Significance of inducible nitric oxide synthase in acute myocarditis caused by Trypanosoma cruzi (Tulahuen strain)

International Journal for Parasitology

Volumn 32, Issue 7, 2002, Pages 897-905

  Chandra, Madhulika ^a   Tanowitz, Herbert B ^a   Petkova, Stefka B ^a   Huang, Huan ^a   Weiss, Louis M ^a   Wittner, Murray ^a   Factor, Stephen M ^a   Shtutin, Vitaliy ^a   Jelicks, Linda A ^a   Chan, John ^a   Shirani, Jamshid ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Chagas' disease; Echocardiography; Inducible nitric oxide synthase; Knockout mice; Nitric oxide; Trypanosoma cruzi

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

CHAGAS DISEASE; PARASITOLOGY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CHAGAS DISEASE; CONTROLLED STUDY; DIASTOLE; DISEASE COURSE; HEART DILATATION; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE SIZE; HEART RATE VARIABILITY; HEART RIGHT VENTRICLE; KNOCKOUT MOUSE; MOUSE; MOUSE STRAIN; MYOCARDITIS; NONHUMAN; STRAIN DIFFERENCE; SYSTOLE; TRANSTHORACIC ECHOCARDIOGRAPHY; TRYPANOSOMA CRUZI; WILD TYPE;

ANIMALS; CHAGAS DISEASE; CYTOKINES; ELECTROCARDIOGRAPHY; GENE EXPRESSION REGULATION; HISTOCYTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDITIS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PARASITEMIA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, PROTOZOAN; TRYPANOSOMA CRUZI;

MURINAE; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0036273749     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(02)00028-0     Document Type: Article

References (46)

1. Modulation of chemokine production and inflammatory responses in interferon-γ and tumor necrosis factor-R1-deficient mice during Trypanosoma cruzi infections
2. Nitric oxide attenuates cardiac myocyte contraction
3. Cardio protective effects of verapamil on myocardial structure and function in a murine model of chronic Trypanosoma cruzi infection (Brazil strain): An echocardiographic study
4. Temporal expression of pro-inflammatory cytokines and inducible nitric oxide synthase in experimental acute chagasic cardiomyopathy
5. Differential regulation of nitric oxide synthase isoforms in experimental acute chagasic cardiomyopathy
6. Prolonged sinus node recovery time in humans after the intracoronary administration of a nitric oxide synthase inhibitor
7. Abnormalities of the coronary microcirculation in acute murine Chagas' disease
8. Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice
9. Nitric oxide and viral cardiomyopathy
10. Negative inotropic effects of cytokines on the heart mediated by nitric oxide
11. Contractile depression and expression of proinflammatory cytokines and iNOS in viral myocarditis
12. The microbiocidal activity of interferon-gamma treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by IL-10 and transforming growth factor-beta
13. Expression of inducible nitric oxide synthase in experimental viral myocarditis
14. Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase
15. Defective nitric oxide effector functions leads to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase
16. Tumor necrosis factor α-mediated toxic shock in Trypanosoma cruzi-infected interleukin 10-deficient mice
17. Trypanosoma cruzi infection induces myocardial nitric oxide synthase
18. Expression of cardiac cytokines and inducible form of nitric oxide synthase (NOS2) in Trypanosoma cruzi-infected mice
19. Application of cardiac gated magnetic resonance imaging in murine Chagas' disease
20. Sodium nitroprusside increases pacemaker rhythm of sinoatrial nodes via nitric oxide-cGMP pathway
21. Nitric oxide and cardiac function
22. Altered response to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
23. Fas-FasL interaction modulates nitric oxide production in Trypanosoma cruzi-infected mice
24. Tumor necrosis factor in the heart
25. A selective inhibitor for inducible nitric oxide synthase improves hypotension and lactic acidosis in canine endotoxic shock
26. Nitric oxide can increase heart rate by stimulating the hyperpolarisation-activated inward current
27. Nitric oxide synthase II mRNA expression in cardiac tissue of patients with heart failure undergoing cardiac transplantation
28. Force frequency effect is a powerful determinant of myocardial contractility in the mouse
29. The role of endothelin in the pathogenesis of Chagas' disease
30. Differential nitric oxide synthase activity in ischemic and idiopathic dilated cardiomyopathy
31. Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes
32. CD4 Th1 but not Th2 clones efficiently activate macrophages to eliminate Trypanosoma cruzi through nitric oxide dependent mechanism
33. Coronary microvascular abnormalities in Chagas' disease
34. Intracellular co-localisation of Trypanosoma cruzi and inducible nitric oxide synthase (iNOS): Evidence for dual pathway of iNOS induction
35. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of two-dimensional Echocardiograms
36. Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages
37. The role of the NO pathway in the control of cardiac function
38. Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: Tissue parasitism and endogenous IFN-γ as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi
39. Cytokine gene expression of endothelial cells infected with Trypanosoma cruzi
40. Compromised microcirculation in acute murine Trypanosoma cruzi infection
41. Tumour necrosis factor (cachectin) production during experimental Chagas' disease
42. Trypanosoma cruzi: Role of the immune response in the natural resistance of inbred strains of mice
43. Nitric oxide is involved in control of Trypamosoma cruzi-induced parasitemia and directly kills the parasite in vitro
44. The cysteine-cysteine family of chemokines RANTES, MIP-1 alpha, and MIP-1beta induce trypanocidal activity in human macrophages via nitric oxide
45. Involvement of inducible nitric oxide synthase in the inflammatory process of myocardial infarction
46. The role of inducible nitric oxide synthase in the host response to Coxsackievirus myocarditis