Analyses of differential gene expression in genetic hypertensive rats by microarray

Hypertension Research

Volumn 25, Issue 2, 2002, Pages 249-255

  Okuda, Tomohiko ^a   Sumiya, Toshiki ^a   Muzutani, Ken Ichi ^a   Tago, Naomi ^a   Miyata, Toshiyuki ^a   Tanabe, Tadashi ^a   Kato, Hiroshi ^a   Katsuya, Tomohiro ^a   Higaki, Jitsuo ^a   Ogihara, Toshio ^a   Tsujita, Yasuyuki ^a   Iwai, Naoharu ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Gene; Genetics; Hypertension

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; COMPLEMENTARY DNA; DYNAMIN; ELASTASE; ENALAPRIL; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN 70; HYDRALAZINE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; PRION PROTEIN; PROTHROMBIN; RETINOL BINDING PROTEIN; SUPEROXIDE DISMUTASE;

ARTERY CATHETERIZATION; ARTICLE; BLOOD PRESSURE MEASUREMENT; CHROMOSOME 2; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DNA MICROARRAY; FEMALE; FEMORAL ARTERY; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENETIC ANALYSIS; GENOTYPE; HEREDITARY HYPERTENSION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; QUANTITATIVE TRAIT LOCUS; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC TONE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CHROMOSOME MAPPING; GENE EXPRESSION; HYPERTENSION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, GENETIC; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED SHR; RATS, INBRED WKY;

EID: 0036237051     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.25.249     Document Type: Article

References (23)

1. Genetic dissection of complex traits
2. Molecular genetics of human blood pressure variation
3. Renal function curve: A key to understanding the pathogenesis of hypertension
4. The kidney and hypertension
5. Influence on blood pressure of renal isografts between spontaneously hypertensive and normotensive rats, utilizing the F1 hybrid
6. Hypertension transmitted by kidneys from stroke-prone spontaneously hypertensive rats
7. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
8. Hypotensive effect associated with a phospholipase C-d1 gene mutation in the spontaneously hypertensive rat
9. A neuropeptide Y chromosome 4 cosegregates with blood pressure in the spontaneously hypertensive rat
10. Interval mapping of multiple quantitative trait loci
11. cDNA cloning and functional characterization of rat intestinal monocarboxylate transporter
12. Cloning and sequence analysis of a cDNA for a rat liver glutathione S-transferase Yb subunit
13. Sa gene and blood pressure cosegregation using Dahl salt-sensitive rats
14. A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure
15. Genetic mapping of two blood pressure quantitative trait loci on rat chromosome 1
16. Isolation of a chromosome 1 region that contributes to high blood pressure and salt sensitivity
17. Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats
18. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat
19. Quantitative trait loci in genetically hypertensive rats: Possible sex specificity
20. Genetic isolation of a chromosome 1 region affecting blood pressure in the spontaneously hypertensive rat
21. Applicability of a "speed" congenic strategy to dissect blood pressure quantitative trait loci on rat chromosome 2
22. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
23. Activation of heat shock protein (hsp)70 and proto-oncogene expression by alpha1 adrenergic agonist in rat aorta with age