Incorporation of selected nucleoside phosphonates and anti-human immunodeficiency virus nucleotide analogues into DNA by human DNA polymerases α, β and γ

Antiviral Chemistry and Chemotherapy

Volumn 8, Issue 3, 1997, Pages 187-195

  Cihlar, T ^a   Chen, M S ^a  

^a GILEAD SCIENCES   (United States)

Author keywords

anti HIV; Antiviral; DNA polymerases; DNA synthesis; nucleoside phosphonates

Indexed keywords

2' DEOXY 3' THIACYTIDINE TRIPHOSPHATE; 2',3' DIDEHYDRO 3' DEOXYTHYMIDINE TRIPHOSPHATE; 2',3' DIDEOXYADENOSINE TRIPHOSPHATE; 2',3' DIDEOXYCYTIDINE 5' TRIPHOSPHATE; 9 (2 PHOSPHONOMETHOXYETHYL)ADENINE DIPHOSPHATE; 9 (2 PHOSPHONOMETHOXYETHYL)GUANINE DIPHOSPHATE; 9 (2 PHOSPHONOMETHOXYPROPYL)ADENINE DIPHOSPHATE; 9 (2 PHOSPHONONOMETHOXYPROPYL) 2,6 DIAMINOPURINE DIPHOSPHATE; 9 [2,5 DIHYDRO 5 (PHOSPHONOMETHOXY) 2 FURANYL]ADENINE DIPHOSPHATE; ADEFOVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DNA; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE GAMMA; DNA POLYMERASE; NUCLEOSIDE DERIVATIVE; NUCLEOTIDE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; THYMIDINE TRIPHOSPHATE; UNCLASSIFIED DRUG; ZIDOVUDINE 5' TRIPHOSPHATE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; PRIORITY JOURNAL;

EID: 0030969223     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632029700800302     Document Type: Article

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