Immunolocalization of microsomal glutathione S-transferase in rat tissues

Drug Metabolism and Disposition

Volumn 25, Issue 1, 1997, Pages 12-20

  Otieno, Monicah A ^b   Baggs, Raymond B ^b   Hayes, John D ^b   Anders, M W ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE;

ANIMAL TISSUE; ARTICLE; DRUG DEGRADATION; DRUG DETOXIFICATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; IMMUNOHISTOCHEMISTRY; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION;

ADRENAL GLANDS; ANIMALS; BLOTTING, WESTERN; BRAIN CHEMISTRY; GLUTATHIONE TRANSFERASE; IMMUNOHISTOCHEMISTRY; INTESTINES; KIDNEY; LIVER; LUNG; MALE; MICROSOMES, LIVER; PANCREAS; RATS; RATS, INBRED F344; TESTIS; TISSUE DISTRIBUTION;

EID: 0031030989     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. L. F. Chasseaud: The role of glutathione and glutathione S-transferases in the metabolism of chemical carcinogens and other electrophilic agents. Adv. Cancer Res. 29, 175-274 (1979).
2. B. Mannervik and M. Widersten: Human glutathione transferases: classification, tissue distribution, structure, and functional properties. In "Advances in Drug Metabolism in Man" (G. M. Pacific) and G. N. Fracchia, eds.), pp. 407-459. Commission of the European Communities, Luxembourg, 1995.
3. B. Ketterer and L. G. Christodoulides: Enzymology of the cytosolic glutathione S-transferases. Adv. Pharmacol. 27, 37-69 (1994).
4. J. D. Hayes and D. J. Pulford: The glutathione S-transferase supergene family: regulation of GST and the contribution of isoenzymes to cancer chemoprotection and drug resistance. CRC Crit. Rev. Biochem. Mol. Biol. 30, 445-600 (1995).
5. D. J. Harrison, R. Kharbanda, D. S. Cunningham, L. I. McLellan, and J. D. Hayes: Distribution of glutathione S-transferase isoenzymes in human kidney: basis for possible markers of renal injury. J. Clin. Pathol. 42, 624-628 (1989).
6. A. Sundberg, E. L. Appelkvist, G. Dallner, and R. Nilsson: Glutathione transferases in the urine: sensitive methods for detection of kidney damage induced by nephrotoxic agents in humans. Environ. Health Perspect. 102 (Suppl. 3), 293-296 (1994).
7. B. Mannervik and U. H. Danielson: Glutathione transferases - structure and catalytic activity. CRC Crit. Rev. Biochem. 23, 281-334 (1988).
8. P. Kraus: Resolution, purification and some properties of three glutathione transferases from rat liver mitochondria. Hoppe-Seyler's Z. Physiol. Chem. 361, 9-15 (1980).
9. C. M. Ryle and T. J. Mantle: Studies on the glutathione S-transferase activity associated with rat liver mitochondria. Biochem. J. 222, 553-556 (1984).
10. J. M. Harris, D. J. Meyer, B. Coles, and B. Ketterer: A novel glutathione transferase (13-13) isolated from the matrix of rat liver mitochondria having structural similarity to class theta enzymes. Biochem. J. 278, 137-141 (1991).
11. F. P. Guengerich: Metabolism and genotoxicity of dihaloalkanes. Adv. Pharmacol. 27, 211-236 (1994).
12. T. A. Baillie and K. Kassahun: Reversibility in glutathione-conjugate formation. Adv. Pharmacol. 27, 165-183 (1994).
13. T. J. Monks and S. S. Lau: Glutathione conjugates as a mechanism for the transport of reactive metabolites. Adv. Pharmacol. 27, 183-210 (1994).
14. W. Dekant, S. Vamvakas, and M. W. Anders: Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate β-lyase pathway. Adv. Pharmacol. 27, 115-162 (1994).
15. C. Andersson, E. Mosialou, R. Weinander, and R. Morgenstern: Enzymology of microsomal glutathione S-transferase. Adv. Pharmacol. 27, 19-35 (1994).
16. M. Söderström, S. Hammarström, and B. Mannervik: Leukotriene C synthase in mouse mastocytoma cells. Biochem. J. 250, 713-718 (1988).
17. J. L. DeJong, R. Morgenstern, H. Jörnvall, J. W. DePierre, and C.-P. D. Tu: Gene expression of rat and human microsomal glutathione S-transferases. J. Biol. Chem. 263, 8430-8436 (1988).
18. G. Lundqvist and R. Morgenstern: Ontogenesis of rat liver microsomal glutathione transferase. Biochem. Pharmacol. 50, 421-423 (1995).
19. M. J. Kelner, M. N. Stokely, N. E. Stovall, and M. A. Montoya: Structural organization of the human microsomal glutathione S-transferase gene (GST12). Genomics, in press.
20. L. I. McLellan, C. R. Wolf, and J. D. Hayes: Human microsomal glutathione S-transferase. Its involvement in the conjugation of hexachloro-1,3-butadiene with glutathione. Biochem. J. 258, 87-93 (1989).
21. E. Mosialou, G. Ekstrom, A. E. P. Adang, and R. Morgenstern: Evidence that rat liver microsomal glutathione transferase is responsible for glutathione-dependent protection against lipid peroxidation. Biochem. Pharmacol. 45, 1645-1651 (1993).
22. Y. Aniya and M. W. Anders: Activation of rat liver microsomal glutathione S-transferase by reduced oxygen species. J. Biol. Chem. 264, 1998-2002 (1989).
23. R. Morgenstern, G. Lundqvist, G. Andersson, L. Balk, and J. W. DePierre: The distribution of microsomal glutathione transferase among different organelles, different organs, and different organisms. Biochem. Pharmacol. 33, 3609-3614 (1984).
24. J. D. Hayes and T. J. Mantle: Use of immuno-blot techniques to discriminate between the glutathione S-transferase Yf, Yk, Ya, Yn/Yb and Yc subunits and to study their distribution in extrahepatic tissues. Biochem. J. 233, 779-788 (1986).
25. E. Tanaka and M. W. Anders: Biosynthesis of S-(2-chloro-1,1,2-trifluoroethyl)glutathione in rat and human hepatocytes and in Hep G2 cells. Drug Metab. Dispos. 23, 48-54 (1995).
26. P. C. Hayes, D. J. Harrison, I. A. D. Bouchier, L. I. McLellan, and J. D. Hayes: Cytosolic and microsomal glutathione S-transferase isoenzymes in normal human liver and intestinal epithelium. Gut 30, 854-859 (1989).
27. J. A. H. Campbell, A. V. Corrigall, A. Guy, and R. E. Kirsch: Immunohistologic localization of alpha, mu, and pi class glutathione S-transferases in human tissues. Cancer 67, 1608-1613 (1991).
28. A. G. M. Sundberg, R. Nilsson, E.-L. Appelkvist, and G. Dallner: Immunohistochemical localization of α and π class glutathione transferases in normal human tissues. Pharmacol. Toxicol. 72, 321-331 (1993).
29. K. Kamisaka, I. Listowsky, Z. Gatmaitan, and I. M. Arias: Interactions of bilirubin and other ligands with ligandin. Biochemistry 14, 2175-2180 (1975).
30. H. Maruyama and I. Listowsky: Preferential binding of steroids by anionic forms of rat glutathione S-transferase. J. Biol. Chem. 259, 12449-12455 (1984).
31. E. Mosialou and R. Morgenstern: Activity of rat liver microsomal glutathione transferase towards products of lipid peroxidation and studies on the effect of inhibitors on glutathione-dependent protection against lipid peroxidation. Arch. Biochem. Biophys. 275, 289-294 (1989).
32. S. J. Hargus, M. E. Fitzsimmons, Y. Aniya, and M. W. Anders: Stereochemistry of the microsomal glutathione S-transferase catalyzed addition of glutathione to chlorotrifluoroethene. Biochemistry 30, 717-721 (1991).
33. M. Koob and W. Dekant: Metabolism of hexafluoropropene. Evidence for bioactivation by glutathione conjugate formation in the kidney. Drug. Metab. Dispos. 18, 911-916 (1990).
34. J. A. Redick, W. B. Jakoby, and J. Baron: Immunohistochemical localization of glutathione S-transferases in livers of untreated rats. J. Biol. Chem. 257, 15200-15203 (1982).
35. P. Terrier, A. J. Townsend, J. M. Coindre, T. J. Triches, and K. H. Cowan: An immunohistochemical study of pi class glutathione S-transferase expression in normal human tissue. Am. J. Pathol. 137, 845-853 (1990).
36. B. Rozell, H.-A. Hansson, C. Guthenberg, M. K. Tahir, and B. Mannervik: Glutathione transferases of classes α, μ and π show selective expression in different regions of rat kidney. Xenobiotica 23, 835-849 (1993).
37. L. H. Overby, S. Gardlik, R. M. Philpot, and C. J. Serabjit-Singh: Unique distribution profiles of glutathione S-transferases in regions of kidney, ureter, and bladder of rabbit. Lab. Invest. 70, 468-478 (1994).
38. M. W. Anders and W. Dekant: Renal xenobiotic metabolism: Role in bioactivation of nephrotoxic xenobiotics. In "Renal Disposition and Nephrotoxicity of Xenobiotics" (M. W. Anders, W. Dekant, D. Henschler, H. Oberleithner, and S. Silbernagl, eds.), pp. 155-183. Academic Press, San Diego, 1993.
39. C. D. Hassall, A. J. Gandolfi, R. C. Duhamel, and K. Brendel: The formation and biotransformation of cysteine conjugates of halogenated ethylenes by rabbit renal tubules. Chem.-Biol. Interact. 49, 283-297 (1984).
40. L. Bäckman, E.-L. Appelkvist, O. Ringdén, and G. Dallner: Glutathione transferase in the urine: a marker for post-transplant tubular lesions. Kidney Int. 33, 571-577 (1988).
41. L. Bäckman, E. L. Appelkvist, O. Ringdén, and G. Dallner: Urinary levels of basic glutathione transferase as an indicator of proximal tubular damage in renal transplant recipients. Transplant. Proc. 21, 1514-1516 (1989).
42. A. G. Sundberg, E. L. Appelkvist, L. Backman, and G. Dallner: Urinary pi-class glutathione transferase as an indicator of tubular damage in the human kidney. Nephron 67, 308-316 (1994).
43. A. G. Sundberg, E. L. Appelkvist, L. Backman, and G. Dallner: Quantitation of glutathione transferase-pi in the urine by radioimmunoassay. Nephron 66, 162-169 (1994).
44. P. J. Carder, R. Hume, A. A. Fryer, R. C. Strange, J. Lauder, and J. E. Bell: Glutathione S-transferase in human brain. Neuropathol. Appl. Neurobiol. 16, 293-303 (1990).
45. J. A. Johnson, A. El Barbary, S. E. Kornguth, J. F. Brugge, and F. L. Siegel: Glutathione S-transferase isoenzymes in rat brain neurons and glia. J. Neurosci. 13, 2013-2023 (1993).
46. M. Abramovitz, H. Homma, S. Ishigaki, F. Tansey, W. Cammer, and I. Listowsky: Characterization and localization of glutathione-5-transferases in rat brain and binding of hormones, neurotransmitters, and drugs. J. Neurochem. 50, 50-57 (1988).
47. T. K. Makar, M. Nedergaard, A. Preuss, A. S. Gelbard, A. S. Perumal, and A. J. L. Cooper: Vitamin E, ascorbate. glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes plan an important role in antioxidative processes in the brain. J. Neurochem. 62, 45-53 (1994).
48. R. Dixit, H. Mukhtar, P. K. Seth, and C. R. Krishna Murti: Conjugation of acrylamide with glutathione catalysed by glutathione-S-transferases of rat liver and brain. Biochem. Pharmacol. 30, 1739-1744 (1981).
49. B. Ketterer and D. J. Meyer: Glutathione transferases: a possible role in the detoxication and repair of DNA and lipid hydroperoxides. Mutat. Res. 214, 33-40 (1989).
50. E. Mosialou, F. Piemonte, C. Andersson, R. M. E. Vos, P. J. Van Bladeren, and R. Morgenstern: Microsomal glutathione transferase: lipid-derived substrates and lipid dependence. Arch. Biochem. Biophys. 320, 210-216 (1995).
51. C. F. Bennett, D. L. Spector, and L. C. Yeoman: Nonhistone protein BA is a glutathione S-transferase localized to interchromatinic regions of the cell nucleus. J. Cell Biol. 102, 600-609 (1986).
52. N. Patel, G. Birner, W. Dekant, and M. W. Anders: Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and 5-(1,2-dichlorovinyl)-L-cystine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions. Drug Merab. Dispos. 22, 143-147 (1994).
53. C. A. Partridge, S. V. Singh, T. D. Hong, C. Theodore, D. D. Dao, and Y. C. Awasthi: Rat lung glutathione S-transferases: subunit structure and the interrelationships with the liver enzymes. Int. J. Biochem. 17, 331-340 (1985).
54. S. Anttila, A. Hirvonen, H. Vainio, K. Husgafvel-Pursiainen, J. D. Hayes, and B. Ketterer: Immunocytochemical localization of glutathione S-transferases in human lung. Cancer Res. 53, 5643-5648 (1993).
55. D. B. Coursin, H. P. Cihla, T. D. Oberley, and L. W. Oberley: Immunolocalization of antioxidant enzymes and isozymes of glutathione S-transferase in normal rat lung. Am. J. Physiol 263, L679-L691 (1992).
56. L. M. Pinkus, J. N. Ketley, and W. B. Jakoby: The glutathione 5-transferases as a possible detoxication system of rat intestinal epithelium. Biochem. Pharmacol. 26, 2359-2363 (1977).
57. G. Clifton and N. Kaplowitz: The glutathione S-transferases of the small intestine in the rat. Cancer Res. 37, 788-791 (1977).
58. J. M. Daly, L. B. G. Tee, P. S. Dates, R. G. H. Morgan, and C. T. Yeoh: Glutathione S-transferase (μ class) as an early marker of azaserine-induced foci in the rat pancreas. Carcinogenesis 12, 1237-1240 (1991).
59. C. C. Reddy, C.-P. D. Tu, J. R. Burgess, C.-Y. Ho, R. W. Scholz, and E. J. Massaro: Evidence for the occurrence of selenium-independent glutathione peroxidase activity in rat liver microsomes. Biochem. Biophys. Res. Commun. 101, 970-978 (1981).
60. J. P. Veri, L. Hermo, and R. Robaire: Immunocytochemical localization of glutathione S-transferase Yo subunit in the rat testis and epididymis. J. Androl. 15, 415-434 (1994).
61. 2 subunits of glutathione S-transferase in the testis and epididymis of adult rats. Microsc. Res. Tech. 30, 1-23 (1995).
62. B. Robaire and R. S. Viger: Regulation of epididymal epithelial cell functions. Biol. Reprod. 52, 226-236 (1995).
63. M. Shimoji and Y. Aniya: Glutathione S-transferases in rat testis microsomes: comparison with liver transferase. J. Biochem. 115, 1128-1134 (1994).
64. W. Dekant, M. W. Anders, and T. J. Monks: Bioactivation of halogenated xenobiotics by S-conjugate formation. In "Renal Disposition and Nephrotoxicity of Xenobiotics" (M. W. Anders, W. Dekant, D. Henschler, H. Oberleithner, and S. Silbernagl, eds.), pp. 187-215. Academic Press, San Diego, 1993.
65. M. W. Anders, W. Dekant, and S. Vamvakas: Glutathione-dependent bioactivation of xenobiotics. In "Biothiols" (L. Packer and E. Cadenas, eds.), pp. 135-163. Marcel Dekker, New York, 1995.