t(1;3)(p36;p21) is a recurring therapy-related translocation

Genes Chromosomes and Cancer

Volumn 34, Issue 2, 2002, Pages 186-192

  Sato, Yuko ^a   Izumi, Tohru ^b   Kanamori, Hirakazu ^c   Davis, Elizabeth M ^d   Miura, Yasusada ^e   Larson, Richard A ^d   Le Beau, Michelle M ^d   Ozawa, Keiya ^b   Rowley, Janet D ^d  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d UNIVERSITY OF CHICAGO   (United States)

^e Social Insurance Central General Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CHROMOSOME BAND; CHROMOSOME BREAKAGE; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; COSMID; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FREQUENCY; HEMATOLOGIC DISEASE; HUMAN; KARYOTYPING; MALE; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; CHILD; CHROMOSOME BREAKAGE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 3; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOID, CHRONIC; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; RECURRENCE; TRANSLOCATION, GENETIC;

EID: 0036265583     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.10055     Document Type: Article

References (20)

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2. Large deletions 5′ to ETO breakpoint were observed in 10% of patients with t(8;21)-positive AML
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6. Cytogenetic analysis of hematological malignant diseases
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8. A novel gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells
9. Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: Identification of 11q23 translocation breakpoints with a yeast artificial chromosome
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11. Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3; 11)(p21;q23)
12. Second relapse of acute promyelocytic leukemia (ANLL-M3) with t(15;17) and t(1;3)(p36; q21)
13. Heterogeneity in the breakpoints in balanced rearrangements involving band 12p13 in hematologic malignancies identified by fluorescence in sim hybridization: TEL(ETV6) is involved in only one half
14. Chromosomal instability in chromosome band 12p13: Multiple breaks leading to complex rearrangements including cytogenetically undetectable sub-clones
15. 3p21 is a recurrent treatment-related breakpoint in myelodysplastic syndrome and acute myeloid leukemia
16. Identification of breakpoint cluster regions at 1p36.3 and 3q21 in hematologic malignancies with t(1;3)(p36;q21)
17. Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: Progress toward the isolation of a lung cancer TSG
18. The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberrations in different hematological malignancies