Identification of a contact region for peptide on the TAP1 chain of the transporter associated with antigen processing

Journal of Immunology

Volumn 156, Issue 6, 1996, Pages 2186-2195

  Nijenhuis, Marga ^a   Schmitt, Sabine ^a   Armandola, Elena A ^a   Obst, Reinhard ^a   Brunner, Josef ^b   Hämmerling, Günter J ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CROSS LINKING; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT;

AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ATP-BINDING CASSETTE TRANSPORTERS; B-LYMPHOCYTES; CELL LINE, TRANSFORMED; CROSS-LINKING REAGENTS; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHENYLALANINE; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 0029960763     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Monaco, J. 1992. A molecular model of MHC class-I-restricted antigen processing. Immunol. Today 13:173
2. Braciale, T. J. 1992. Antigen processing for presentation by MHC class I molecules Curr. Opin. Immunol. 4:59.
3. Neefjes, J. J., and F. Momburg. 1993 Cell biology of antigen presentation Curr. Op. Immunol. 5:27.
4. Rammensee, H.-G., K. Falk, and O. Rötzschke. 1993. Peptides naturally presented by MHC class I molecules. Annu Rev Immunol. 11:213
5. Rock, K. L., C. Gramm, L Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, and A. L. Goldberg. 1994. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78:761.
6. Fehling, H. J., W. Swat, C. Laplace, R. Kühn, K. Rajewsky, U. Müller, and H. von Boehmer. 1994. MHC class I expression in mice lacking the proteasome subunit LMP-7. Science 265 1234.
7. Cerundolo, V., A Kelly, T. Elliott, J. Trowsdale, and A. Townsend. 1995. Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport. Eur. J. Immunol. 25.554.
8. Benham, A., A. Tulp, and J. Neefjes. 1995. Synthesis and assembly of MHC-peptide complexes Immunol. Today 16.359.
9. Bijlmakers, M. J , and H L. Ploegh. 1993 Putting together an MHC class I molecule. Curr Opin. Immunol. 5:21.
10. DeMars, R., and T. Spies. 1992. New genes in the MHC that encode proteins tor antigen processing. Trends Cell Biol. 2:81.
11. Deverson, E. V , I. R. Gow, W J. Coadwell, J J. Monaco, G. W. Butcher, and J. C. Howard 1990. MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature 348:738.
12. Trowsdale, J., I. Hanson, I Mockridge, S. Beck, A. Townsend, and A. Kelly 1990. Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters Nature 348:741
13. Spies, T , M. Bresnahan, S. Bahram, D Arnold, G. Blanck, E. Mellins, D. Pious, and R. DeMars. 1990. A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. Nature 348: 744.
14. Bahram, S., D. Arnold, M. Bresnahan, J. L. Strominger, and T. Spies. 1991. Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region Proc. Natl. Acad Sci. USA 88:10094
15. Higgins, C. F. 1992. ABC transporters: from microorganisms to man. Annu Rev. Cell Biol. 8:67.
16. Kleijmeer, M J., A Kelly, H. J. Geuze, J. W. Slot, A Townsend. and J. Trowsdale. 1992. Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi, Nature 357:342
17. Powis, S. J., A. R M. Townsend, E. V. Deverson, J. Bastin, G. W Butcher, and J C. Howard 1991 Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter. Nature 354:528.
18. Kelly, A., S. H. Powis, L.-A. Kerr, I Mockridge, T. Elliott, J. Bastin, B. Uchanska-Ziegler, A. Ziegler, J Trowsdale, and A. Townsend. 1992 Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature 355:641.
19. Spies, T., V. Cerundolo, M Colonna, P. Cresswell, A. Townsend, and R. DeMars. 1992. Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer. Nature 355:644
20. Attaya, M., S Jameson, C. K Martinez, E. Hermel, C. Aldrich, J. Forman, K Fischer Lindahl, M. J. Bevan, and J. J. Monaco. 1992. Ham-2 correct the class I antigen-processing defect in RMA-S cells. Nature 355:647
21. Neefjes, J. J., F. Momburg, and G. J. Hämmerling. 1993 Selective and ATP-dependent translocation of peptides by the MHC-encoded peptide transporter Science 261:769.
22. Shepherd, J. C., T. N M Schumacher, P. G Ashton-Rickardt, S. Imaeda, H L. Ploegh, C. A. Janeway, Jr., and S. Tonegawa 1993. TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective Cell 74:577
23. Androlewicz, M. J , K. S. Anderson, and P. Cresswell. 1993. Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner. Proc. Natl. Acad. Sci. USA 90.9130.
24. Schumacher, T. N M., D V. Kantesaria, M.-T. Heemels, P. G. Ashton-Rickardt, J. C. Shepherd, K. Früh, Y. Yang, P. A Peterson, S. Tonegawa, and H. L. Ploegh. 1994. Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator. J. Exp Med. 179:533.
25. Momburg, F., J. Roelse, G. J. Hämmerling and J. J Neefjes. 1994. Peptide size selection by the major histocompatibility complex-encoded peptide transporter. J. Exp. Med. 179.1613.
26. Heemels, M.-T., and H. L. Ploegh 1994. Substrate specificity of allelic variants of the TAP peptide transporter. Immunity 1:775
27. Urban, R. G., R. M. Chicz, W. S. Lane, J L. Strominger, A. Rehm, M. J. H. Kenter, F. G. C. M. UytdeHaag, H. Ploegh, B. Uchanska-Ziegler, and A. Ziegler. 1994. A subset of HLA-B27 molecules contains peptides much longer than nonamers. Proc. Natl Acad. Sci. USA 91 1534.
28. Momburg, F., J. Roelse, J. C. Howard, G. W. Butcher, G. I. Hämmerling, and J J. Neefjes. 1994. Selectivity of MHC-encoded peptide transporters from human, mouse and rat. Nature 367:648.
29. Androlewicz, M. J., and P. Cresswell. 1994 Human transporters associated with antigen processing possess a promiscuous peptide-binding site. Immunity 1:7.
30. Powis, S. J., E. V Deverson, W. J Coadwell, A. Ciruela, N. S. Huskisson, H. Smith, G. W Butcher, and J. C. Howard 1992. Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule. Nature 357:211.
31. Heemels, M.-T., T. N M Schumacher, K Wonigeit, and H. L. Ploegh. 1993 Peptide translocation by variants of the transporter associated with antigen processing. Science 262:2059.
32. g7 (NOD/Lt) haplotype translocate similar sets of peptides. Proc. Natl. Acad. Sci. USA 91:13004
33. Obst, R , E. A. Armandola, M. Nijenhuis, F. Momburg, and G. J. Hämmerling. 1995. TAP polymorphism does not influence transport of peptide variants in mice and humans Eur. J Immunol. 25.2170.
34. Neefjes, I , E. Gottfried, J. Roelse, M. Grommë, R. Obst, G. J. Hämmerling, and F Momburg. 1995. Analysis of the fine specificity of rat, mouse and human TAP peptide transporters Eur. J. Immunol. 25:1133
35. Neisig, A., J. Roelse, A J. A. M. Sijts, F. Ossendorp, M. C. W. Feltkamp, W. M Kast, C. J M. Melief, and J. J Neefjes. 1995. Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences. J. Immunol 154:1273.
36. van Endert, P. M., R. Tampé, T. H. Meyer, R. Tisch, J.-F. Bach, and H. O. McDevitt. 1994. A sequential model for peptide binding and transport by the transporters associated with antigen processing. Immunity I:491.
37. 2-microglobulin binding to the transporter associated with antigen processing (TAP1 and TAP2). Proc. Natl. Acad. Sci. USA 91:12716.
38. Powis, S. H., S. Tonks, I. Mockridge, A. P. Kelly, J. G. Bodmer, and J. Trowsdale. 1993. Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2. Immunogenetics 37:373.
39. O'Reilly, D R , Miller, L. K., and Luckow, V. A. 1994. Baculovirus Expression Vectors: A Laboratory Manual. Oxford University Press, New York.
40. Brunner, J. 1993. New photolabeling and crosslinking methods. Annu. Rev. Biochem. 62.483.
41. Salter, R. D., and P. Cresswell. 1986. Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid. EMBO J. 5:943.
42. Greenberger, L. M., C. J. Lisanti, J. T. Silva, and S. B. Horwitz 1991. Domain mapping of the photoaffinity drug-binding sites in P-glycoprotein encoded by mouse mdr lb. J. Biol. Chem. 266:20744.
43. Greenberger, L. M. 1993. Major photoaffinity drug labeling sites for iodoaryl azidoprazosin in P-glycoprotein are within, or immediately C-terminal to, transmembrane domains 6 and 12. J. Biol. Chem. 268:11417.
44. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680
45. Schagger, H., and G. von Jagow. 1987. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem. 166.368.
46. Meyer, T. H., P. M. van Endert, S. Uebel, B. Ehring, and R. Tampé. 1994. Functional expression and purification of the ABC transporter complex associated with antigen processing (TAP) in insect cells FEBS Lett 351:443.
47. Gottesman, M M., and I. Pastan. 1993. Biochemistry of the multidrug resistance mediated by the multidrug transporter Annu. Rev. Biochem. 62:385.
48. Zhang, F., J. A. Sheps, and V. Ling. 1993. Complementation of transport-deficient mutants of Escherichia coli α-hemolysin by second-site mutations in the transporter hemolysin B. J Biol. Chem. 268:19889.
49. Covitz, K -M. Y., C. H. Panagiotidis, L.-I. Hor, M. Reyes, N. A. Treptow, and H. A. Shuman. 1994. Mutations that alter the transmembrane signalling pathway in an ATP binding cassette (ABC) transporter. EMBO J. 13.1752.
50. Anderson, M P., R J. Gregory, S. Thompson, D. W Souza, S. Paul, R. C. Mulligan, A. E Smith, and M. J. Welsh. 1991. Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science 253:202.
51. Bruggeman, E. P., S. J. Currier, M. M. Gottesman, and I. Pastan. 1992. Characterization of the azidopine and vinblastine binding site of P-glycoprotein. J. Biol. Chem. 29:21020.