Betulinic acid inhibits growth factor-induced in vitro angiogenesis via the modulation of mitochondrial function in endothelial cells

Japanese Journal of Cancer Research

Volumn 93, Issue 4, 2002, Pages 417-425

  Kwon, Ho Jeong ^a   Shim, Joong Sup ^a   Kim, Jin Hee ^a   Cho, Hyun Young ^b   Yum, Young Na ^b   Kim, Seung Hee ^b   Yu, Jaehoon ^c  

^a Sejong University   (South Korea)

^b Korea Food and Drug Administration   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

Aminopeptidase N; Angiogenesis; Betulinic acid; Mitochondrial permeability transition

Indexed keywords

ANGIOGENESIS INHIBITOR; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BETULIC ACID; BONGKREKIC ACID; CASPASE INHIBITOR; CYCLOSPORIN A; FAS ANTIGEN; FIBROBLAST GROWTH FACTOR; GLYCOPROTEIN; MEMBRANE PROTEIN; METALLOPROTEINASE; MICROSOMAL AMINOPEPTIDASE; MITOCHONDRIAL PERMEABILITY TRANSITION INHIBITOR; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RNA; SUCCINATE DEHYDROGENASE; TRITERPENOID; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL INVASION; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL;

ANIMALS; ANTIGENS, CD13; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AORTA; CATTLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLLAGEN; COLORING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; GROWTH SUBSTANCES; LAMININ; MITOCHONDRIA; NEOVASCULARIZATION, PATHOLOGIC; PERMEABILITY; PROTEOGLYCANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLIUM SALTS; THIAZOLES; TRITERPENES;

EID: 0036244345     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2002.tb01273.x     Document Type: Article

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