Organotypic rat cerebellar slice culture as a model to analyze the molecular pharmacology of GABAA receptors

European Neuropsychopharmacology

Volumn 12, Issue 3, 2002, Pages 201-208

  Davids, Eugen ^a,d   Hevers, Wulf ^a   Dämgen, Kerstin ^a   Zhang, Kehong ^b,c   Tarazi, Frank I ^b,c   Lüddens, Hartmut ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Cerebellum; GABAA receptor; Organotypic culture; Rat

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 8 AZIDO 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO[1,5 A][1,4]BENZODIAZEPINE 3 CARBOXYLIC ACID ETHYL ESTER; BENZODIAZEPINE; DIAZEPAM; FLUMAZENIL;

ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; BRAIN SLICE; CELL VIABILITY; CEREBELLUM CORTEX; CONTROLLED STUDY; DECAPITATION; DRUG EFFECT; GABAERGIC SYSTEM; MORPHOLOGY; NONHUMAN; POSTNATAL DEVELOPMENT; PRESERVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; TECHNIQUE;

AFFINITY LABELS; ANIMALS; ANIMALS, NEWBORN; AZIDES; BENZODIAZEPINES; BINDING SITES; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CULTURE TECHNIQUES; MALE; ORGAN SPECIFICITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

EID: 0036238126     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-977X(02)00024-X     Document Type: Article

References (47)

1. Postnatal development of the cerebellar cortex in the rat. I. The external germinal layer and the transitional molecular layer
2. Cerebellar localization and colocalization of GABA and calcium binding protein-D28K
3. A receptor mRNAs in cultured cerebellar granule neurons is dependent on developmental signals
4. Distribution, prevalence, and drug binding profile of gamma-aminobutyric acid type A receptor subtypes differing in the beta-subunit variant
5. Ro 15-4513: Partial inverse agonism at the BZR and interaction with ethanol
6. Calbindin D-28k and parvalbumin in the rat nervous system
7. Purkinje cell survival and axonal regeneration are age dependent: An in vitro study
8. A-receptor subtypes during postnatal development: An immunohistochemical study
9. Quantitative analysis of cell proliferation and differentiation in the cortex of the postnatal mouse cerebellum
10. Cytology of microcystic meningioma in crush preparation
11. Organotypic monolayer cultures of nervous tissue
12. Cell assembly patters of embryonic mouse cerebellar cells on carbohydrate-derivatized polylysine culture substrata
13. A channel subtypes
14. Human fetal brain cells in tissue culture: Their identification and motility
15. A receptors in rat cerebellum and thalamus
16. Electrical properties of oxytocin neurons in organotypic cultures from postnatal rat hypothalamus
17. Interactions of Ro15-4513, Ro15-1788 (flumazenil) and ethanol on measures of exploration and locomotion in rats
18. A receptor alpha subunit is expressed only in cerebellar granule cells
19. Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acid A receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2
20. 3H]Ro 15-4513 binding sites
21. A receptor function
22. Cytologic findings of medulloblastoma in crush smears
23. Neurotransmitters, neuropeptides and calcium binding proteins in developing human cerebellum: A review
24. A receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development
25. A receptor selective for a behavioural alcohol antagonist
26. A receptor structure and physiological properties in cultured cerebellar granule neurons
27. Luteinizing hormone-releasing hormone quantified in tissues and slice explant cultures of postnatal rat hypothalami
28. A receptor alpha 6 subunit gene
29. Gliogenesis in organotypic tissue culture of the spinal cord of the embryonic mouse. II. Autoradiographic studies
30. Excitatory and trophic action of GABA and related substances in newborn mice and organotypic cerebellar culture
31. A receptor alpha subunits expression with the properties of IPSCs in the developing thalamus
32. A receptor subtypes: Autoradiographic comparison of GABA, benzodiazepine, and convulsant binding sites in the rat central nervous system
33. Electrophysiological characteristics of substantia nigra neurons in organotypic cultures: Spontaneous and evoked activities
34. Sprouting of CA3 pyramidal neurons to the dentate gyrus in rat hippocampal organotypic cultures
35. Structure and subunit composition of GABA(A) receptors
36. A simple method for organotypic cultures of nervous tissue
37. Infection of organotypic slice cultures from rat central nervous tissue with Trypanosoma brucei brucei
38. Observation of the highly organized development of granule cells in rat cerebellar organotypic cultures
39. Differentiation of Purkinje cells in cerebellar slice cultures: An immunocytochemical and Golgi EM study
40. A receptor subtypes expressed in cerebellar granule cells: A developmental study
41. A receptor α1 and α6 subunits in cultured rat cerebellar granule cells
42. Organotypic brain slice cultures for functional analysis of alcohol-related disorders: Novel versus conventional preparations
43. A receptor α6 subunit
44. Binding of Ro 15-4513 to cerebellar membranes: Ontogeny and substrate specificity
45. A receptor diversity
46. Neurotoxicity evoked by N-methyl-D-aspartate in the organotypic static slice cultures of rat cerebral cortices: Effect of GABA(A) receptor activation
47. Changes in γ-aminobutyric acid type-A receptor subunit mRNAs, translation product expression, and receptor function during neuronal maturation in vitro