Bone cell mitogenic action of fluoroaluminate and aluminum fluoride but not that of sodium fluoride involves upregulation of the insulin-like growth factor system

Bone

Volumn 30, Issue 5, 2002, Pages 705-711

  Lau, K H ^a   Goodwin, C ^a,b   Arias, M ^a,b   Mohan, S ^a,b   Baylink, D J ^a,b  

^a Jerry L Pettis Memorial VA Medical Center   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aluminum fluoride; Bone cells (human); Fluoroaluminate; Insulin like growth factor; Proliferation; Sodium fluoride

Indexed keywords

ALUMINUM FLUORIDE; FLUORIDE SODIUM; FLUOROALUMINATE; MESSENGER RNA; PROTEIN; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5;

ARTICLE; BONE CELL; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; MITOGENESIS; OSTEOSARCOMA CELL; REGULATORY MECHANISM;

ALUMINUM; ALUMINUM COMPOUNDS; BONE NEOPLASMS; CELL DIVISION; DNA; FLUORIDES; FLUORINE; GENE EXPRESSION; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; INSULIN-LIKE GROWTH FACTOR II; MITOGENS; OSTEOSARCOMA; RNA, MESSENGER; SODIUM FLUORIDE; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0036252124     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(02)00671-3     Document Type: Article

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