Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits

Immunology

Volumn 106, Issue 2, 2002, Pages 182-189

  Antoniou, Antony N ^a   Ford, Stuart ^a   Pilley, Elizabeth S ^a   Blake, Neil ^b,c   Powis, Simon J ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; DIMER; HLA A2 ANTIGEN; HLA B ANTIGEN; HLA B15 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NUCLEOTIDE BINDING PROTEIN; POLYPEPTIDE; PROTEIN; PROTEIN SUBUNIT; PROTEIN TAP2; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; UNCLASSIFIED DRUG;

ALLELE; ANTIGEN PRESENTATION; ARTICLE; CELL LINE; CELL LYSATE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; VACCINIA VIRUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; HLA-A2 ANTIGEN; HLA-B ANTIGENS; HUMANS; MACROMOLECULAR SUBSTANCES; MOLECULAR CHAPERONES; RATS; TRANSFECTION;

EID: 0036278476     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2002.01415.x     Document Type: Article

References (39)

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3. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter
4. ABC transporters: From microorganisms to man
5. The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex
6. ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly
7. A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules
8. A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes
9. Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP
10. Substrate specificity of allelic variants of the TAP peptide transporter
11. Functional analysis by site-directed mutagenesis of the complex polymorphism in rat transporter associated with antigen processing
12. Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site
13. Identification of a contact region for peptide on the TAP1 chain of the transporter associated with antigen processing
14. Distinct functional properties of the TAP subunits coordinate the nucleotide-dependent transport cycle
15. Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules
16. Distinct functions and cooperative interaction of the subunits of the transporter associated with antigen processing (TAP)
17. Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation
18. Major histocompatibility complex class I molecules interact with both subunits of the transporter associated with antigen processing, TAP1 and TAP2
19. 3D-structure of transporter associated with antigen processing (TAP) obtained by single particle image analysis
20. Inhibition of antigen presentation by the glycine/alanine repeat domain is not conserved in simian homologues of Epstein-Barr virus nuclear antigen 1
21. Processing of a multiple membrane spanning Epstein-Barr virus protein for CD8(+) T cell recognition reveals a proteasome-dependent, transporter associated with antigen processing-independent pathway
22. Selection of recombinant vaccinia viruses on the basis of plaque formation
23. HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells
24. Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line, 220
25. Distinct differences in association of MHC class I with endoplasmic reticulum proteins in wild-type, and beta 2-microglobulin- and TAP-deficient cell lines
26. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry
27. The protease inhibitor, N-acetyl-1-leucyl-1-leucyl-leucyl-L-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum
28. Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains
29. Pairing of the nucleotide binding domains of the transporter associated with antigen processing
30. Herpes simplex virus inhibitor ICP47 destabilizes the transporter associated with antigen processing (TAP) heterodimer
31. How selective is the transporter associated with antigen processing?
32. Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi
33. The peptide-binding motif for the human transporter associated with antigen processing
34. Allosteric crosstalk between peptide-binding, transport, and ATP hydrolysis of the ABC transporter TAP
35. Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing
36. HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading
37. TAP-independent presentation of CTL epitopes by Trojan antigens
38. Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing
39. Structure of MsbA from E. coli: A homolog of the multidrug resistance ATP binding cassette (ABC) transporters