The peroxisome proliferator-activated receptor α-selective activator ciprofibrate upregulates expression of genes encoding fatty acid oxidation and ketogenesis enzymes in rat brain

Neuropharmacology

Volumn 42, Issue 5, 2002, Pages 724-730

  Cullingford, Tim E ^a,c   Dolphin, Colin T ^b   Sato, Hitoshi ^b  

^a SHOWA UNIVERSITY   (Japan)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c Ashcroft   (United Kingdom)

Author keywords

Ciprofibrate; Mitochondrial 3 hydroxy 3 methylglutaryl CoA synthase; Peroxisome proliferator activated receptor alpha; Valproate

Indexed keywords

CIPROFIBRATE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; KETONE BODY; LIPID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; FATTY ACID OXIDATION; GENE EXPRESSION REGULATION; GENETIC CODE; IN VIVO STUDY; INFLAMMATION; KETOGENESIS; LIVER LEVEL; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; RIBONUCLEASE PROTECTION ASSAY;

ACYL-COA DEHYDROGENASE; ACYL-COA OXIDASE; ANIMALS; BRAIN; CLOFIBRIC ACID; COENZYME A LIGASES; FATTY ACID DESATURASES; FATTY ACIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; KETONES; LIVER; MALE; OXIDATION-REDUCTION; OXIDOREDUCTASES; PEROXISOME PROLIFERATORS; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 0036236378     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00014-X     Document Type: Article

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