Yeast Pescadillo is required for multiple activities during 60s ribosomal subunit synthesis

RNA

Volumn 8, Issue 5, 2002, Pages 626-636

  Oeffinger, Marlene ^a   Lueng, Anthony ^a   Lamond, Angus ^a   Tollervey, David ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Nucleolus; Pre rRNA; Ribosome; RNA processing

Indexed keywords

PESCADILLO; PROTEIN DERIVATIVE; RIBOSOME PROTEIN; RIBOSOME RNA; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONTENT; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RIBOSOME SUBUNIT; RNA PROCESSING; RNA SYNTHESIS; YEAST;

BASE SEQUENCE; CELL NUCLEOLUS; HUMANS; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; PROTEINS; RECOMBINANT FUSION PROTEINS; RIBOSOMES; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0036247198     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838202020022     Document Type: Article

References (48)

1. Insertional mutagenesis in Zebrafish identifies two novel genes. Pescadillo and dead eye, essential for embryonic development
2. Functions of the exosome in rRNA, snoRNA and snRNA synthesis
3. Directed proteomic analysis of the human nucleolus
4. Identification of a 60S pre-ribosomal particle that is closely linked to nuclear export
5. Identification and functional analysis of two U3 binding sites on yeast pre-ribosomal RNA
6. Synthetic lethality with fibrillarin identifies NOP77p, a nucleolar protein required for pre-rRNA processing and modification
7. Nucleolar distribution of proteins B23 and nucleolin in mouse preimplantation embryos as visualized by immunoelectron microscopy
8. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
9. Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae
10. Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library
11. Ssf1p prevents premature processing of an early pre-60S ribosomal particle
12. Mdm2 association with p53 targets its ubiquitination
13. A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits
14. Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpi10p
15. The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5′ → 3′ exonucleases
16. The MDM2 RING-finger domain is required to promote p53 nuclear export
17. Purification of NSP1 reveals complex formation with 'GLFG' nucleoporins and a novel nuclear pore protein NIC96
18. The murine Pes1 gene encodes a nuclear protein containing a BRCT domain
19. Composition and functional characterization of yeast 66s ribosome assembly intermediates
20. The 5′ end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site
21. Nmd3p is a Crm1p-dependent adapter protein for nuclear export of the large ribosomal subunit
22. A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants
23. Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells
24. Protein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiae
25. One-step PCR mediated strategy for the construction of conditionally expressed and epitope tagged yeast proteins
26. The function and synthesis of ribosomes
27. Structural and functional analysis of the nucleolus of the fission yeast Schizosaccharomyces pombe
28. Functional compartmentalization of the nucleus in the budding yeast Saccharomyces cerevisiae
29. The nucleolus
30. Maturation and intranuclear transport of pre-ribosomes requires Noc proteins
31. A generic protein purification method for protein complex characterization and proteome exploration
32. Dual-specificity protein phosphatase Yvh1p, which is required for vegetative growth and sporulation, interacts with yeast Pescadillo homolog in Saccharomyces cerevisiae
33. Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonuclease
34. Structure and function of the nucleolus
35. A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability
36. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae
37. The nucleolus
38. Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit
39. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
40. Factors affecting nuclear export of the 60S ribosomal subunit in vivo
41. P19(ARF) stabilizes p53 by blocking nucleocytoplasmic shuttling of Mdm2
42. A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA
43. Temperature-sensitive mutations demonstrate roles for yeast fibrillarin in pre-rRNA processing, pre-rRNA methylation, and ribosome assembly
44. Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs
45. Ribosome synthesis in Saccharomyces cerevisiae
46. Nascent ribosomes
47. Nucleolar Arf sequesters Mdm2 and activates p53
48. Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53