Modulation of marrow stromal osteoblast adhesion on biomimetic oligo[poly(ethylene glycol) fumarate] hydrogels modified with Arg-Gly-Asp peptides and a poly(ethylene glycol) spacer

Journal of Biomedical Materials Research

Volumn 61, Issue 2, 2002, Pages 169-179

  Shin, Heungsoo ^a   Jo, Seongbong ^a   Mikos, Antonios G ^a  

^a Rice University   (United States)

Author keywords

Biodegradable hydrogels; Bone tissue engineering; Cell attachment; Injectable hydrogels; RGD

Indexed keywords

ADHESION; CELLS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT;

CELL SEEDINGS;

HYDROGELS;

FUMARIC ACID DERIVATIVE; MACROGOL; OLIGOPEPTIDE; SYNTHETIC PEPTIDE; ARGINYL GLYCYL ASPARTIC ACID (AMINO POLYETHYLENE GLYCOL); ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYL-GLYCYL-ASPARTIC ACID-(AMINO-POLYETHYLENE GLYCOL); ARGINYLGLYCYLASPARTIC ACID; BIOMATERIAL; CROSS LINKING REAGENT; MACROGOL DERIVATIVE; OLIGO(POLY(ETHYLENE GLYCOL)FUMARATE); POLYESTER;

ANIMAL CELL; BINDING COMPETITION; BIODEGRADABILITY; BONE TISSUE; CELL ADHESION; CELL DIFFERENTIATION; CONFERENCE PAPER; CROSS LINKING; CYTOSKELETON; FILM; HYDROGEL; MALE; MOLECULAR WEIGHT; NONHUMAN; OSTEOBLAST; PEPTIDE SYNTHESIS; PHASE CONTRAST MICROSCOPY; RAT; TISSUE ENGINEERING; ANIMAL; ARTICLE; BONE MARROW CELL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; METHODOLOGY; NON-PROGRAMMATIC; STROMA CELL; WISTAR RAT;

NON-PROGRAMMATIC;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE MARROW CELLS; CELL ADHESION; CROSS-LINKING REAGENTS; HYDROGELS; MALE; OLIGOPEPTIDES; OSTEOBLASTS; POLYESTERS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; STROMAL CELLS; TISSUE ENGINEERING;

EID: 0036268868     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.10193     Document Type: Conference Paper

References (30)

1. Bioactive biomaterials
2. Molecular engineering of materials for bioreactivity
3. Endothelial cell migration on surfaces modified with immobilized adhesive peptides
4. Three-dimensional migration of neurites is mediaed by adhesion site density and affinity
5. Alginate hydrogel linked with synthetic oligopeptide derived from BMP-2 allows ectopic osteoinduction in vivo
6. Polymeric biomaterials with degradation sites for proteases involved in cell migration
7. Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension
8. Design and function of novel osteoblast-adhesive peptides for chemical modification of biomaterials
9. Surface modification for controlled studies of cell-ligand interactions
10. Soft-tissue augmentation with injectable alginate and syngeneic fibroblasts
11. Alginate hydrogels as synthetic extracellular matrix materials
12. Synthesis and characterization of oligo(poly(ethylene glycol)fumarate) macromer
13. Effect of poly(ethylene glycol) molecular weight on tensile and swelling properties of oligo (poly(ethylene glycol) fumarate) hydrogels for cartilage tissue engineering
14. Synthetic biodegradable polymer networks modulating marrow stromal osteoblast adhesion
15. Synthesis and properties of malic acid-containing functional polymers
16. Marrow stromal osteoblast function on a poly(propylene fumarate)/beta-tricalcium phosphate biodegradable orthopaedic composite
17. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing
18. Retinal pigment epithelial cell function on substrates with chemically micropatterned surfaces
19. The microenvironment of immobilized Arg-Gly-Asp peptides is an important determinant of cell adhesion
20. Synthesis of poly(ethylene glycol)-tethered poly(propylene fumarate) and its modification with GRGD peptides
21. Tethered TGF-b increases extracellular matrix production of vascular smooth muscle cells
22. Effect of the substituents on radical copolymerization of dialkyl fumarate with some vinyl monomers
23. New prospective in cell adhesion: RGD and integrin
24. Three dimension extracellular matrix engineering in the nervous system
25. Ectopic bone formation by marrow stromal osteoblast transplantation using poly (DL-lactide-coglycolic acid) foams implanted into the rat mesentery
26. 3-mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation
27. The effect of peptide surface density on mineralization of a matrix deposited by osteogenic cells
28. Selective RGD-mediated adhesion of osteoblast at surfaces of implant
29. RGDS tetrapeptide binds to osteoblasts and inhibits fibronectin-mediated adhesison
30. Osteoblast adhesion on biomaterials