G-bands in routine cytogenetic work
18. Detailed comparative gene map of rat chromosome 1 with mouse and human genomes and physical mapping of an evolutionary chromosomal breakpoint
19. Patterns of DNA amplification at band q13 of chromosome 11 in human breast cancer
20. Allele-specific losses of heterozygosity on chromosomes 1 and 17 revealed by whole genome scan of ethylnitrosourea-induced BDIX × BDIV hybrid rat gliomas
21. Ethylnitrosourea-induced development of malignant schwannomas in the rat: Two distinct loci on chromosome 10 involved in tumor susceptibility and oncogenesis
22. Chromosomal assignment of the Bcl2-related genes, Bcl2l and Bax, in the mouse and rat
23. A whole-genome radiation hybrid panel and framework map of the rat genome
24. The stability of broken ends of chromosomes in Zea mays
25. The chromosomes of primary 7,12-dimethylbenz(a)anthracene-induced rat sarcomas
26. Detection of chromosomal imbalances in leiomyosarcoma by comparative genomic hybridization and interphase cytogenetics
27. A genome scan localizes five non-MHC controlling collagen-induced arthritis in rats
28. Molecular cloning and sequencing of a cDNA for olfactory marker protein
29. The involvement of the chromosome 11q13 region in human malignancies: Cyclin D1 and EMS1 are two new candidate oncogenes - A review
30. Genetic identification of multiple loci that control breast cancer susceptibility in the rat
31. A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification
32. A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat
33. The rat gene map
34. Rat chromosome 1: Regional localization of seven genes (Slc9a3, Srd5a1, Esr, Tcp1, Grik5, Tnnt3, Jak2) and anchoring of the genetic linkage map to the cytogenetic map
35. Radiation hybrid map of the mouse genome
36. A dual-color FISH gene map of the proximal region of rat chromosome 4 and comparative analysis in human and mouse
37. Independent amplification of two gene clusters on chromosome 4 in rat endometrial cancer: Identification and molecular characterization
38. Genome-wide assessment of genetic alterations in DMBA-induced rat sarcomas: Cytogenetic, CGH and allelotype analyses reveal recurrent DNA copy number changes in rat chromosomes 1, 2, 4, and 7
39. A radiation hybrid map of the rat genome containing 5,255 markers
40. Construction and characterization of a 10-fold genome equivalent rat P1-derived artificial chromosome library
41. Mouse chromosome 19 and distal rat chromosome 1: A chromosome segment conserved in evolution
42. Rapid isolation and characterization of amplified DNA by chromosome microdissection: Identification of IGF1R amplification in malignant melanoma