Thrombin induces production of growth factors from aortic smooth muscle cells

Journal of Surgical Research

Volumn 82, Issue 1, 1999, Pages 61-66

  Cucina, Alessandra ^a   Borrelli, Valeria ^a   Di Carlo, Anna ^a   Pagliei, Sabrina ^a   Corvino, Valentina ^a   Santoro D'Angelo, Luciana ^a   Cavallaro, Antonino ^a   Sterpetti, Antonio V ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

bFGF; Growth factors; PDGF; Smooth muscle cell; Thrombin

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; MONOCLONAL ANTIBODY; PLATELET DERIVED GROWTH FACTOR AA; THROMBIN; THYMIDINE; TRITIUM;

ANIMAL CELL; AORTA MEDIA; ARTERY INTIMA PROLIFERATION; ARTERY RECONSTRUCTION; ARTICLE; CATTLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; MITOGENICITY; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; THORACIC AORTA;

EID: 0032839610     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1998.5514     Document Type: Article

References (43)

1. Ferns G. A. A., Raines E. W., Sprugel K. H., Motani A. S., Reidy M. A., Ross R. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science. 253:1991;1129.
2. Thyberg J., Hedin U., Sjolund M., Palmberg L., Bottger B. A. Regulation of differentiated properties and proliferation of arterial smooth muscle cells. Arteriosclerosis. 10:1990;966.
3. Lindner V., Reidy M. A. Proliferation of smooth muscle cells after vascular injury is inhibited by our antibody against basic fibroblast growth factor. Proc. Natl. Acad. Sci. USA. 88:1991;3739.
4. Sterpetti A. V., Cucina A., Lepidi S., Randone B., Stipa F., Aromatario C., Travi D., Santoro-D'Angelo L., Cavallaro A., Stipa S. Progression and regression of myointimal hyperplasia in experimental vein grafts depends on platelet-derived growth factor and basic fibroblastic growth factor production. J. Vasc. Surg. 23:1996;568.
5. Furie B., Furie B. C. The molecular basis of blood coagulation. Cell. 53:1988;505.
6. Hatton M. W., Moar S. L., Richardson M. Deendothelialization in vivo initiates thrombogenic reaction at the rabbit aorta surface. Correlation of uptake of fibrinogen and antithrombin III with thrombin generation by the exposed subendothelium. Am. J. Pathol. 135:1989;499.
7. Bar-Shavit R., Benezra M., Sabbah V., Bode W., Vlodavsky I. Thrombin as a multifunctional protein: Induction of cell adhesion and proliferation. Am. J. Respir. Cell. Mol. Biol. 6:1992;123.
8. Groves H. M., Kinlough-Rathbone R. L., Richardson M., Moore S., Mustard J. F. Platelet interaction with damaged rabbit aorta. Lab. Invest. 40:1979;194.
9. Gelehrter T. D., Sznycer-Laszuk R. Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells. J. Clin. Invest. 77:1986;165.
10. Sporn L. A., Marder V. J., Wagner D. D. Von Willebrand factor released from Wiebel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood. 69:1987;1531.
11. Prescott S. M., Zimmerman G. A., McIntyre T. M. Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetil-sn. Proc. Natl. Acad. Sci. USA. 81:1984;3534.
12. Zimmerman G. A., McIntyre T. M., Prescott S. M. Production of platelet-activating factor by human vascular endothelial cells: Evidence for a requirement for specific agonists and modulation by prostacyclin. Circulation. 72:1985;718.
13. Bar-Shavit R., Eldor A., Vlodavsky I. Binding of thrombin to subendothelial extracellular matrix: Protection and expression of functional properties. J. Clin. Invest. 84:1989;1096.
14. Hattori R., Hamilton K. K., Fugate R. D., McEver R. P., Sims P. J. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J. Biol. Chem. 264:1989;7768.
15. Quillen J. E., Sellke F. W., Armstrong M. L., Harrison D. G. Long-term cholesterol feeding alters the reactivity of primate coronary microvessels to platelet products. Arterioscler. Thromb. 11:1991;639.
16. Ku D. D. Coronary vascular reactivity after acute myocardial ischemia. Science. 218:1982;576.
17. Shultz P. J., Knauss T. C., Menè P., Abboud H. E. Mitogenic signals for thrombin in mesangial cells: Regulation of phospholipase C and PDGF genes. Am. J. Physiol. 257:1989;F366.
18. 0. J. Biol. Chem. 265:1990;22292.
19. Graham D. J., Alexander J. J. The effects of thrombin on bovine aortic endothelial and smooth muscle cells. J. Vasc. Surg. 11:1990;307.
20. Sterpetti A. V., Cucina A., Santoro-D'Angelo L., Cardillo B., Cavallaro A. Shear stress modulates the proliferation rate, protein synthesis, and mitogenic activity of arterial smooth muscle cells. Surgery. 113:1993;691.
21. Dodt J., Muller H. P., Seemuller V., Chang J. Y. The complete amino acid sequence of hirudin, a thrombin specific inhibitor. FEBS Lett. 165:1984;180.
22. Gefter M. L., Margulies D. H., Scharff M. D. A simple method for polyethylene glycol promoted hybridization of mouse myeloma cells. Somat. Cell. Genet. 3:1977;231.
23. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature. 362:1993;1007.
24. Nakano T., Raines E. W., Abraham J. A., Wenzel F. G. IV, Higashiyama S., Klagsbrun M., Ross R. Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells. J. Biol. Chem. 268:1993;22941.
25. Chaikof E. L., Caban R., Yan C., Rao G. N., Runge M. S. Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences. J. Biol. Chem. 270:1995;7431.
26. Harker L. A., Hanson S. R., Runge M. S. Thrombin hypothesis of thrombus generation and vascular lesion formation. Am. J. Cardiol. 75:1995;12B.
27. Walters T. K., Gorog D. A., Wood R. F. M. Thrombin generation following arterial injury is a critical initiating event in the pathogenesis of the proliferative stages of the atherosclerotic process. J. Vasc. Res. 31:1994;173.
28. Hanson S. R., Wilcox J. N., Kelly A. B., Lumsden A. B., Scott N. A., Harker L. A. Thrombin mediation of arterial smooth muscle cell (SMC) proliferation after mechanical vascular injury in non-human primates (Abstract). Blood. 80:1992;166a.
29. Wilcox J. N., Rodriguez J., Subramanian R., Ollerenshaw J., Zhong C., Hayzer D. J., Horaist C., Hanson S. R., Lumsden A., Salam T. A. Thrombin receptor expression in vascular lesion formation. Circ. Res. 75:1994;1029.
30. Zhong C., Hayzer D. J., Corson M. A., Runge M. S. Molecular cloning of the rat vascular smooth muscle thrombin receptor. J. Biol. Chem. 267:1992;16975.
31. Grand R. J. A., Turnell A. S., Grabham P. W. Cellular consequences of thrombin-receptor activation. Biochem. J. 313:1996;353.
32. Kanthou C., Parry G., Wijelath E., Kakkar V. V., Demoliou-Mason C. Thrombin-induced proliferation and expression of platelet-derived growth factor-A chain gene in human vascular smooth muscle cells. FEBS Lett. 314:1992;143.
33. Okazaki H., Majesky M. W., Harker L. A., Schwartz S. M. Regulation of platelet-derived growth factor ligand and receptor gene expression by α-thrombin in vascular smooth muscle cells. Circ. Res. 71:1992;1285.
34. Weiss R. H., Ives H. E. Dissociation between activation of growth-related genes and mitogenic responses of neonatal vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 181:1991;617.
35. Stouffer G. A., Sarembock I. J., McNamara C. A., Gimple L. W., Owens G. K. Thrombin-induced mitogenesis of vascular SMC is partially mediated by autocrine production of PDGF-AA. Am. J. Physiol. 265:1993;C806.
36. Herbert J. M., Lamarche I., Dol F. Induction of vascular smooth muscle cell growth by selective activation of the thrombin receptor. FEBS Lett. 301:1992;155.
37. McNamara C. A., Sarenbock I. J., Gimple L. W., Fenton J. W., Coughlin S. R., Owens G. K. Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor. J. Clin. Invest. 91:1993;94.
38. Kanthou C., Benzakour O., Patel G., Deadman J., Kakkar V. V., Lupu F. Thrombin receptor activating peptide (TRAP) stimulates mitogenesis, c-fos and PDGF-A gene expression in human vascular smooth muscle cells. Thromb. Haemostasis. 74:1995;1340.
39. Jaye M., Schlessinger J., Dionne C. A. Fibroblast growth factor receptor tyrosine kinases: Molecular analysis and signal transduction. Biochem. Biophys. Acta. 1135:1992;185.
40. Weiss R. H., Maduri M. The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor. J. Biol. Chem. 268:1993;5724.
41. Rifkin D. B., Quarto N., Mignatti P., Bizik J., Moscatelli D. New observation on the intracellular localization and release of bFGF. Ann. N.Y. Acad. Sci. 638:1991;204.
42. Mignatti P., Morimoto T., Rifkin D. B. Basic Fibroblast Growth Factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex. J. Cell. Physiol. 151:1992;81.
43. Yu Z. X., Biro S., Fu Y. M., Sanchez J., Smale G., Sasse J., Ferrans V. J., Casscells W. Localization of basic fibroblastic growth factor in bovine endothelial cells: immunohistochemical and biochemical studies. Exp. Cell Res. 204:1993;247.